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Tag Content
UUCD2 ID IUUC-Cfa-021004
UUCD1 version UUC-CaF-00978
Ensembl Protein ID ENSCAFP00000017120.3
UniProt Accession F1PF24; F1PF24_CANLF
Genbank Protein ID ENSCAFP00000017120
Protein Name Uncharacterized protein
Genbank Nucleotide ID AAEX03012231
Gene Name USP19
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSCAFG00000011567.5 ENSCAFT00000043874.2 ENSCAFP00000036675.1
ENSCAFG00000011567.5 ENSCAFT00000018484.4 ENSCAFP00000017120.3
ENSCAFG00000011567.5 ENSCAFT00000018474.4 ENSCAFP00000017110.4
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 6.40e-115 384.2 663 1380
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           tGl NlgNtC+mNSv+Q+Lsn++elr+++++ +++ ++n +np ++ g+l+  ++ l+++lwk++++a++p++l+++++++a++f+g
   Q: 663  TGLVNLGNTCFMNSVIQSLSNTRELRDFFHDrSFETEINYNNPLGTGGRLAIGFAVLLRALWKGTHHAFQPSKLKAIVASKASQFTG 749
           7*****************************9999***************************************************** PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssreep 168
           y+q+DaqEf+aflld+l+e+l++ +nkp++e+ ++d   ++de     a++++k++n+s+i+dlFqgq+ks+++c+ c++vs +++p
   Q: 750  YAQHDAQEFMAFLLDGLHEDLNRIQNKPYTETVDSD--GRPDEvvaeeAWQRHKMRNDSFIVDLFQGQYKSKLVCPVCAKVSITFDP 834
           ********************************9999..6666666777*************************************** PP
   S: 169  fldlslpvpgkeetkke...................................................................... 185
           fl+l++p+p+k++  +                                                                       
   Q: 835  FLYLPVPLPQKQKVLPVfyfarephskpikflvsiskenssasevldslsqsvhvkpenlrlaeviknrfhrvflpshsldtvspsd 921
           ************87666********************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 922  tllcfellspelakervvvlevqqrpqvpsipiskcaacqrkqqsedeklkrctrcyrvgycnqlcqkthwpdhkglcrpenigypf 1008
           *************************************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 1009 lvsvpasrliyarlaqllegyarysvsvfqppfqpgrmalesqgpgcttllstssleagdserdpiqppelqlvtpvaegdtgvpra 1095
           *************************************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 1096 waapdrgpvpstsgvssevlasgpvevgslpagervsrpeaavpgyqhpseamnshtpqffiykidasnreqrledkgdtplelged 1182
           *************************************************************************************** PP
   S: 186  ..........................................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevL 230
                                                     +l++cL+ ft++e l  e+++yc++ck+++ea+k+l l++lP+vL
   Q: 1183 cslalvwrnnerlqefvlvaskelecaedpgsageaaraghfTLDQCLNLFTRPEVLAPEEAWYCPQCKQHREASKQLLLWRLPNVL 1269
           *************************************************************************************** PP
   S: 231  ilhLkRfsfseeqksrekinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk........Wll 308
           i++LkRfsf++  +++ kin+ vefp + Ldls+fc+ ++e+q    +Y+L+av++H+G++ +GHY+a+++  +++        W l
   Q: 1270 IVQLKRFSFRSFIWRD-KINDLVEFPVRnLDLSKFCIGQKEEQ--LPSYDLYAVINHYGGMIGGHYTACARLPNDRssqrsdvgWRL 1353
           ************8886.**********9**********99888..9**************************544445566777*** PP
   S: 309  fdDskVtevkeeevleetgstaYvlfYkrr 338
           fdDs+Vt+v+e++v++   + aYvlfY+rr
   Q: 1354 FDDSTVTTVDESQVVT---RYAYVLFYRRR 1380
           ****************...********996 PP
   
Organism Canis familiaris
Protein Sequence
(Fasta)
PEPRAGCQGP KRAGGGGLAR LSVPCWRIWP QRVAKIAGPG RKRRSPDPDA VTDPGALWLS 60
TKRLKMSGGA SATGPRRGPP GLEEATSKKK QKDRANQESK DGDPRRDTER RTQSRLGRVS 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Cfa-021004|DUB,USP|Canis familiaris
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CTGCTGCAGG GCCCACTAGG CGACCAGTAC CAGACAGTGA AGGCCTTGGC TGAGCGCAAG 60
GCCCAGGGTG TGCTGGCTGC ACAGGTGCGG GCAGAACAAC TTCGGGATGA AGCTCGTGGC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Cfa-021004|DUB,USP|Canis familiaris
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
Interpro

IPR007052--CS_dom
IPR008978--HSP20-like_chaperone
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR002893--Znf_MYND
PROSITE

PS51203--CS
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS01360--ZF_MYND_1
PS50865--ZF_MYND_2
Pfam

PF04969--CS
PF00443--UCH
PF01753--zf-MYND
Gene Ontology

GO:0005829--C:cytosol
GO:0005789--C:endoplasmic reticulum membrane
GO:1990380--F:Lys48-specific deubiquitinase activity
GO:0046872--F:metal ion binding
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:1901799--P:negative regulation of proteasomal protein catabolic process
GO:0048642--P:negative regulation of skeletal muscle tissue development
GO:0050821--P:protein stabilization
GO:1900037--P:regulation of cellular response to hypoxia
GO:1904292--P:regulation of ERAD pathway
GO:0030433--P:ubiquitin-dependent ERAD pathway
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001999 Ailuropoda melanoleuca 95.44 0.00e+00 2625.00
IUUC-Apl-003368 Anas platyrhynchos 67.84 0.00e+00 1774.00
IUUC-Aca-004267 Anolis carolinensis 68.43 0.00e+00 1671.00
IUUC-Ame-010970 Astyanax mexicanus 70.57 0.00e+00 1350.00
IUUC-Bta-012905 Bos taurus 92.06 0.00e+00 2521.00
IUUC-Cja-018789 Callithrix jacchus 89.68 0.00e+00 2346.00
IUUC-Cpo-021529 Cavia porcellus 87.37 0.00e+00 2258.00
IUUC-Csa-024035 Chlorocebus sabaeus 92.56 0.00e+00 2357.00
IUUC-Cho-025036 Choloepus hoffmanni 81.94 0.00e+00 1220.00
IUUC-Cin-025451 Ciona intestinalis 43.41 1.00e-85 311.00
IUUC-Csv-025931 Ciona savignyi 36.30 4.00e-110 392.00
IUUC-Dre-028556 Danio rerio 69.99 0.00e+00 1323.00
IUUC-Dno-029240 Dasypus novemcinctus 92.16 0.00e+00 2112.00
IUUC-Dor-030495 Dipodomys ordii 95.27 0.00e+00 1198.00
IUUC-Ete-032741 Echinops telfairi 92.41 0.00e+00 1870.00
IUUC-Eca-033661 Equus caballus 92.44 0.00e+00 2384.00
IUUC-Eeu-034648 Erinaceus europaeus 92.13 0.00e+00 831.00
IUUC-Fca-035646 Felis catus 95.93 0.00e+00 2603.00
IUUC-Fal-037094 Ficedula albicollis 70.23 0.00e+00 1707.00
IUUC-Gmo-038869 Gadus morhua 72.37 0.00e+00 843.00
IUUC-Gga-041170 Gallus gallus 67.79 0.00e+00 1659.00
IUUC-Gac-041901 Gasterosteus aculeatus 69.03 0.00e+00 1323.00
IUUC-Ggo-044708 Gorilla gorilla 90.58 0.00e+00 2362.00
IUUC-Hsa-046791 Homo sapiens 94.83 0.00e+00 2007.00
IUUC-Itr-048892 Ictidomys tridecemlineatus 89.02 0.00e+00 2269.00
IUUC-Lch-050456 Latimeria chalumnae 55.83 0.00e+00 1169.00
IUUC-Loc-052861 Lepisosteus oculatus 59.98 0.00e+00 1152.00
IUUC-Laf-053788 Loxodonta africana 90.27 0.00e+00 2258.00
IUUC-Mcc-055693 Macaca mulatta 89.81 0.00e+00 2435.00
IUUC-Meu-055921 Macropus eugenii 78.85 0.00e+00 1472.00
IUUC-Mga-059879 Meleagris gallopavo 66.28 0.00e+00 1707.00
IUUC-Mmr-060802 Microcebus murinus 91.77 0.00e+00 2405.00
IUUC-Mdo-061856 Monodelphis domestica 77.50 0.00e+00 1566.00
IUUC-Mmu-063874 Mus musculus 92.35 0.00e+00 2219.00
IUUC-Mpu-066166 Mustela putorius furo 96.01 0.00e+00 2617.00
IUUC-Nle-070161 Nomascus leucogenys 90.13 0.00e+00 2411.00
IUUC-Opr-071015 Ochotona princeps 94.15 0.00e+00 1959.00
IUUC-Ont-072308 Oreochromis niloticus 67.10 0.00e+00 1386.00
IUUC-Oan-072723 Ornithorhynchus anatinus 68.44 0.00e+00 1584.00
IUUC-Ocu-073938 Oryctolagus cuniculus 90.01 0.00e+00 2480.00
IUUC-Ola-086375 Oryzias latipes 68.07 0.00e+00 1357.00
IUUC-Oga-088297 Otolemur garnettii 90.91 0.00e+00 2335.00
IUUC-Oar-089675 Ovis aries 89.69 0.00e+00 1741.00
IUUC-Ptr-091621 Pan troglodytes 94.44 0.00e+00 2000.00
IUUC-Pan-092118 Papio anubis 90.12 0.00e+00 2574.00
IUUC-Pfo-097246 Poecilia formosa 67.16 0.00e+00 1343.00
IUUC-Pab-098551 Pongo abelii 93.87 0.00e+00 1981.00
IUUC-Pca-100158 Procavia capensis 86.10 0.00e+00 2227.00
IUUC-Pva-103160 Pteropus vampyrus 91.62 0.00e+00 2326.00
IUUC-Rno-105355 Rattus norvegicus 92.34 0.00e+00 2248.00
IUUC-Sha-107057 Sarcophilus harrisii 72.99 0.00e+00 1946.00
IUUC-Sar-113011 Sorex araneus 91.34 0.00e+00 1526.00
IUUC-Ssc-115761 Sus scrofa 93.02 0.00e+00 2565.00
IUUC-Tgu-116956 Taeniopygia guttata 63.97 0.00e+00 790.00
IUUC-Tru-118739 Takifugu rubripes 67.53 0.00e+00 1367.00
IUUC-Tsy-118827 Tarsius syrichta 82.59 0.00e+00 1250.00
IUUC-Tni-119921 Tetraodon nigroviridis 61.45 0.00e+00 1403.00
IUUC-Tbe-128017 Tupaia belangeri 91.57 0.00e+00 1923.00
IUUC-Ttr-128869 Tursiops truncatus 95.53 0.00e+00 2276.00
IUUC-Vpa-130427 Vicugna pacos 97.44 0.00e+00 941.00
IUUC-Xtr-132734 Xenopus tropicalis 61.60 0.00e+00 1614.00
Created Date 25-Jun-2017

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