iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-052710

Ensembl Protein ID

ENSLOCP00000000324.1

UniProt Accession

W5LW17; W5LW17_LEPOC

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000000294.1	ENSLOCT00000000324.1	ENSLOCP00000000324.1
ENSLOCG00000000294.1	ENSLOCT00000000369.1	ENSLOCP00000000368.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.10e-33	113.9	311	348
UBD/Beta-Prp	8.90e-47	159.8	266	547

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDlrtgvllk 37
           gH++ +tc+ f  s+++lv+G++Dg +k+W++  g++lk
   Q: 311  GHSA-ITCMTFdiSGRRLVTGGRDGCLKIWNFNNGHCLK 348
           6777.******998899*****************99986 PP

UBD/Beta-Prp

   S: 8    hhksvitcvkfspdksllatgsrdgtikvwdvttgkl...lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlk.. 91
           +hk+++ c  +s++ +++++  + + +kvwd++tg     +    gh+ ++t+++f+ +g  lvtg++D+ +k+w++++g c+ +lk  
   Q: 266  SHKEPVLCCGYSKEFRQVVSCTEGSVVKVWDFDTGGQvfeFGDAHGHS-AITCMTFDISGRRLVTGGRDGCLKIWNFNNGHCLKILKke 353
           688888889999999999999999999********9944445556666.8*************************************99 PP
   S: 92   ghedsvlslsfsp.sg.dklvsGshdrtirvwdletgqclee..........tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlkt 168
           g++d+v+++++ + ++ +++ + ++dr i ++  +++ + +           + sgh++ + c++  p  +ll+++++D+ + +W++ +
   Q: 354  GKSDEVCDCTYVKvNRsNYVMAVGWDRRIDMYFDSNDDVHHIqnpqpywqddLRSGHKEDILCIAQCP-PSLLATSGYDGEIVVWNMVS 441
           *************96659999999*******9888888777789999999**********99997766.69****************** PP
   S: 169  gkllrtl...........tgghtdsvyslsfdsng.......kelvsgsldgtvklwdlq.tgecvrtlnght..dnvksvrfspnder 236
           g +  +l           + g ++sv s++f +++        +lvs +  g+v++w+l   g+   t+++ +    ++ +++  ++++
   Q: 442  GHIHSRLvtpvppectdaKVGIDKSVSSVTFLKTRirnnesaACLVSSGPQGYVNFWSLVhGGNLFATFEASRmkCLITKMAVNAEETL 530
           ***************999666999999999888888889999*****************955677889999774467888999999999 PP
   S: 237  lvsgssDgsiriWdlrs 253
           l+++   g i+++d++ 
   Q: 531  LYVADLSGYIYVYDTKD 547
           99999999999999765 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

ISILQGCVNI IVMTSVGETL RLWKKLPKVE NVPNIGIDNA VLSPHITYIR WKVHEDWVTQ 60
LKYYEGIRAV ISTSNHESSA LVIDSVFSCL HKGCTFPTTN IEQQMREIEE GKGKRSQAYS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATTTCAATCT TACAGGGCTG CGTGAACATA ATTGTAATGA CATCAGTTGG AGAGACATTA 60
AGGTAATTAT GTTACTTAAA AAAATTAATA AAATGAATTA CAAAAGGAAT GTTTTATCGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001921	Ailuropoda melanoleuca	57.84	2.00e-177	615.00
IUUC-Apl-003630	Anas platyrhynchos	30.66	4.00e-24	106.00
IUUC-Ame-011582	Astyanax mexicanus	60.03	0.00e+00	809.00
IUUC-Bta-013034	Bos taurus	56.52	2.00e-166	579.00
IUUC-Cin-025633	Ciona intestinalis	43.65	1.00e-99	355.00
IUUC-Csv-026326	Ciona savignyi	42.86	3.00e-131	461.00
IUUC-Dre-027573	Danio rerio	56.96	0.00e+00	788.00
IUUC-Dno-030073	Dasypus novemcinctus	54.72	0.00e+00	702.00
IUUC-Eca-033354	Equus caballus	53.32	5.00e-163	567.00
IUUC-Fca-036185	Felis catus	54.44	3.00e-158	551.00
IUUC-Gmo-039551	Gadus morhua	62.10	1.00e-114	406.00
IUUC-Gga-041212	Gallus gallus	28.61	1.00e-38	155.00
IUUC-Gac-041482	Gasterosteus aculeatus	59.36	1.00e-180	625.00
IUUC-Itr-049019	Ictidomys tridecemlineatus	57.34	8.00e-179	620.00
IUUC-Lch-050242	Latimeria chalumnae	67.59	0.00e+00	916.00
IUUC-Mdo-062347	Monodelphis domestica	58.27	0.00e+00	803.00
IUUC-Mmu-063878	Mus musculus	55.50	0.00e+00	765.00
IUUC-Mpu-065721	Mustela putorius furo	52.66	1.00e-61	229.00
IUUC-Ont-071688	Oreochromis niloticus	58.05	7.00e-174	603.00
IUUC-Oan-072752	Ornithorhynchus anatinus	56.01	1.00e-153	536.00
IUUC-Ocu-074780	Oryctolagus cuniculus	46.79	1.00e-68	253.00
IUUC-Ola-086449	Oryzias latipes	56.10	3.00e-154	538.00
IUUC-Pma-094599	Petromyzon marinus	54.41	4.00e-171	594.00
IUUC-Ppa-095538	Physcomitrella patens	35.98	7.00e-20	92.40
IUUC-Pfo-096408	Poecilia formosa	55.12	0.00e+00	751.00
IUUC-Rno-105331	Rattus norvegicus	52.62	4.00e-153	535.00
IUUC-Sha-106832	Sarcophilus harrisii	61.29	0.00e+00	639.00
IUUC-Smo-109247	Selaginella moellendorffii	31.12	1.00e-57	218.00
IUUC-Ssc-116310	Sus scrofa	56.54	8.00e-167	580.00
IUUC-Tru-117666	Takifugu rubripes	54.18	2.00e-163	568.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence