iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Details
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Spo-108311

UUCD1 version

UUC-ScP-00258

Ensembl Protein ID

SPAC30D11.13.1:pep

UniProt Accession

P40984; UBC9_SCHPO

Genbank Protein ID

CAA57438.1; CAA91899.1

Protein Name

SUMO-conjugating enzyme ubc9; SUMO protein ligase; Ubiquitin carrier protein 9; Ubiquitin carrier protein hus5; Ubiquitin-conjugating enzyme E2-18 kDa; Ubiquitin-protein ligase hus5

Genbank Nucleotide ID

X81846; CU329670

Gene Name

hus5; ubc9; SPAC30D11.13

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
SPAC30D11.13	SPAC30D11.13.1	SPAC30D11.13.1:pep

Annotation

mRNA Expression
GEO
Protein-protein Interaction
iRefIndex	Mentha
Protein 3D Structure
PDB	MMDB
Protein Expression/Proteomics

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E2/UBC	E2_UBC	15359282

Classification

Family	E-value	Score	Start	End
E2/UBC	1.90e-50	168.3	8	149

Active Site

Position(s)	Description	Evidence
93	Glycyl thioester intermediate	{ECO:0000255\|PROSITE-ProRule:PRU00388, ECO:0000255\|PROSITE-ProRule:PRU10133}

Domain Profile

E2/UBC

   S: 1    Rlkkelkelekdppegisakpvdesd....ltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilk 87
           Rl++e k++++d+p g+ akp ++sd    l++w+v i G+++t +egg++kl++ fpe+YP++PPk++f+ ++fhPnvy++G+vClsil+
   Q: 8    RLQEERKQWRRDHPFGFYAKPCKSSDggldLMNWKVGIPGKPKTSWEGGLYKLTMAFPEEYPTRPPKCRFTPPLFHPNVYPSGTVCLSILN 98
           99**********************999999************************************************************* PP
   S: 88   eeekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           eee W+pa++++++ll+iq ll++pn++sp+++ea++++kk++ ey+k+vr
   Q: 99   EEEGWKPAITIKQILLGIQDLLDDPNIASPAQTEAYTMFKKDKVEYEKRVR 149
           *************************************************98 PP

Organism

Schizosaccharomyces pombe

Functional Description
(View)

Catalyzes the covalent attachment of ubiquitin-like protein SUMO/Smt3 to other proteins. Required for efficient recovery from DNA damage or S-phase arrest and normal mitosis. This may be as part of a checkpoint independent recovery process.

Protein Sequence
(Fasta)

MSSLCKTRLQ EERKQWRRDH PFGFYAKPCK SSDGGLDLMN WKVGIPGKPK TSWEGGLYKL 60
TMAFPEEYPT RPPKCRFTPP LFHPNVYPSG TVCLSILNEE EGWKPAITIK QILLGIQDLL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCTTGTATCC CATTCTGTCT CGCTTGCCCC TACTTTTTAT CTTTTATATA CCATAATGAA 60
CGCTGCCGCT ACTAACCATA CCCCGATTTT ACATTTCGGA CTCCCAAGGA CGTACAAAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0002--3D-structure
KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0227--DNA damage
KW-0436--Ligase
KW-0547--Nucleotide-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR027230--Ubc9
IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0005720--C:nuclear heterochromatin
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0016874--F:ligase activity
GO:0061656--F:SUMO conjugating enzyme activity
GO:0019789--F:SUMO transferase activity
GO:0006974--P:cellular response to DNA damage stimulus
GO:0016925--P:protein sumoylation

KEGG

spo:SPAC30D11.13

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000510	Aegilops tauschii	65.71	4.00e-41	158.00
IUUC-Aml-002383	Ailuropoda melanoleuca	66.24	1.00e-62	229.00
IUUC-Atr-002982	Amborella trichopoda	58.97	8.00e-46	174.00
IUUC-Apl-003840	Anas platyrhynchos	66.24	1.00e-62	229.00
IUUC-Aca-004772	Anolis carolinensis	66.24	1.00e-62	229.00
IUUC-Aly-005652	Arabidopsis lyrata	61.44	5.00e-56	207.00
IUUC-Ath-007084	Arabidopsis thaliana	61.44	5.00e-56	207.00
IUUC-Ago-007998	Ashbya gossypii	58.33	7.00e-55	204.00
IUUC-Acl-008040	Aspergillus clavatus	74.51	1.00e-58	216.00
IUUC-Afl-008563	Aspergillus flavus	73.86	1.00e-58	216.00
IUUC-Afu-008873	Aspergillus fumigatus	75.35	1.00e-54	203.00
IUUC-Ani-009222	Aspergillus nidulans	71.90	3.00e-57	211.00
IUUC-Ang-009740	Aspergillus niger	65.36	2.00e-56	209.00
IUUC-Aor-010170	Aspergillus oryzae	74.51	6.00e-59	217.00
IUUC-Ate-010410	Aspergillus terreus	73.86	5.00e-59	217.00
IUUC-Ame-011711	Astyanax mexicanus	65.61	2.00e-62	228.00
IUUC-Bgr-012012	Blumeria graminis	66.67	4.00e-60	221.00
IUUC-Bta-013269	Bos taurus	66.24	1.00e-62	229.00
IUUC-Bci-013748	Botrytis cinerea	67.53	4.00e-53	197.00
IUUC-Bdi-014883	Brachypodium distachyon	60.78	9.00e-56	206.00
IUUC-Bol-015738	Brassica oleracea	61.54	3.00e-48	181.00
IUUC-Bra-017925	Brassica rapa	61.54	2.00e-48	182.00
IUUC-Cel-018448	Caenorhabditis elegans	60.26	1.00e-58	216.00
IUUC-Cja-019349	Callithrix jacchus	66.24	1.00e-62	229.00
IUUC-Cfa-021008	Canis familiaris	65.18	1.00e-43	166.00
IUUC-Cpo-021324	Cavia porcellus	66.24	1.00e-62	229.00
IUUC-Cre-022836	Chlamydomonas reinhardtii	62.42	8.00e-59	217.00
IUUC-Csa-024207	Chlorocebus sabaeus	66.24	1.00e-62	229.00
IUUC-Cin-025734	Ciona intestinalis	66.23	3.00e-62	228.00
IUUC-Csv-026049	Ciona savignyi	63.64	2.00e-61	225.00
IUUC-Cgl-026699	Colletotrichum gloeosporioides	76.06	5.00e-65	237.00
IUUC-Cne-027034	Cryptococcus neoformans	66.24	9.00e-66	240.00
IUUC-Cme-027203	Cyanidioschyzon merolae	57.32	2.00e-48	182.00
IUUC-Dre-027701	Danio rerio	65.61	4.00e-62	228.00
IUUC-Dno-030037	Dasypus novemcinctus	66.24	1.00e-62	229.00
IUUC-Dor-031037	Dipodomys ordii	65.69	5.00e-54	201.00
IUUC-Dse-031366	Dothistroma septosporum	70.59	2.00e-64	235.00
IUUC-Dme-031818	Drosophila melanogaster	69.23	5.00e-64	234.00
IUUC-Ete-032517	Echinops telfairi	66.42	1.00e-54	202.00
IUUC-Eca-033789	Equus caballus	66.24	1.00e-62	229.00
IUUC-Fca-035851	Felis catus	66.24	1.00e-62	229.00
IUUC-Fal-037177	Ficedula albicollis	66.24	1.00e-62	229.00
IUUC-Fox-037789	Fusarium oxysporum	75.82	1.00e-70	256.00
IUUC-Fso-038166	Fusarium solani	75.82	3.00e-70	254.00
IUUC-Gmo-039482	Gadus morhua	65.61	3.00e-62	228.00
IUUC-Ggr-039892	Gaeumannomyces graminis	79.26	3.00e-64	236.00
IUUC-Gga-041199	Gallus gallus	66.24	1.00e-62	229.00
IUUC-Gac-042250	Gasterosteus aculeatus	65.61	3.00e-62	228.00
IUUC-Gma-043827	Glycine max	61.15	7.00e-57	210.00
IUUC-Ggo-045530	Gorilla gorilla	66.24	1.00e-62	229.00
IUUC-Hsa-046248	Homo sapiens	66.24	1.00e-62	229.00
IUUC-Hvu-047363	Hordeum vulgare	59.48	7.00e-55	204.00
IUUC-Itr-048429	Ictidomys tridecemlineatus	66.24	1.00e-62	229.00
IUUC-Kpa-049362	Komagataella pastoris	65.79	6.00e-60	220.00
IUUC-Lch-050202	Latimeria chalumnae	66.24	2.00e-62	229.00
IUUC-Lpe-051643	Leersia perrieri	60.13	8.00e-55	204.00
IUUC-Loc-052357	Lepisosteus oculatus	65.61	3.00e-62	228.00
IUUC-Lma-053142	Leptosphaeria maculans	71.90	1.00e-67	246.00
IUUC-Laf-053577	Loxodonta africana	66.24	1.00e-62	229.00
IUUC-Mcc-054925	Macaca mulatta	66.24	1.00e-62	229.00
IUUC-Meu-056094	Macropus eugenii	54.74	6.00e-41	157.00
IUUC-Mor-057141	Magnaporthe oryzae	73.86	4.00e-69	251.00
IUUC-Mpo-057613	Magnaporthe poae	77.78	2.00e-62	229.00
IUUC-Mtr-058465	Medicago truncatula	62.99	2.00e-58	216.00
IUUC-Mla-059115	Melampsora laricipopulina	67.97	3.00e-65	238.00
IUUC-Mga-059384	Meleagris gallopavo	66.24	1.00e-62	229.00
IUUC-Mvi-060328	Microbotryum violaceum	69.23	4.00e-57	211.00
IUUC-Mmr-061541	Microcebus murinus	66.24	1.00e-62	229.00
IUUC-Mdo-062540	Monodelphis domestica	66.24	1.00e-62	229.00
IUUC-Mmu-063818	Mus musculus	66.24	1.00e-62	229.00
IUUC-Mac-064641	Musa acuminata	61.44	7.00e-56	207.00
IUUC-Mpu-065734	Mustela putorius furo	66.24	1.00e-62	229.00
IUUC-Mlu-067619	Myotis lucifugus	66.24	1.00e-62	229.00
IUUC-Nfi-068567	Neosartorya fischeri	75.16	4.00e-59	218.00
IUUC-Ncr-068897	Neurospora crassa	74.68	3.00e-69	251.00
IUUC-Nle-069541	Nomascus leucogenys	66.03	7.00e-62	227.00
IUUC-Ont-071585	Oreochromis niloticus	65.61	3.00e-62	228.00
IUUC-Oan-073178	Ornithorhynchus anatinus	57.89	8.00e-25	102.00
IUUC-Ocu-074588	Oryctolagus cuniculus	62.42	1.00e-56	209.00
IUUC-Oba-075803	Oryza barthii	61.44	7.00e-56	207.00
IUUC-Obr-076591	Oryza brachyantha	60.78	3.00e-56	208.00
IUUC-Ogl-077864	Oryza glaberrima	61.44	7.00e-56	207.00
IUUC-Ogu-077979	Oryza glumaepatula	61.44	6.00e-56	207.00
IUUC-Oin-080163	Oryza indica	61.44	7.00e-56	207.00
IUUC-Olo-080940	Oryza longistaminata	54.97	8.00e-47	177.00
IUUC-Ome-081909	Oryza meridionalis	61.44	6.00e-56	207.00
IUUC-Oni-082410	Oryza nivara	61.44	7.00e-56	207.00
IUUC-Opu-083206	Oryza punctata	59.62	2.00e-55	205.00
IUUC-Oru-084706	Oryza rufipogon	61.44	7.00e-56	207.00
IUUC-Osa-086079	Oryza sativa	61.44	7.00e-56	207.00
IUUC-Ola-086314	Oryzias latipes	64.97	4.00e-62	228.00
IUUC-Olu-087900	Ostreococcus lucimarinus	54.78	2.00e-52	196.00
IUUC-Oga-088729	Otolemur garnettii	66.42	8.00e-55	203.00
IUUC-Oar-090221	Ovis aries	66.24	3.00e-62	229.00
IUUC-Ptr-090528	Pan troglodytes	66.24	1.00e-62	229.00
IUUC-Pan-092834	Papio anubis	66.24	1.00e-62	229.00
IUUC-Psi-093001	Pelodiscus sinensis	66.24	1.00e-62	229.00
IUUC-Pma-094539	Petromyzon marinus	66.88	6.00e-63	230.00
IUUC-Pno-094954	Phaeosphaeria nodorum	69.48	1.00e-65	239.00
IUUC-Ppa-095314	Physcomitrella patens	59.62	4.00e-56	207.00
IUUC-Pfo-097457	Poecilia formosa	65.61	3.00e-62	228.00
IUUC-Pab-098205	Pongo abelii	66.24	1.00e-62	229.00
IUUC-Pop-099575	Populus trichocarpa	62.18	9.00e-49	183.00
IUUC-Pca-100603	Procavia capensis	66.42	3.00e-54	202.00
IUUC-Ppe-101501	Prunus persica	62.18	3.00e-48	181.00
IUUC-Pva-103251	Pteropus vampyrus	54.74	8.00e-40	153.00
IUUC-Pte-104067	Pyrenophora teres	69.28	5.00e-65	237.00
IUUC-Pyt-104436	Pyrenophora triticirepentis	68.63	4.00e-65	238.00
IUUC-Rno-105794	Rattus norvegicus	66.24	1.00e-62	229.00
IUUC-Sce-106308	Saccharomyces cerevisiae	61.69	6.00e-59	217.00
IUUC-Sha-106997	Sarcophilus harrisii	59.75	2.00e-54	202.00
IUUC-Sja-108000	Schizosaccharomyces japonicus	92.95	9.00e-78	280.00
IUUC-Smo-108685	Selaginella moellendorffii	59.21	8.00e-46	173.00
IUUC-Sit-110037	Setaria italica	60.13	5.00e-55	204.00
IUUC-Sly-111886	Solanum lycopersicum	62.18	1.00e-47	179.00
IUUC-Stu-111975	Solanum tuberosum	61.44	1.00e-50	190.00
IUUC-Sbi-114672	Sorghum bicolor	60.13	1.00e-54	203.00
IUUC-Sre-114957	Sporisorium reilianum	75.64	2.00e-72	262.00
IUUC-Ssc-116173	Sus scrofa	66.24	1.00e-62	229.00
IUUC-Tgu-116668	Taeniopygia guttata	66.24	1.00e-62	229.00
IUUC-Tru-118365	Takifugu rubripes	65.61	1.00e-62	229.00
IUUC-Tni-120455	Tetraodon nigroviridis	65.61	6.00e-63	230.00
IUUC-Tca-120956	Theobroma cacao	60.26	2.00e-55	206.00
IUUC-Tre-121927	Trichoderma reesei	76.47	1.00e-71	259.00
IUUC-Tvi-122363	Trichoderma virens	75.82	5.00e-71	257.00
IUUC-Tae-125311	Triticum aestivum	61.54	8.00e-56	207.00
IUUC-Tur-126625	Triticum urartu	60.90	2.00e-55	205.00
IUUC-Tme-126981	Tuber melanosporum	66.45	9.00e-48	180.00
IUUC-Ttr-128280	Tursiops truncatus	72.41	4.00e-36	140.00
IUUC-Uma-129582	Ustilago maydis	75.64	7.00e-73	263.00
IUUC-Vda-129845	Verticillium dahliae	73.20	1.00e-67	246.00
IUUC-Vpa-130242	Vicugna pacos	66.42	2.00e-54	202.00
IUUC-Vvi-130948	Vitis vinifera	60.90	9.00e-57	210.00
IUUC-Xtr-132540	Xenopus tropicalis	66.24	2.00e-62	229.00
IUUC-Xma-133885	Xiphophorus maculatus	64.97	3.00e-62	228.00
IUUC-Yli-134673	Yarrowia lipolytica	57.79	8.00e-56	207.00
IUUC-Zma-135055	Zea mays	60.13	7.00e-55	204.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence