iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mlu-067642

Ensembl Protein ID

ENSMLUP00000015858.2

UniProt Accession

G1PWR9; G1PWR9_MYOLU

Genbank Protein ID

ENSMLUP00000015858

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02003611

Gene Name

NGEF

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000017390.2	ENSMLUT00000017393.2	ENSMLUP00000015858.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.20e-10	41.2	614	669

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
           +vq  ++y aq+ deLtl+  d++ ++  ++++ gW+ g++   + rG fP+n +e++
   Q: 614  QVQCVHPYVAQQPDELTLELADILNIL--DKTEDGWIFGERLHDQERGWFPSNMTEEI 669
           6999***********************..9999*********************9987 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

METKDSDHLE KPQKKSVDGP WELADEPANV RPELLSEEEK MPQADLIQDK EPRYHNLIQR 60
NSIFNRTVRR RSKGKARNTP KSNAGHLADS PENGKSVKEL PALNFSQNRT PLWPIETQTD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGACCA AGGACTCTGA CCACTTGGAA AAGCCACAGA AAAAATCAGT GGATGGCCCC 60
TGGGAACTTG CTGATGAACC AGCCAACGTG AGACCTGAGT TACTCTCAGA AGAAGAGAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000219--DH-domain
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR001452--SH3_domain

PROSITE

PS50010--DH_2
PS50003--PH_DOMAIN
PS50002--SH3

Pfam

PF00169--PH
PF00621--RhoGEF
PF14604--SH3_9

SMART

SM00233--PH
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aca-005169	Anolis carolinensis	45.41	9.00e-99	354.00
IUUC-Bta-013108	Bos taurus	94.01	0.00e+00	1071.00
IUUC-Cin-025559	Ciona intestinalis	42.06	3.00e-27	113.00
IUUC-Eca-033839	Equus caballus	95.08	0.00e+00	1090.00
IUUC-Lch-049409	Latimeria chalumnae	44.13	1.00e-95	343.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence