iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ggo-044551

Ensembl Protein ID

ENSGGOP00000020469.1

UniProt Accession

G3RXD3; G3RXD3_GORGO

Protein Name

Uncharacterized protein

Gene Name

NWD1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000016341.2	ENSGGOT00000029771.1	ENSGGOP00000020469.1
ENSGGOG00000016341.2	ENSGGOT00000016406.2	ENSGGOP00000015952.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.80e-23	80.2	907	942
UBD/Beta-Prp	5.20e-48	164.2	861	1076

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtcla.f.sdtllvsGsdDgtikvWDlrtgv 34
           gHt++v+c++ f  +tl +s+s D t+++W+l +g+
   Q: 907  GHTGEVRCVKiFaKGTLAISASKDYTLRLWNLLSGR 942
           8********9558669***************99887 PP

UBD/Beta-Prp

   S: 46   rslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee. 131
           ++lsg+ +++ta+ +  ++k+lv g +D++  vwd++    +h l+gh+ +v++++++++g   +s+s+d t+r+w+l +g +  + 
   Q: 861  ATLSGCHKGITAMAWGVEEKLLVIGTQDGIMAVWDMEEQHVIHMLTGHTGEVRCVKIFAKGTLAISASKDYTLRLWNLLSGREKFTi 947
           799******************************************************************************999999 PP
   S: 132  ....tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgec 214
                +++ +  ++ ++v++  +++ s+s  ++++ W+l+t++l+ +  g+  d+  ++++  ++  l+++s+dg v lw+  tg+ 
   Q: 948  wdggSKNPAEPQIWNLHVDEAHKVVYSAS-GSKINAWNLETAELVFHILGDASDPWMCMAVLASQATLLAVSRDGVVSLWSSATGKL 1033
           99998999999999999999776666665.5789*************************************************9999 PP
   S: 215  vrtlnght...dnvksvrfspnderlvsgssDgsiriWdlrsg 254
             +++  +   +++++    +++  lv+g s gsi++  ++ +
   Q: 1034 QGKQHMSSikeETPTCAISVQKQGKLVTGFSNGSISLVSSKGD 1076
           8888876566666666666668888999999999988655555 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

TQRGKPCRAL PTLKQTFCQK HGLMFEILDL ALEIKILGTT KRQAASLLLM RMIHCTKVPF 60
VPSFLALIGD QYGPCLVPSR IDEKEWEVLR DHLTARPSDL ELVARYFRRD ENAVPPTYVL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACGCAGAGAG GGAAGCCCTG CAGAGCACTG CCTACCCTGA AGTGCAGACC TTCTGCCAGA 60
AGCATGGCTT GATGTTTGAG GTAACTGGAA GTCACTCCGG GCTCCATGCT TTTTTTTTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR027417--P-loop_NTPase
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001525	Ailuropoda melanoleuca	80.04	0.00e+00	2435.00
IUUC-Apl-003467	Anas platyrhynchos	54.43	3.00e-68	251.00
IUUC-Ame-011400	Astyanax mexicanus	35.40	0.00e+00	882.00
IUUC-Bta-013223	Bos taurus	80.76	0.00e+00	2147.00
IUUC-Cel-018404	Caenorhabditis elegans	27.30	7.00e-82	299.00
IUUC-Cja-018773	Callithrix jacchus	87.11	0.00e+00	1627.00
IUUC-Cfa-020334	Canis familiaris	80.56	0.00e+00	2427.00
IUUC-Cpo-022316	Cavia porcellus	63.62	0.00e+00	1827.00
IUUC-Csa-023631	Chlorocebus sabaeus	90.94	0.00e+00	2778.00
IUUC-Cin-025646	Ciona intestinalis	32.23	3.00e-130	459.00
IUUC-Csv-026191	Ciona savignyi	24.94	3.00e-26	112.00
IUUC-Dre-028241	Danio rerio	34.83	0.00e+00	847.00
IUUC-Dno-029990	Dasypus novemcinctus	71.43	4.00e-175	607.00
IUUC-Dor-030869	Dipodomys ordii	61.58	3.00e-173	602.00
IUUC-Ete-033059	Echinops telfairi	83.59	0.00e+00	852.00
IUUC-Eca-033718	Equus caballus	76.05	0.00e+00	2325.00
IUUC-Fca-035748	Felis catus	80.22	0.00e+00	2315.00
IUUC-Gac-041507	Gasterosteus aculeatus	33.61	0.00e+00	711.00
IUUC-Hsa-046787	Homo sapiens	94.13	0.00e+00	2913.00
IUUC-Itr-048104	Ictidomys tridecemlineatus	68.60	0.00e+00	1247.00
IUUC-Lch-049578	Latimeria chalumnae	45.39	0.00e+00	1334.00
IUUC-Loc-052039	Lepisosteus oculatus	39.45	0.00e+00	1115.00
IUUC-Laf-054240	Loxodonta africana	78.76	0.00e+00	2455.00
IUUC-Mcc-054657	Macaca mulatta	84.08	0.00e+00	2434.00
IUUC-Meu-056591	Macropus eugenii	62.24	0.00e+00	1141.00
IUUC-Mmr-061577	Microcebus murinus	76.83	0.00e+00	2356.00
IUUC-Mdo-062895	Monodelphis domestica	59.92	0.00e+00	1711.00
IUUC-Mmu-063866	Mus musculus	74.82	0.00e+00	2266.00
IUUC-Mpu-066510	Mustela putorius furo	79.46	0.00e+00	2435.00
IUUC-Mlu-067855	Myotis lucifugus	79.33	0.00e+00	2368.00
IUUC-Nle-069557	Nomascus leucogenys	86.78	0.00e+00	2614.00
IUUC-Opr-071196	Ochotona princeps	61.13	2.00e-177	616.00
IUUC-Ont-072070	Oreochromis niloticus	33.31	0.00e+00	704.00
IUUC-Oan-073437	Ornithorhynchus anatinus	55.57	0.00e+00	1200.00
IUUC-Ocu-074941	Oryctolagus cuniculus	80.00	1.00e-51	195.00
IUUC-Ola-086624	Oryzias latipes	32.49	0.00e+00	644.00
IUUC-Oga-088313	Otolemur garnettii	82.84	0.00e+00	2314.00
IUUC-Oar-090123	Ovis aries	78.62	0.00e+00	2400.00
IUUC-Ptr-090552	Pan troglodytes	93.47	0.00e+00	1218.00
IUUC-Psi-093963	Pelodiscus sinensis	52.07	0.00e+00	1508.00
IUUC-Pfo-096197	Poecilia formosa	32.76	0.00e+00	707.00
IUUC-Pab-097755	Pongo abelii	95.18	0.00e+00	1076.00
IUUC-Pca-100809	Procavia capensis	80.29	0.00e+00	1240.00
IUUC-Pva-102554	Pteropus vampyrus	77.89	0.00e+00	2155.00
IUUC-Rno-105174	Rattus norvegicus	68.82	0.00e+00	1989.00
IUUC-Sha-107304	Sarcophilus harrisii	58.66	0.00e+00	1817.00
IUUC-Sar-113168	Sorex araneus	63.96	0.00e+00	1343.00
IUUC-Tru-118251	Takifugu rubripes	34.62	0.00e+00	636.00
IUUC-Tsy-119276	Tarsius syrichta	77.17	2.00e-118	421.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence