iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ocu-074664

Ensembl Protein ID

ENSOCUP00000022468.1

UniProt Accession

G1TZE6; G1TZE6_RABIT

Genbank Protein ID

ENSOCUP00000022468

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAGW02060241

Gene Name

EFCAB8

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000027297.2	ENSOCUT00000024528.2	ENSOCUP00000022468.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.50e-22	77.3	309	334
UBD/Beta-Prp	2.00e-46	158.5	256	544

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 6    vtclaf.sd.tllvsGsdDgtikvWD 29
           + c+++ +d ++lv+G++D +i++W+
   Q: 309  ILCFDYcPDkNFLVTGGYDPNIRLWN 334
           889999*9*9***************9 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsr.dgtikvwdvttgkl....lrslsgheaevtavkfspdgkilvtgseDrtikvw.dlstgkcvht 89
           + h + ++ vkf+p+ +++++ s+ d++  v ++ + k+      s+ +  +++ + ++ pd+++lvtg+ D +i++w ++ + k+v  
   Q: 256  AIHHNWCQQVKFIPELNVVVSCSAiDRSSLVLSILPAKAsekpRLSMLNLRKGILCFDYCPDKNFLVTGGYDPNIRLWnPFVSQKPVWL 344
           55667777788888888777655324444455555544445454566777788999999999999999999999999955569999999 PP
   S: 90   lkghedsvlslsfsp.sgdklvsGshdrtirvwdletgqclee.............................................. 131
           +kgh+ sv+ + +s  s++ l+s s+d+ +rvwd++ + cl++                                              
   Q: 345  MKGHQTSVTHVMVSSkSSSILISISKDKNVRVWDMQDYICLQSfcgklfalgncpitsayfhseagalvcstfsigilkgyseaqgpvk 433
           99999999999999855699999999999999999999999999999999999999999999999999999999999999999999988 PP
   S: 132  ..tlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtl..tgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecv 215
               + h+ +  c+v+ ++  + +vsG+l +tv++W + tg+ + ++  +g+++   + +++d++ ++l++g + gt ++w++ +gec+
   Q: 434  agKITTHS-APLCAVLYSKIfKQVVSGCLHGTVNVWEITTGRKMVEFsvSGDQQVELTAMALDESERCLLTGLREGTMQMWNYNSGECL 521
           75445555.555555555566**************************88888888888999**************************** PP
   S: 216  rtlnghtdnvksvrfspnderlv 238
            t+ + ++   s   + n+++++
   Q: 522  LTFPNPDQLEISGIIHMNKTYYM 544
           ***99887666666665666655 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

LSLSEVMDLE AFIKTMKRVL SNASDDMLEA LFLKVDSDCN GFVTWQKYVD YMMGEFRGQE 60
EMRKSQYRLR FHLPMTVVPL NHGCEIVKVA FLKLRFKKIG CFLSISKDGL LQFWSESFSL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTTCTCTCT CTGAAGTCAT GGATTTGGAA GCTTTCATTA AGACCATGAA GAGGGTTCTG 60
AGCAATGCGT CAGATGACAT GCTGGAGGCA CTGTTTCTGA AGGTGGACTC AGACTGTAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR011992--EF-hand-dom_pair
IPR002048--EF_hand_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50222--EF_HAND_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005509--F:calcium ion binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cja-020006	Callithrix jacchus	71.33	0.00e+00	1055.00
IUUC-Cfa-020765	Canis familiaris	69.84	0.00e+00	1337.00
IUUC-Cin-025265	Ciona intestinalis	28.04	1.00e-70	261.00
IUUC-Dno-029238	Dasypus novemcinctus	64.55	0.00e+00	1215.00
IUUC-Dme-031984	Drosophila melanogaster	22.15	1.00e-47	185.00
IUUC-Gmo-039551	Gadus morhua	29.55	1.00e-27	117.00
IUUC-Ggo-044932	Gorilla gorilla	74.03	0.00e+00	1458.00
IUUC-Hsa-046963	Homo sapiens	73.39	0.00e+00	1450.00
IUUC-Lch-050281	Latimeria chalumnae	38.53	2.00e-153	535.00
IUUC-Loc-052029	Lepisosteus oculatus	40.44	9.00e-146	510.00
IUUC-Laf-054508	Loxodonta africana	75.40	0.00e+00	679.00
IUUC-Mcc-054635	Macaca mulatta	72.85	0.00e+00	1439.00
IUUC-Mmr-061370	Microcebus murinus	70.39	0.00e+00	1319.00
IUUC-Mdo-061862	Monodelphis domestica	52.05	0.00e+00	980.00
IUUC-Mmu-063271	Mus musculus	74.49	3.00e-160	557.00
IUUC-Mpu-066224	Mustela putorius furo	67.95	0.00e+00	1279.00
IUUC-Oar-089288	Ovis aries	68.38	0.00e+00	1320.00
IUUC-Psi-093985	Pelodiscus sinensis	40.96	2.00e-128	452.00
IUUC-Pfo-097353	Poecilia formosa	24.06	1.00e-44	174.00
IUUC-Smo-109247	Selaginella moellendorffii	24.86	1.00e-33	138.00
IUUC-Ssc-115233	Sus scrofa	74.88	6.00e-77	280.00
IUUC-Tni-120449	Tetraodon nigroviridis	29.24	2.00e-28	119.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence