iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mlu-068178

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02001496

Gene Name

USP38

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000013423.2	ENSMLUT00000013426.2	ENSMLUP00000012214.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.50e-81	274.2	491	996

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw..kskkkavsprellkalkkeaeefsgy 87
           tGl NlgNtCYmNSv+Q+L++ +++r+++l+ + + +n         +l+k+lq+lf+ l   ++k++a++pr +++a +   + f+  
   Q: 491  TGLINLGNTCYMNSVIQALFMATDFRRQVLSLNLNGCN---------SLMKKLQHLFAFLAhtQQKREAYAPRIFFEASR--PPWFTPR 568
           7******************************5555554.........7************97788999*********998..777**** PP
   S: 88   eqqDaqEflaflldqleeelkk...eknkpkeeeeeedkselsde........aeekkkkknkslisdlFqgqlksqikclecdnvssr 165
           +qqD++E+l+flld+l+ee k    +++++ +e+ +  +++l++         +   ++  +k+li+++F+g+l+++i cl+c+++s++
   Q: 569  SQQDCSEYLRFLLDRLHEEEKIlkvQSSHKPSESLGCIETSLQEVaskaavltETPYTNDGEKTLIEKMFGGKLRTHICCLNCRSTSQK 657
           *******************95566666666666666666666666888888877777777888************************** PP
   S: 166  eepfldlslpvpgkeetkke..................................................................... 185
            e f+dlsl++  +++++ +                                                                     
   Q: 658  VEAFTDLSLAFCPSSSMDSLsfqdpasslstpdggllgacpgpseepgiynpaaatfvydsvmnermlgsppdefcctentsvpsessk 746
           ************999887779******************************************************************** PP
   S: 186  .................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpl 257
                            s++d+L+ f ++e l+g+n+yyce+c ++q+aek++++++ Pe+Lil L Rfs++++ ++r+ki ++v++pl
   Q: 747  ifvnkdvpqkpggeatpSVTDLLNYFLAPEILTGDNQYYCENCASLQNAEKTMQITEEPEYLILTLLRFSYDQKYHVRRKILDNVSLPL 835
           ***************************************************************************************** PP
   S: 258  eLdlspfctspeekqke...............................kkkYeLiavvvHsG.slssGHYvayvkn............. 301
            L+l    t++ ++ +e                                + Y L++vvvHsG s++sGHY++y++n             
   Q: 836  VLELPVKRTTSFSSLSEswsidvdftdisenlakklkpsgteeaccpiLVPYLLSSVVVHSGvSSESGHYYSYARNitgtessyqmchq 924
           *999965555333333356666666666666677777777888888889**************************************** PP
   S: 302  ...............................ekgkWllfdDskVtevkeeevleetg....staYvlfYkrr 338
                                           +++W+lf+Ds+Vt ++ ++v++ t+    +taYvl+Y+++
   Q: 925  setlalassqshlltrdspsavieqdlenkeMSKEWFLFNDSRVTFTSFQSVQKITSrfpkDTAYVLLYRKQ 996
           *******9999999999999999988865544555*******************999************986 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

GGGGGGRSRC CRAPSSPPPR GPPAPPRGCL RPLPAPRPRG VATMDKILEG LVSSSYPLPV 60
KRVIVRKVVE SAEHWQDEAQ CQAMFDLTTR LILEGQDPFQ RQVGHQVLEA YARYHRPEFE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCGGCGGTG GCGGTGGTCG ATCCCGCTGC TGCCGCGCTC CAAGTTCACC TCCGCCCCGG 60
GGTCCTCCCG CCCCACCTCG GGGCTGTCTC CGCCCGCTCC CTGCCCCTCG GCCTCGCGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR033840--USP38
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002174	Ailuropoda melanoleuca	92.66	0.00e+00	1806.00
IUUC-Apl-003435	Anas platyrhynchos	75.88	0.00e+00	1238.00
IUUC-Aca-004556	Anolis carolinensis	70.17	0.00e+00	1237.00
IUUC-Ame-010616	Astyanax mexicanus	62.13	0.00e+00	1182.00
IUUC-Bta-013544	Bos taurus	91.50	0.00e+00	1765.00
IUUC-Cja-018745	Callithrix jacchus	89.97	0.00e+00	1784.00
IUUC-Cfa-020434	Canis familiaris	88.91	0.00e+00	1740.00
IUUC-Cpo-021666	Cavia porcellus	89.59	0.00e+00	1702.00
IUUC-Csa-023965	Chlorocebus sabaeus	91.79	0.00e+00	1849.00
IUUC-Cho-024809	Choloepus hoffmanni	82.99	0.00e+00	1221.00
IUUC-Cin-025604	Ciona intestinalis	37.77	7.00e-41	160.00
IUUC-Csv-026333	Ciona savignyi	44.07	2.00e-30	125.00
IUUC-Dre-028338	Danio rerio	62.24	0.00e+00	1182.00
IUUC-Dno-029372	Dasypus novemcinctus	90.07	0.00e+00	1768.00
IUUC-Dor-030752	Dipodomys ordii	88.46	0.00e+00	1213.00
IUUC-Ete-032588	Echinops telfairi	79.53	0.00e+00	1090.00
IUUC-Eca-034416	Equus caballus	92.95	0.00e+00	1864.00
IUUC-Eeu-035132	Erinaceus europaeus	72.46	0.00e+00	1343.00
IUUC-Fca-036137	Felis catus	92.73	0.00e+00	1816.00
IUUC-Fal-037297	Ficedula albicollis	74.81	0.00e+00	1399.00
IUUC-Gmo-038727	Gadus morhua	65.21	0.00e+00	991.00
IUUC-Gga-041091	Gallus gallus	73.55	0.00e+00	1346.00
IUUC-Gac-042082	Gasterosteus aculeatus	62.85	0.00e+00	1104.00
IUUC-Ggo-045376	Gorilla gorilla	86.65	0.00e+00	1699.00
IUUC-Hsa-046444	Homo sapiens	91.60	0.00e+00	1806.00
IUUC-Itr-047976	Ictidomys tridecemlineatus	90.32	0.00e+00	1813.00
IUUC-Lch-050500	Latimeria chalumnae	71.86	0.00e+00	1392.00
IUUC-Loc-052625	Lepisosteus oculatus	64.83	0.00e+00	1246.00
IUUC-Laf-053689	Loxodonta africana	91.55	0.00e+00	1793.00
IUUC-Mcc-055286	Macaca mulatta	91.88	0.00e+00	1808.00
IUUC-Mga-059905	Meleagris gallopavo	73.70	0.00e+00	1206.00
IUUC-Mmr-061397	Microcebus murinus	92.55	0.00e+00	1823.00
IUUC-Mdo-062833	Monodelphis domestica	84.95	0.00e+00	1708.00
IUUC-Mmu-063157	Mus musculus	88.44	0.00e+00	1745.00
IUUC-Mpu-066434	Mustela putorius furo	93.51	0.00e+00	1848.00
IUUC-Nle-070153	Nomascus leucogenys	91.31	0.00e+00	1768.00
IUUC-Opr-070454	Ochotona princeps	43.91	3.00e-64	240.00
IUUC-Ont-072330	Oreochromis niloticus	63.43	0.00e+00	1204.00
IUUC-Oan-072709	Ornithorhynchus anatinus	80.20	0.00e+00	1251.00
IUUC-Ocu-074832	Oryctolagus cuniculus	92.45	0.00e+00	1819.00
IUUC-Ola-087003	Oryzias latipes	55.67	5.00e-46	176.00
IUUC-Oga-088517	Otolemur garnettii	86.76	0.00e+00	1734.00
IUUC-Oar-089472	Ovis aries	87.61	0.00e+00	1701.00
IUUC-Ptr-090996	Pan troglodytes	91.21	0.00e+00	1800.00
IUUC-Pan-091837	Papio anubis	90.48	0.00e+00	1809.00
IUUC-Psi-093236	Pelodiscus sinensis	75.68	0.00e+00	1142.00
IUUC-Pma-094349	Petromyzon marinus	52.54	0.00e+00	920.00
IUUC-Pfo-097193	Poecilia formosa	62.56	0.00e+00	1120.00
IUUC-Pab-098710	Pongo abelii	91.60	0.00e+00	1823.00
IUUC-Pca-100794	Procavia capensis	80.44	0.00e+00	1551.00
IUUC-Pva-102722	Pteropus vampyrus	92.27	0.00e+00	1816.00
IUUC-Rno-105743	Rattus norvegicus	87.20	0.00e+00	1709.00
IUUC-Sha-106563	Sarcophilus harrisii	84.42	0.00e+00	1404.00
IUUC-Sar-113533	Sorex araneus	76.43	0.00e+00	1484.00
IUUC-Ssc-116259	Sus scrofa	82.76	0.00e+00	1534.00
IUUC-Tgu-117475	Taeniopygia guttata	75.11	0.00e+00	1293.00
IUUC-Tru-118623	Takifugu rubripes	62.87	0.00e+00	1122.00
IUUC-Tsy-119250	Tarsius syrichta	91.05	0.00e+00	1426.00
IUUC-Tni-120441	Tetraodon nigroviridis	59.34	0.00e+00	1040.00
IUUC-Tbe-127936	Tupaia belangeri	79.64	0.00e+00	1477.00
IUUC-Ttr-128483	Tursiops truncatus	79.14	0.00e+00	1375.00
IUUC-Vpa-130303	Vicugna pacos	92.76	0.00e+00	1018.00
IUUC-Xtr-132773	Xenopus tropicalis	71.09	0.00e+00	1345.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence