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Tag Content
UUCD2 ID IUUC-Cja-018950
UUCD1 version UUC-CaJ-01125
Ensembl Protein ID ENSCJAP00000043467.1
UniProt Accession F7I5L2; F7I5L2_CALJA
Genbank Protein ID JAB08759.1; JAB08760.1; JAB17199.1; JAB29875.1
Protein Name Ubiquitin carboxyl-terminal hydrolase 47
Genbank Nucleotide ID ACFV01053776; GAMT01003101; GAMS01005937; GAMR01004057
Gene Name USP47
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSCJAG00000010537.2 ENSCJAT00000058462.1 ENSCJAP00000043467.1
ENSCJAG00000010537.2 ENSCJAT00000020645.2 ENSCJAP00000019536.2
ENSCJAG00000010537.2 ENSCJAT00000020637.2 ENSCJAP00000019528.2
ENSCJAG00000010537.2 ENSCJAT00000060968.1 ENSCJAP00000046507.1
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 2.10e-75 255.0 100 474
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           +Gl N+  tCY+NS+LQ+L+++pe+r++l +    +++e++ ++p +++  +lq+lf  l++skk+a++++++++++++ ++e    +q
   Q: 100  VGLVNQAMTCYLNSLLQTLFMTPEFRNALYK---WEFEESE-EDPVTSIPYQLQRLFVLLQTSKKRAIETTDVTRSFGWDSSE--AWQQ 182
           6******************************...5555443.5899*********************************9998..9*** PP
   S: 90   qDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpg 178
           +D+qE++++++d+le++                           k++++ +li++l+qg+lk+ ++clec+ +  r ++ ld++l ++ 
   Q: 183  HDVQELCRVMFDALEQKW--------------------------KQTEQADLINELYQGKLKDYVRCLECGYEGWRIDTYLDIPLVIRP 245
           ******************..........................678999*************************************95 PP
   S: 179  ke.etkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfct 266
              +++  s++++L++f ++e l+g n+y+ce+ckkk++a+k l++ ++P  L+l+LkRf f+ ++++r+k+n++++fp+eLd+s f  
   Q: 246  YGsSQAFASVEEALHAFIQPEILDGPNQYFCERCKKKCDARKGLRFLHFPYLLTLQLKRFDFDYTTMHRIKLNDRMTFPEELDMSTFID 334
           54045678******************************************************************************999 PP
   S: 267  speekqke.....................................................kkkYeLiavvvHsGslssGHYvayvkne 302
            ++ek+ +                                                     + +YeL++v+vHsGs+ +GHY+a++k+ 
   Q: 335  VEDEKSPQtesctdsgaenegschsdqmsndfsnddgvdegicletnsgtekisksgleknSLIYELFSVMVHSGSAAGGHYYACIKSF 423
           9777666678888888888888889999999999999999999999999999999999999***************************6 PP
   S: 303  kgk.WllfdDskVtevkeeevleetg................staYvlfYk 336
           +++ W+ f+D++V+ +++e++++++g                ++aY+l+Y+
   Q: 424  SDEqWYSFNDQHVSRITQEDIKKTHGgssgsrgyyssafassTNAYMLIYR 474
           5555*******************888************************8 PP
   
Organism Callithrix jacchus
Protein Sequence
(Fasta)
MVPGEENQLV PKEAPLDHTS DKSLLDANFE PGKKNFLHLT DKDGEQPQML LEDSSAGEDS 60
VHDRFIGPLP REGSVGSTSD YVSQSYSYSS ILNKSETGYV GLVNQAMTCY LNSLLQTLFM 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Cja-018950|DUB,USP|Callithrix jacchus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GAGGGGAAAA GGACGTCTGC AGAGTGAACA GGAGCAAATA AAACGCGGTC CATTCCGGCT 60
GGAAGGGCCA GAGCCGTGTC TAAGGGCGGA GGCCGGGAGG TGGTCCGCGA TGGTGTCTCT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Cja-018950|DUB,USP|Callithrix jacchus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-1185--Reference proteome
Interpro

IPR001394--Peptidase_C19_UCH
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom
IPR018200--USP_CS
IPR028889--USP_dom
PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
Pfam

PF14560--Ubiquitin_2
PF00443--UCH
Gene Ontology

GO:0005737--C:cytoplasm
GO:0019005--C:SCF ubiquitin ligase complex
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0006284--P:base-excision repair
GO:0034644--P:cellular response to UV
GO:0035520--P:monoubiquitinated protein deubiquitination
GO:0043154--P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0010972--P:negative regulation of G2/M transition of mitotic cell cycle
GO:1902230--P:negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0030307--P:positive regulation of cell growth
GO:0042493--P:response to drug
GO:0006511--P:ubiquitin-dependent protein catabolic process
KEGG cjc:100393344
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002228 Ailuropoda melanoleuca 96.79 0.00e+00 2360.00
IUUC-Apl-003486 Anas platyrhynchos 90.77 0.00e+00 2214.00
IUUC-Aca-005061 Anolis carolinensis 88.35 0.00e+00 2227.00
IUUC-Ame-011206 Astyanax mexicanus 80.80 0.00e+00 1978.00
IUUC-Bta-012942 Bos taurus 97.57 0.00e+00 2397.00
IUUC-Cel-018600 Caenorhabditis elegans 37.72 2.00e-122 434.00
IUUC-Cfa-020299 Canis familiaris 98.67 0.00e+00 2417.00
IUUC-Cpo-021943 Cavia porcellus 97.57 0.00e+00 2370.00
IUUC-Csa-023285 Chlorocebus sabaeus 99.61 0.00e+00 2413.00
IUUC-Cho-025006 Choloepus hoffmanni 91.76 0.00e+00 2078.00
IUUC-Cin-025145 Ciona intestinalis 41.45 0.00e+00 731.00
IUUC-Csv-025839 Ciona savignyi 49.62 3.00e-166 579.00
IUUC-Dre-027959 Danio rerio 81.31 0.00e+00 1919.00
IUUC-Dno-030023 Dasypus novemcinctus 95.07 0.00e+00 2255.00
IUUC-Dor-030994 Dipodomys ordii 97.72 0.00e+00 967.00
IUUC-Dme-031604 Drosophila melanogaster 49.39 3.00e-148 520.00
IUUC-Ete-032596 Echinops telfairi 81.41 0.00e+00 1317.00
IUUC-Eca-033913 Equus caballus 98.20 0.00e+00 2407.00
IUUC-Eeu-034518 Erinaceus europaeus 90.11 0.00e+00 2148.00
IUUC-Fca-035997 Felis catus 98.35 0.00e+00 2404.00
IUUC-Fal-037088 Ficedula albicollis 89.73 0.00e+00 2106.00
IUUC-Gmo-038920 Gadus morhua 77.29 0.00e+00 1863.00
IUUC-Gga-040953 Gallus gallus 89.96 0.00e+00 2199.00
IUUC-Gac-042400 Gasterosteus aculeatus 79.80 0.00e+00 1914.00
IUUC-Ggo-044820 Gorilla gorilla 96.63 0.00e+00 2364.00
IUUC-Hsa-046634 Homo sapiens 99.45 0.00e+00 2407.00
IUUC-Lch-050440 Latimeria chalumnae 86.73 0.00e+00 2152.00
IUUC-Loc-051904 Lepisosteus oculatus 85.23 0.00e+00 2083.00
IUUC-Laf-053760 Loxodonta africana 96.94 0.00e+00 2403.00
IUUC-Mcc-054637 Macaca mulatta 99.61 0.00e+00 2412.00
IUUC-Meu-056904 Macropus eugenii 95.60 0.00e+00 1699.00
IUUC-Mga-059556 Meleagris gallopavo 89.33 0.00e+00 2187.00
IUUC-Mmr-061192 Microcebus murinus 98.98 0.00e+00 2398.00
IUUC-Mdo-061929 Monodelphis domestica 95.39 0.00e+00 2352.00
IUUC-Mmu-063726 Mus musculus 94.90 0.00e+00 2361.00
IUUC-Mpu-066014 Mustela putorius furo 98.51 0.00e+00 2412.00
IUUC-Mlu-067232 Myotis lucifugus 97.65 0.00e+00 2375.00
IUUC-Nle-069619 Nomascus leucogenys 99.45 0.00e+00 2410.00
IUUC-Opr-070224 Ochotona princeps 93.58 0.00e+00 1152.00
IUUC-Ont-071384 Oreochromis niloticus 81.16 0.00e+00 1943.00
IUUC-Oan-073208 Ornithorhynchus anatinus 89.25 0.00e+00 2233.00
IUUC-Ocu-074285 Oryctolagus cuniculus 98.43 0.00e+00 2388.00
IUUC-Ola-087051 Oryzias latipes 79.63 0.00e+00 1866.00
IUUC-Oga-088928 Otolemur garnettii 98.35 0.00e+00 2390.00
IUUC-Oar-090215 Ovis aries 97.96 0.00e+00 2407.00
IUUC-Ptr-091035 Pan troglodytes 99.45 0.00e+00 2409.00
IUUC-Pan-092377 Papio anubis 99.06 0.00e+00 2390.00
IUUC-Pfo-096722 Poecilia formosa 80.64 0.00e+00 1927.00
IUUC-Pab-098723 Pongo abelii 99.37 0.00e+00 2407.00
IUUC-Pca-100105 Procavia capensis 92.46 0.00e+00 2179.00
IUUC-Pva-102514 Pteropus vampyrus 98.47 0.00e+00 776.00
IUUC-Rno-105384 Rattus norvegicus 95.92 0.00e+00 2318.00
IUUC-Sha-106982 Sarcophilus harrisii 93.48 0.00e+00 2344.00
IUUC-Sar-113723 Sorex araneus 87.08 0.00e+00 937.00
IUUC-Ssc-115671 Sus scrofa 98.06 0.00e+00 2055.00
IUUC-Tgu-116722 Taeniopygia guttata 88.98 0.00e+00 2177.00
IUUC-Tru-118380 Takifugu rubripes 78.48 0.00e+00 1936.00
IUUC-Tsy-119646 Tarsius syrichta 91.60 0.00e+00 2178.00
IUUC-Tni-120762 Tetraodon nigroviridis 78.83 0.00e+00 1946.00
IUUC-Tbe-127861 Tupaia belangeri 95.92 0.00e+00 2283.00
IUUC-Ttr-129254 Tursiops truncatus 92.28 0.00e+00 1463.00
IUUC-Vpa-130141 Vicugna pacos 91.91 0.00e+00 1143.00
IUUC-Xtr-132700 Xenopus tropicalis 82.67 0.00e+00 2064.00
Created Date 25-Jun-2017

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