iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pma-094230

Ensembl Protein ID

ENSPMAP00000000934.1

UniProt Accession

S4R6V4; S4R6V4_PETMA

Protein Name

Tyrosine-protein kinase

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPMAG00000000844.1	ENSPMAT00000000938.1	ENSPMAP00000000934.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	7.90e-12	44.2	2	62

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvk.......elegkrGlfPenFvekl 62
            +lydy++ ++++L++k+G+ ++v   ++++ +W++++k       e  + rG +P+n+v++ 
   Q: 2    VALYDYDGRTNEDLSFKEGELLEVT--DKTNSDWWYAQKktastsnERYNTRGYIPANYVAEY 62
           58**********************7..999************999999999*********975 PP

Organism

Petromyzon marinus

Protein Sequence
(Fasta)

YVALYDYDGR TNEDLSFKEG ELLEVTDKTN SDWWYAQKKT ASTSNERYNT RGYIPANYVA 60
EYQSLDAEPW FFGDIKRADA EKYLLADVNT TGAFLIRQSE SRKTDYSLSV RDGSTVKHYR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TACGTGGCCC TCTACGACTA CGACGGACGA ACAAACGAGG ATCTGAGCTT CAAGGAGGGC 60
GAACTCCTCG AGGTGACGGA CAAGACGAAC TCGGACTGGT GGTACGCGCA GAAGAAGACG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003394	Anas platyrhynchos	57.68	3.00e-156	543.00
IUUC-Aca-004553	Anolis carolinensis	58.66	4.00e-163	566.00
IUUC-Cel-018682	Caenorhabditis elegans	53.73	3.00e-148	516.00
IUUC-Cja-019885	Callithrix jacchus	62.26	2.00e-173	600.00
IUUC-Cin-025605	Ciona intestinalis	57.98	4.00e-158	549.00
IUUC-Dre-028274	Danio rerio	58.66	3.00e-162	563.00
IUUC-Dno-029689	Dasypus novemcinctus	61.62	3.00e-168	583.00
IUUC-Dme-031976	Drosophila melanogaster	64.64	2.00e-179	620.00
IUUC-Eeu-034770	Erinaceus europaeus	51.51	4.00e-114	403.00
IUUC-Fal-036892	Ficedula albicollis	59.55	4.00e-160	556.00
IUUC-Gga-041072	Gallus gallus	59.61	1.00e-159	554.00
IUUC-Loc-052913	Lepisosteus oculatus	60.74	3.00e-166	576.00
IUUC-Mga-059456	Meleagris gallopavo	58.32	6.00e-157	545.00
IUUC-Mmr-061480	Microcebus murinus	63.03	7.00e-169	585.00
IUUC-Mlu-067167	Myotis lucifugus	59.57	6.00e-159	552.00
IUUC-Nle-069786	Nomascus leucogenys	61.61	1.00e-172	597.00
IUUC-Ont-072417	Oreochromis niloticus	60.35	5.00e-169	585.00
IUUC-Ola-086419	Oryzias latipes	59.22	9.00e-166	575.00
IUUC-Pan-092732	Papio anubis	62.04	3.00e-172	596.00
IUUC-Psi-093899	Pelodiscus sinensis	62.47	2.00e-174	603.00
IUUC-Pfo-096035	Poecilia formosa	58.39	2.00e-163	567.00
IUUC-Rno-105269	Rattus norvegicus	62.61	1.00e-171	594.00
IUUC-Tgu-116491	Taeniopygia guttata	59.20	6.00e-161	558.00
IUUC-Tru-117795	Takifugu rubripes	55.16	2.00e-153	534.00
IUUC-Tni-120512	Tetraodon nigroviridis	59.48	4.00e-168	583.00
IUUC-Ttr-128817	Tursiops truncatus	61.74	3.00e-171	593.00
IUUC-Vpa-130389	Vicugna pacos	59.60	5.00e-156	542.00
IUUC-Xtr-132360	Xenopus tropicalis	55.89	3.00e-158	550.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence