iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSG00000175575.12	ENST00000310571.7	ENSP00000311665.3
ENSG00000175575.12	ENST00000536003.5	ENSP00000438124.1
ENSG00000175575.12	ENST00000546039.5	ENSP00000439877.1
ENSG00000175575.12	ENST00000536582.5	ENSP00000443473.1
ENSG00000175575.12	ENST00000544909.5	ENSP00000438071.1
ENSG00000175575.12	ENST00000540659.1	ENSP00000442434.1

Annotation

Cancer Mutation
TCGA	ICGC	COSMIC	CGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	TCGA	ICGC
COSMIC	THPA	HPM
DNA & RNA Element
UTRdb	circBase	circRNADb	CircNet
miRTarBase	microRNA	TRANSFAC	RepTar
SomamiR	miRcode	RAID2
Protein-protein Interaction
HINT	InWeb_IM
Disease-associated Variation
GWASdb
Post-translational Modifications (PTMs)
CPLM	BioGRID
DNA Methylation
TCGA	ICGC
Protein Expression/Proteomics
THPA	HPM	GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	9.40e-17	62.1	175	206

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDl 30
           gH++++ + a    ++ +vs+s+Dgt ++WD 
   Q: 175  GHKGGILDTAIvdRGRNVVSASRDGTARLWDC 206
           899999999997544779*************6 PP

Organism

Homo sapiens

Protein Sequence
(Fasta)

MLELKPSSVD SKFSTTMQAY VFPRCFGTAW VLTSFFPSYS DLDTVFITSN MIANFCCEPA 60
EWVQTKSIHI SCPKENASSK FLAPYTTFSR IHTKSITCLD ISSRGGLGVS SSTDGTMKIW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GATCGCAGCC CCGTTGTGCC CGCAACGCCT CCTGAAGAAC GCGGTACGCG ATGCTCACCG 60
AACAGGTGGG AGAAGAGGGC CCGAACGCAC GCTCCTACGC GGCGGCTTGG GTTTCGCAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002247	Ailuropoda melanoleuca	94.86	2.00e-178	618.00
IUUC-Apl-003653	Anas platyrhynchos	78.61	4.00e-146	510.00
IUUC-Aca-004747	Anolis carolinensis	79.15	2.00e-162	565.00
IUUC-Ago-007984	Ashbya gossypii	30.13	2.00e-23	103.00
IUUC-Bta-013482	Bos taurus	94.26	1.00e-178	619.00
IUUC-Cel-018693	Caenorhabditis elegans	28.67	6.00e-29	122.00
IUUC-Cja-018842	Callithrix jacchus	95.47	1.00e-179	622.00
IUUC-Cfa-020708	Canis familiaris	94.56	3.00e-178	617.00
IUUC-Cpo-021469	Cavia porcellus	94.26	2.00e-178	618.00
IUUC-Csa-024109	Chlorocebus sabaeus	96.68	1.00e-180	625.00
IUUC-Cin-025576	Ciona intestinalis	42.42	7.00e-76	277.00
IUUC-Dno-029167	Dasypus novemcinctus	92.75	8.00e-175	606.00
IUUC-Dor-030470	Dipodomys ordii	66.78	5.00e-107	380.00
IUUC-Ete-033078	Echinops telfairi	74.83	4.00e-59	221.00
IUUC-Eca-034292	Equus caballus	82.28	7.00e-151	526.00
IUUC-Eeu-035251	Erinaceus europaeus	91.87	3.00e-169	587.00
IUUC-Fca-035982	Felis catus	94.26	1.00e-178	619.00
IUUC-Fal-036938	Ficedula albicollis	84.78	2.00e-157	548.00
IUUC-Gga-040796	Gallus gallus	83.99	2.00e-159	555.00
IUUC-Ggo-044448	Gorilla gorilla	82.47	2.00e-107	382.00
IUUC-Itr-048359	Ictidomys tridecemlineatus	93.59	0.00e+00	666.00
IUUC-Lch-050291	Latimeria chalumnae	63.20	2.00e-123	436.00
IUUC-Loc-052254	Lepisosteus oculatus	72.51	6.00e-146	510.00
IUUC-Laf-053334	Loxodonta africana	93.96	6.00e-176	610.00
IUUC-Mcc-055257	Macaca mulatta	97.28	0.00e+00	627.00
IUUC-Meu-056613	Macropus eugenii	88.00	2.00e-123	434.00
IUUC-Mga-059647	Meleagris gallopavo	84.29	7.00e-161	560.00
IUUC-Mmr-061119	Microcebus murinus	95.47	7.00e-180	623.00
IUUC-Mdo-062819	Monodelphis domestica	82.60	1.00e-161	562.00
IUUC-Mpu-066654	Mustela putorius furo	94.88	3.00e-179	621.00
IUUC-Mlu-067875	Myotis lucifugus	94.86	4.00e-178	617.00
IUUC-Nle-069290	Nomascus leucogenys	97.28	0.00e+00	633.00
IUUC-Opr-070348	Ochotona princeps	76.13	1.00e-143	502.00
IUUC-Oan-072693	Ornithorhynchus anatinus	80.13	2.00e-147	515.00
IUUC-Ocu-074103	Oryctolagus cuniculus	93.41	5.00e-175	607.00
IUUC-Oga-089096	Otolemur garnettii	93.41	0.00e+00	670.00
IUUC-Oar-089389	Ovis aries	94.56	9.00e-179	619.00
IUUC-Ptr-090483	Pan troglodytes	97.89	0.00e+00	634.00
IUUC-Pan-091915	Papio anubis	96.17	6.00e-93	333.00
IUUC-Psi-093034	Pelodiscus sinensis	82.23	7.00e-154	536.00
IUUC-Pab-097969	Pongo abelii	97.58	0.00e+00	633.00
IUUC-Pca-100381	Procavia capensis	93.71	4.00e-177	613.00
IUUC-Pva-103127	Pteropus vampyrus	94.86	2.00e-118	419.00
IUUC-Sce-106259	Saccharomyces cerevisiae	30.49	2.00e-25	110.00
IUUC-Sha-106604	Sarcophilus harrisii	88.52	5.00e-170	590.00
IUUC-Sar-113535	Sorex araneus	90.69	5.00e-162	563.00
IUUC-Ssc-115947	Sus scrofa	94.26	1.00e-176	612.00
IUUC-Tgu-117085	Taeniopygia guttata	84.29	3.00e-131	461.00
IUUC-Tsy-119428	Tarsius syrichta	93.29	3.00e-78	285.00
IUUC-Tbe-127687	Tupaia belangeri	61.49	1.00e-40	160.00
IUUC-Ttr-129277	Tursiops truncatus	93.92	3.00e-89	322.00
IUUC-Vpa-130349	Vicugna pacos	82.18	5.00e-145	507.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence