iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Laf-054193

Ensembl Protein ID

ENSLAFP00000028469.1

UniProt Accession

G3UKW0; G3UKW0_LOXAF

Protein Name

Uncharacterized protein

Gene Name

KIF21B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000016500.3	ENSLAFT00000016506.3	ENSLAFP00000013863.3
ENSLAFG00000016500.3	ENSLAFT00000029246.1	ENSLAFP00000028469.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.20e-29	100.6	1529	1563
UBD/Beta-Prp	3.60e-42	144.9	1395	1600

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgv 34
           H+d+v++laf ++ ++l+s+++ g+ikvW+++ ++
   Q: 1529 HKDWVCALAFvPGrPMLLSACRAGVIKVWNVDNFT 1563
           ***********999****************98765 PP

UBD/Beta-Prp

   S: 50   gheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp...sgdklvsGshdrtirvwdletgqclee.. 131
           + e +++++ +sp+g +++ +++ +++++w+ls ++++ +l+gh   v++l++s+     d +v+Gs+d +++ ++l  g+c+    
   Q: 1395 QGEHQINQIALSPSG-TMLYAASGNAVRIWELSRFQPIGKLTGHIGPVMCLTVSQtssHHDLVVTGSKDHYVKTFEL--GECVMGtv 1478
           45668*********9.99*************************************874449**************55..77887778 PP
   S: 132  .....tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtge 213
                ++ +h + + c+++++  ++l+sGs D+ ++ Wdl++++l+++   +h+d v  l+f + ++ l+s+ + g +k+w++ + +
   Q: 1479 gpthnFEPPHYDGIECLAIQG--DILFSGSRDNGIKKWDLEQQELIQQIPNAHKDWVCALAFVPGRPMLLSACRAGVIKVWNVDNFT 1563
           9999999**************..**************************999*********************************** PP
   S: 214  cvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlr 252
            + + +gh+++++ + +   ++++ ++ssD ++++W +r
   Q: 1564 PIGEIKGHDSPINAICTN--TKHIFTASSDLTVKFWSVR 1600
           *************87777..****************876 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

RIRPQLSKEK IEGCHICTSV TPGEPQVLLG KDKAFTYDFV FDLDTWQEQI YSTCVNKLIE 60
GCFEGYNATV LAYGQTGAGK TYTMGTGFDM ATSEDEQGII PRAISHLFTG IAERKRRAQE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCAGGCC AAGGGGACTG CTGTGTCAAG GTGGCCGTCA GGTAGGGACC TGGGGCGGCA 60
GGGAGTGCAT GGAGGGGGCT GAGGCTTTGT CTCGCGTGGG CGCGGGGCCC CGGGAGCGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0505--Motor protein
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR011072--HR1_rho-bd
IPR019821--Kinesin_motor_CS
IPR001752--Kinesin_motor_dom
IPR027417--P-loop_NTPase
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00411--KINESIN_MOTOR_1
PS50067--KINESIN_MOTOR_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00225--Kinesin
PF00400--WD40

PRINTS

PR00380--KINESINHEAVY

SMART

SM00129--KISc
SM00320--WD40

Gene Ontology

GO:0005524--F:ATP binding
GO:0003777--F:microtubule motor activity
GO:0007018--P:microtubule-based movement

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001279	Ailuropoda melanoleuca	87.29	0.00e+00	2519.00
IUUC-Aca-004506	Anolis carolinensis	74.48	0.00e+00	1437.00
IUUC-Ame-011515	Astyanax mexicanus	69.32	0.00e+00	1297.00
IUUC-Bta-013185	Bos taurus	70.17	0.00e+00	1161.00
IUUC-Cja-018844	Callithrix jacchus	84.12	0.00e+00	2440.00
IUUC-Cfa-021187	Canis familiaris	87.05	0.00e+00	2480.00
IUUC-Cpo-022444	Cavia porcellus	85.24	0.00e+00	2498.00
IUUC-Csa-023852	Chlorocebus sabaeus	87.11	0.00e+00	2497.00
IUUC-Cin-025160	Ciona intestinalis	42.69	8.00e-83	300.00
IUUC-Dre-027839	Danio rerio	69.34	0.00e+00	1308.00
IUUC-Dno-030058	Dasypus novemcinctus	83.93	0.00e+00	2478.00
IUUC-Dor-030673	Dipodomys ordii	82.33	0.00e+00	2291.00
IUUC-Ete-032705	Echinops telfairi	75.05	0.00e+00	764.00
IUUC-Eca-033885	Equus caballus	85.96	0.00e+00	2438.00
IUUC-Eeu-035338	Erinaceus europaeus	76.44	0.00e+00	1055.00
IUUC-Fca-035388	Felis catus	86.49	0.00e+00	2318.00
IUUC-Fal-037044	Ficedula albicollis	78.71	0.00e+00	2350.00
IUUC-Gmo-039034	Gadus morhua	61.95	0.00e+00	1089.00
IUUC-Gac-041328	Gasterosteus aculeatus	68.12	0.00e+00	1312.00
IUUC-Ggo-045392	Gorilla gorilla	86.75	0.00e+00	2484.00
IUUC-Hsa-046713	Homo sapiens	87.29	0.00e+00	2501.00
IUUC-Itr-049068	Ictidomys tridecemlineatus	88.22	0.00e+00	1480.00
IUUC-Loc-052703	Lepisosteus oculatus	71.15	0.00e+00	2165.00
IUUC-Mcc-055484	Macaca mulatta	85.96	0.00e+00	2478.00
IUUC-Meu-056278	Macropus eugenii	81.32	0.00e+00	1106.00
IUUC-Mga-059816	Meleagris gallopavo	75.91	0.00e+00	2241.00
IUUC-Mmr-061071	Microcebus murinus	84.33	0.00e+00	2429.00
IUUC-Mdo-062845	Monodelphis domestica	82.53	0.00e+00	2425.00
IUUC-Mmu-063967	Mus musculus	85.91	0.00e+00	2434.00
IUUC-Mpu-066448	Mustela putorius furo	85.53	0.00e+00	2467.00
IUUC-Nle-070037	Nomascus leucogenys	87.36	0.00e+00	1630.00
IUUC-Opr-070325	Ochotona princeps	82.02	0.00e+00	2299.00
IUUC-Ont-071851	Oreochromis niloticus	66.11	0.00e+00	2004.00
IUUC-Oan-073615	Ornithorhynchus anatinus	79.37	0.00e+00	2206.00
IUUC-Ocu-073855	Oryctolagus cuniculus	86.34	0.00e+00	2461.00
IUUC-Ola-086703	Oryzias latipes	67.85	0.00e+00	1298.00
IUUC-Oga-088171	Otolemur garnettii	85.76	0.00e+00	2529.00
IUUC-Oar-089693	Ovis aries	77.69	0.00e+00	1132.00
IUUC-Ptr-090535	Pan troglodytes	86.46	0.00e+00	1594.00
IUUC-Pan-091917	Papio anubis	86.89	0.00e+00	2329.00
IUUC-Psi-093752	Pelodiscus sinensis	75.49	0.00e+00	1258.00
IUUC-Pfo-096827	Poecilia formosa	65.60	0.00e+00	1243.00
IUUC-Pab-098441	Pongo abelii	87.29	0.00e+00	2512.00
IUUC-Pca-100781	Procavia capensis	85.09	0.00e+00	778.00
IUUC-Pva-103099	Pteropus vampyrus	81.71	0.00e+00	1201.00
IUUC-Rno-105872	Rattus norvegicus	85.49	0.00e+00	2453.00
IUUC-Sha-107097	Sarcophilus harrisii	81.41	0.00e+00	2377.00
IUUC-Ssc-115638	Sus scrofa	85.33	0.00e+00	2172.00
IUUC-Tgu-116504	Taeniopygia guttata	77.34	0.00e+00	1470.00
IUUC-Tru-118242	Takifugu rubripes	67.05	0.00e+00	1300.00
IUUC-Ttr-128824	Tursiops truncatus	80.49	0.00e+00	1968.00
IUUC-Xtr-131798	Xenopus tropicalis	58.36	0.00e+00	1654.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence