iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-050239

Ensembl Protein ID

ENSLACP00000018713.1

UniProt Accession

H3B9Z2; H3B9Z2_LATCH

Genbank Protein ID

ENSLACP00000018713

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

AFYH01067713

Gene Name

YES1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000016474.1	ENSLACT00000018846.1	ENSLACP00000018713.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.00e-15	56.7	92	147

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           + +lydyea ++d+L++kkG+  ++i  ++++++W+++ +  +gk+G +P+n+v+ ++
   Q: 92   FVALYDYEARTTDDLSFKKGERFQII--NNTEGDWWEARSISTGKKGYIPSNYVAPAD 147
           789***********************..8999**********************9875 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

MGCIKSKEDK GGSFKYRTDN PSDSISTHVG HYGPDPTQVS QAQSSKGPSA NFNSHSMTPF 60
GGSSGMTPFG GASFAVVQSQ YPAGMTGGVT IFVALYDYEA RTTDDLSFKK GERFQIINNT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGAGGAGGA GGAGGAACTG TTGGAGCTTT CATTCGGGGG GAAAGGAGCG TGCACTTATC 60
GTTTTGTTTT TCCACATAAC TTCAACACTA TTCTTTCATT TTTTTTTTGA AGGGGGGGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0034334--P:adherens junction maintenance
GO:0060027--P:convergent extension involved in gastrulation
GO:0046777--P:protein autophosphorylation
GO:0045859--P:regulation of protein kinase activity

KEGG

lcm:102349447

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002374	Ailuropoda melanoleuca	89.30	0.00e+00	998.00
IUUC-Apl-004032	Anas platyrhynchos	91.50	0.00e+00	1016.00
IUUC-Aca-004255	Anolis carolinensis	91.13	0.00e+00	1033.00
IUUC-Ame-010954	Astyanax mexicanus	87.59	0.00e+00	1003.00
IUUC-Bta-013503	Bos taurus	89.09	0.00e+00	971.00
IUUC-Bol-016049	Brassica oleracea	32.95	4.00e-17	83.60
IUUC-Cja-019694	Callithrix jacchus	88.21	0.00e+00	973.00
IUUC-Cfa-020402	Canis familiaris	89.28	0.00e+00	1000.00
IUUC-Cpo-022506	Cavia porcellus	88.72	0.00e+00	987.00
IUUC-Csa-023713	Chlorocebus sabaeus	88.95	0.00e+00	981.00
IUUC-Cin-025390	Ciona intestinalis	72.89	0.00e+00	669.00
IUUC-Csv-026029	Ciona savignyi	64.58	0.00e+00	648.00
IUUC-Dre-027978	Danio rerio	88.28	0.00e+00	978.00
IUUC-Dno-029897	Dasypus novemcinctus	88.45	0.00e+00	881.00
IUUC-Dor-030202	Dipodomys ordii	94.91	0.00e+00	906.00
IUUC-Eca-034157	Equus caballus	88.35	0.00e+00	988.00
IUUC-Eeu-034950	Erinaceus europaeus	84.38	2.00e-166	577.00
IUUC-Fca-036233	Felis catus	90.57	0.00e+00	1029.00
IUUC-Fal-037461	Ficedula albicollis	91.13	0.00e+00	1037.00
IUUC-Gmo-038929	Gadus morhua	84.15	0.00e+00	929.00
IUUC-Gga-041107	Gallus gallus	91.87	0.00e+00	1020.00
IUUC-Gac-042321	Gasterosteus aculeatus	85.61	0.00e+00	970.00
IUUC-Hsa-047010	Homo sapiens	88.95	0.00e+00	993.00
IUUC-Loc-052314	Lepisosteus oculatus	90.09	0.00e+00	983.00
IUUC-Laf-053517	Loxodonta africana	88.35	0.00e+00	966.00
IUUC-Mcc-055626	Macaca mulatta	88.95	0.00e+00	982.00
IUUC-Meu-056155	Macropus eugenii	76.27	0.00e+00	724.00
IUUC-Mga-059310	Meleagris gallopavo	91.87	0.00e+00	1020.00
IUUC-Mmr-061652	Microcebus murinus	88.91	0.00e+00	989.00
IUUC-Mdo-062963	Monodelphis domestica	88.54	0.00e+00	1000.00
IUUC-Mmu-064128	Mus musculus	88.54	0.00e+00	1003.00
IUUC-Mpu-065906	Mustela putorius furo	89.09	0.00e+00	998.00
IUUC-Mlu-067035	Myotis lucifugus	88.42	0.00e+00	989.00
IUUC-Nle-069041	Nomascus leucogenys	84.90	0.00e+00	933.00
IUUC-Opr-070299	Ochotona princeps	79.85	0.00e+00	866.00
IUUC-Ont-072337	Oreochromis niloticus	86.47	0.00e+00	971.00
IUUC-Oan-072997	Ornithorhynchus anatinus	96.26	0.00e+00	921.00
IUUC-Ocu-074171	Oryctolagus cuniculus	89.09	0.00e+00	993.00
IUUC-Ola-086619	Oryzias latipes	85.12	0.00e+00	976.00
IUUC-Oga-087957	Otolemur garnettii	87.80	0.00e+00	974.00
IUUC-Oar-089670	Ovis aries	89.09	0.00e+00	978.00
IUUC-Ptr-091352	Pan troglodytes	88.95	0.00e+00	994.00
IUUC-Pan-092202	Papio anubis	88.95	0.00e+00	982.00
IUUC-Psi-093310	Pelodiscus sinensis	91.68	0.00e+00	1046.00
IUUC-Pma-094232	Petromyzon marinus	86.41	0.00e+00	863.00
IUUC-Pfo-096137	Poecilia formosa	84.63	0.00e+00	956.00
IUUC-Pab-098301	Pongo abelii	93.40	0.00e+00	934.00
IUUC-Pva-102592	Pteropus vampyrus	85.03	0.00e+00	938.00
IUUC-Rno-105544	Rattus norvegicus	88.91	0.00e+00	981.00
IUUC-Sar-113364	Sorex araneus	85.58	0.00e+00	917.00
IUUC-Tgu-117380	Taeniopygia guttata	91.13	0.00e+00	1037.00
IUUC-Tru-117594	Takifugu rubripes	85.51	0.00e+00	971.00
IUUC-Tni-120433	Tetraodon nigroviridis	84.99	0.00e+00	962.00
IUUC-Ttr-128893	Tursiops truncatus	88.35	0.00e+00	988.00
IUUC-Vpa-130060	Vicugna pacos	89.09	0.00e+00	983.00
IUUC-Xtr-132322	Xenopus tropicalis	90.39	0.00e+00	1018.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence