iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cja-019394

UUCD1 version

UUC-CaJ-00003

Ensembl Protein ID

ENSCJAP00000000747.2

UniProt Accession

H9KVK7; H9KVK7_CALJA

Protein Name

Uncharacterized protein

Gene Name

TRIM6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCJAG00000000439.2	ENSCJAT00000000798.2	ENSCJAP00000000747.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	2.50e-09	38.4	15	60

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkw.pglknssskefrCPlCr 46
           C+iCl+ + + pl+l+CgH f++ Cl       ++  + +e +CP+C+
   Q: 15   CPICLDLLTE-PLSLDCGHSFCQACLtR-NsRESMTGQEGERSCPVCQ 60
           ********99.***************53.44789999**********7 PP

Organism

Callithrix jacchus

Protein Sequence
(Fasta)

MTSTVLVDIQ EEATCPICLD LLTEPLSLDC GHSFCQACLT RNSRESMTGQ EGERSCPVCQ 60
TSYQLGNLRP NRHLAKIAGR LREEVLGAGK QLKAVLCADY GEKLQLFKDD GKVICWLCER 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACTTCAA CAGTACTGGT GGACATACAG GAAGAGGCGA CCTGCCCCAT CTGCCTGGAC 60
CTTCTGACAG AACCCCTGAG CTTAGACTGC GGCCACAGCT TCTGCCAAGC CTGCCTCACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR027370--Znf-RING_LisH
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13445--zf-RING_UBOX

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00184--RING

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0035458--P:cellular response to interferon-beta
GO:0098586--P:cellular response to virus
GO:0010994--P:free ubiquitin chain polymerization
GO:2000737--P:negative regulation of stem cell differentiation
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0045071--P:negative regulation of viral genome replication
GO:0002741--P:positive regulation of cytokine secretion involved in immune response
GO:0002230--P:positive regulation of defense response to virus by host
GO:0010628--P:positive regulation of gene expression
GO:0033138--P:positive regulation of peptidyl-serine phosphorylation
GO:0010800--P:positive regulation of peptidyl-threonine phosphorylation
GO:2000679--P:positive regulation of transcription regulatory region DNA binding
GO:0060340--P:positive regulation of type I interferon-mediated signaling pathway
GO:0000209--P:protein polyubiquitination
GO:0070206--P:protein trimerization
GO:0032496--P:response to lipopolysaccharide

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aly-006134	Arabidopsis lyrata	35.94	4.00e-07	48.90
IUUC-Hsa-046006	Homo sapiens	69.88	2.00e-148	518.00
IUUC-Kpa-049392	Komagataella pastoris	31.37	6.00e-10	58.20
IUUC-Mor-056977	Magnaporthe oryzae	61.76	5.00e-06	47.00
IUUC-Ptr-090573	Pan troglodytes	69.88	2.00e-148	518.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence