iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pab-098124

Ensembl Protein ID

ENSPPYP00000005752.2

UniProt Accession

H2NIX5; H2NIX5_PONAB

Genbank Protein ID

ENSPPYP00000005752

Protein Name

E3 ubiquitin-protein ligase RNF34

Genbank Nucleotide ID

ABGA01350403

Gene Name

RNF34

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000005049.2	ENSPPYT00000005972.2	ENSPPYP00000005752.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	86.32	1.00e-163	572.00	IUUC-Rno-105481

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Pongo abelii

Protein Sequence
(Fasta)

MRKASATSMW ASCCGLLNEV MGTGAVRGQQ SGFAGATGPF RFTPNPEFST YPPAATEGPN 60
IVCKACGLSF SVFRKKHVCC DCKKDFCSVC SVLQENLRRC STCHLLQETA FQRPQLMRLK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGGGGGAGT GGTGCTAAGG ATCAAGTATA CTGTTAAAAG AAAACAAAAA CCCAAGCATG 60
AGGAAGGTAA CATTTATATC TATAGCACAC GTTATTGTAA TAATCTATCA GTTTGGCCAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003034--SAP_dom
IPR011011--Znf_FYVE_PHD
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016604--C:nuclear body
GO:0005886--C:plasma membrane
GO:1901981--F:phosphatidylinositol phosphate binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0070417--P:cellular response to cold
GO:2001271--P:negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis
GO:1902042--P:negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:1901797--P:negative regulation of signal transduction by p53 class mediator
GO:0035872--P:nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0070936--P:protein K48-linked ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:2000374--P:regulation of oxygen metabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002341	Ailuropoda melanoleuca	90.64	4.00e-170	590.00
IUUC-Apl-003398	Anas platyrhynchos	75.13	1.00e-136	479.00
IUUC-Aca-005050	Anolis carolinensis	67.30	7.00e-79	286.00
IUUC-Bta-012886	Bos taurus	91.44	1.00e-173	602.00
IUUC-Cja-019045	Callithrix jacchus	96.50	0.00e+00	627.00
IUUC-Cfa-020037	Canis familiaris	88.17	3.00e-156	544.00
IUUC-Cpo-021618	Cavia porcellus	79.25	2.00e-142	498.00
IUUC-Csa-023303	Chlorocebus sabaeus	95.23	0.00e+00	641.00
IUUC-Cho-024671	Choloepus hoffmanni	84.28	2.00e-170	591.00
IUUC-Dre-027887	Danio rerio	60.73	7.00e-101	360.00
IUUC-Dno-029136	Dasypus novemcinctus	91.37	0.00e+00	632.00
IUUC-Dor-030596	Dipodomys ordii	85.44	3.00e-154	537.00
IUUC-Ete-032684	Echinops telfairi	87.30	4.00e-148	517.00
IUUC-Eca-033598	Equus caballus	91.78	2.00e-176	610.00
IUUC-Eeu-034878	Erinaceus europaeus	90.88	2.00e-173	601.00
IUUC-Fca-036370	Felis catus	89.24	1.00e-171	595.00
IUUC-Fal-036937	Ficedula albicollis	75.54	4.00e-133	467.00
IUUC-Gga-040411	Gallus gallus	75.00	1.00e-130	459.00
IUUC-Gac-042281	Gasterosteus aculeatus	61.68	3.00e-111	394.00
IUUC-Ggo-044752	Gorilla gorilla	98.66	0.00e+00	647.00
IUUC-Hsa-046299	Homo sapiens	98.92	0.00e+00	644.00
IUUC-Itr-047907	Ictidomys tridecemlineatus	89.89	4.00e-171	593.00
IUUC-Lch-049616	Latimeria chalumnae	66.06	8.00e-107	380.00
IUUC-Loc-052099	Lepisosteus oculatus	60.90	2.00e-117	415.00
IUUC-Laf-054103	Loxodonta africana	85.87	9.00e-165	572.00
IUUC-Mcc-055295	Macaca mulatta	95.73	0.00e+00	637.00
IUUC-Mga-059584	Meleagris gallopavo	74.46	4.00e-130	457.00
IUUC-Mmr-061766	Microcebus murinus	92.35	0.00e+00	630.00
IUUC-Mdo-062738	Monodelphis domestica	74.22	1.00e-134	473.00
IUUC-Mmu-064403	Mus musculus	88.27	8.00e-159	553.00
IUUC-Mpu-066021	Mustela putorius furo	90.11	7.00e-176	609.00
IUUC-Mlu-067144	Myotis lucifugus	90.59	2.00e-165	575.00
IUUC-Nle-070133	Nomascus leucogenys	98.87	5.00e-175	606.00
IUUC-Opr-070683	Ochotona princeps	82.97	2.00e-163	568.00
IUUC-Ont-072065	Oreochromis niloticus	60.65	2.00e-106	378.00
IUUC-Oan-073504	Ornithorhynchus anatinus	80.11	4.00e-145	507.00
IUUC-Ocu-074382	Oryctolagus cuniculus	88.44	8.00e-173	599.00
IUUC-Ola-087022	Oryzias latipes	60.26	5.00e-111	394.00
IUUC-Oga-087963	Otolemur garnettii	90.81	0.00e+00	639.00
IUUC-Oar-089439	Ovis aries	90.64	1.00e-171	595.00
IUUC-Ptr-091616	Pan troglodytes	98.38	0.00e+00	630.00
IUUC-Pan-092754	Papio anubis	95.74	0.00e+00	641.00
IUUC-Psi-093217	Pelodiscus sinensis	70.41	2.00e-120	425.00
IUUC-Pca-100954	Procavia capensis	90.37	2.00e-179	621.00
IUUC-Pva-102588	Pteropus vampyrus	90.37	6.00e-172	596.00
IUUC-Pte-104027	Pyrenophora teres	31.51	2.00e-08	55.50
IUUC-Rno-105481	Rattus norvegicus	86.32	4.00e-161	560.00
IUUC-Sha-106640	Sarcophilus harrisii	80.86	3.00e-143	501.00
IUUC-Sit-110649	Setaria italica	39.66	1.00e-08	52.00
IUUC-Sar-113331	Sorex araneus	91.64	4.00e-175	607.00
IUUC-Tgu-117252	Taeniopygia guttata	74.33	8.00e-131	459.00
IUUC-Tru-118556	Takifugu rubripes	59.84	2.00e-111	395.00
IUUC-Tsy-118891	Tarsius syrichta	65.26	2.00e-66	246.00
IUUC-Tni-119741	Tetraodon nigroviridis	57.59	5.00e-105	374.00
IUUC-Tbe-127380	Tupaia belangeri	91.89	0.00e+00	629.00
IUUC-Ttr-128999	Tursiops truncatus	89.87	9.00e-175	605.00
IUUC-Vpa-130168	Vicugna pacos	78.38	1.00e-90	325.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence