iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCJAG00000002419.2	ENSCJAT00000057799.1	ENSCJAP00000045411.1
ENSCJAG00000002419.2	ENSCJAT00000004709.1	ENSCJAP00000004468.1
ENSCJAG00000002419.2	ENSCJAT00000004667.1	ENSCJAP00000004430.1
ENSCJAG00000002419.2	ENSCJAT00000004716.1	ENSCJAP00000004475.1
ENSCJAG00000002419.2	ENSCJAT00000004723.1	ENSCJAP00000004482.1
ENSCJAG00000002419.2	ENSCJAT00000004705.2	ENSCJAP00000004464.2
ENSCJAG00000002419.2	ENSCJAT00000053674.1	ENSCJAP00000047520.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.90e-14	54.1	1108	1141

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclafsd.tl.lvsGsdDgtikvWDlrtg 33
           gH++ +t +   d t+ l+sG+ Dg i +WD+ tg
   Q: 1108 GHSGAITTVYI-DqTMvLASGGQDGAICLWDVLTG 1141
           8********88.446648*************9887 PP

Organism

Callithrix jacchus

Protein Sequence
(Fasta)

MTLTERLREK ISRAFYNHGL LCASYPIPII LFTGFCILAC CYPLLKLPLP GTGPVEFTTP 60
VKDYSPPPVD SDHKQGEPAE QPEWYVGAPV AYVQQIFVKS SVFPWHKNLL AVDVFRSPLS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCGGCGGCC AGAAGGGAGA GGGCGGGCGC TACGCACCGG ACTGCGGGCC GGGAGCGCGC 60
ACGCCGCGCT CCGCCCCCGC CGCCGCCTCA GTCGCCGTCG CTGCCGCCGC CCAGGAGCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0677--Repeat
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0853--WD repeat

Interpro

IPR011047--Quinoprotein_ADH-like_supfam
IPR030225--SCAP
IPR000731--SSD
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50156--SSD
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12349--Sterol-sensing
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0000139--C:Golgi membrane
GO:0016021--C:integral component of membrane
GO:0015485--F:cholesterol binding
GO:0008203--P:cholesterol metabolic process
GO:0045540--P:regulation of cholesterol biosynthetic process
GO:0042304--P:regulation of fatty acid biosynthetic process
GO:0001666--P:response to hypoxia
GO:0032868--P:response to insulin
GO:0032933--P:SREBP signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001802	Ailuropoda melanoleuca	91.02	0.00e+00	1023.00
IUUC-Apl-003294	Anas platyrhynchos	74.42	0.00e+00	1662.00
IUUC-Aca-004424	Anolis carolinensis	68.03	0.00e+00	1451.00
IUUC-Bta-013478	Bos taurus	90.86	0.00e+00	2022.00
IUUC-Cel-018160	Caenorhabditis elegans	27.93	5.00e-57	216.00
IUUC-Cfa-021082	Canis familiaris	88.98	0.00e+00	1959.00
IUUC-Cpo-022477	Cavia porcellus	83.00	0.00e+00	1826.00
IUUC-Csa-023176	Chlorocebus sabaeus	92.57	0.00e+00	2065.00
IUUC-Cin-025490	Ciona intestinalis	37.88	2.00e-89	323.00
IUUC-Csv-026115	Ciona savignyi	35.87	3.00e-119	423.00
IUUC-Dre-028008	Danio rerio	66.38	0.00e+00	1459.00
IUUC-Dno-028887	Dasypus novemcinctus	87.80	0.00e+00	1130.00
IUUC-Dor-030467	Dipodomys ordii	87.91	0.00e+00	800.00
IUUC-Dme-032087	Drosophila melanogaster	31.67	4.00e-99	356.00
IUUC-Ete-032372	Echinops telfairi	75.29	0.00e+00	1648.00
IUUC-Eca-033896	Equus caballus	91.25	0.00e+00	2097.00
IUUC-Eeu-035099	Erinaceus europaeus	91.82	0.00e+00	941.00
IUUC-Fca-035616	Felis catus	84.70	0.00e+00	1877.00
IUUC-Fal-037231	Ficedula albicollis	72.21	0.00e+00	1583.00
IUUC-Gmo-039439	Gadus morhua	63.57	0.00e+00	803.00
IUUC-Gac-041516	Gasterosteus aculeatus	65.65	0.00e+00	1440.00
IUUC-Hsa-046674	Homo sapiens	95.54	0.00e+00	2236.00
IUUC-Itr-048879	Ictidomys tridecemlineatus	90.93	0.00e+00	2078.00
IUUC-Lch-049689	Latimeria chalumnae	69.35	0.00e+00	1627.00
IUUC-Loc-052417	Lepisosteus oculatus	53.03	5.00e-133	468.00
IUUC-Laf-053795	Loxodonta africana	88.73	0.00e+00	2009.00
IUUC-Mcc-055502	Macaca mulatta	95.54	0.00e+00	2181.00
IUUC-Mga-059805	Meleagris gallopavo	75.45	0.00e+00	1671.00
IUUC-Mmr-060997	Microcebus murinus	91.88	0.00e+00	2124.00
IUUC-Mdo-062940	Monodelphis domestica	79.85	0.00e+00	1754.00
IUUC-Mmu-063255	Mus musculus	89.76	0.00e+00	2038.00
IUUC-Mpu-066158	Mustela putorius furo	90.15	0.00e+00	2024.00
IUUC-Mlu-067201	Myotis lucifugus	86.23	0.00e+00	1971.00
IUUC-Nle-069145	Nomascus leucogenys	94.88	0.00e+00	1340.00
IUUC-Opr-070797	Ochotona princeps	86.40	0.00e+00	1900.00
IUUC-Ont-071553	Oreochromis niloticus	64.90	0.00e+00	1437.00
IUUC-Ocu-074598	Oryctolagus cuniculus	91.95	0.00e+00	2030.00
IUUC-Ola-086650	Oryzias latipes	84.09	1.00e-111	395.00
IUUC-Oar-089287	Ovis aries	82.39	0.00e+00	1030.00
IUUC-Pan-092004	Papio anubis	95.27	0.00e+00	2160.00
IUUC-Psi-093028	Pelodiscus sinensis	69.79	0.00e+00	1451.00
IUUC-Pma-094145	Petromyzon marinus	51.16	0.00e+00	1087.00
IUUC-Pfo-096320	Poecilia formosa	65.24	0.00e+00	1436.00
IUUC-Pab-097862	Pongo abelii	95.78	0.00e+00	2231.00
IUUC-Pca-100862	Procavia capensis	76.43	0.00e+00	1573.00
IUUC-Pva-103050	Pteropus vampyrus	89.49	0.00e+00	1254.00
IUUC-Rno-105852	Rattus norvegicus	90.38	0.00e+00	2068.00
IUUC-Sha-107312	Sarcophilus harrisii	79.85	0.00e+00	1766.00
IUUC-Sar-113311	Sorex araneus	89.66	0.00e+00	859.00
IUUC-Ssc-116356	Sus scrofa	90.70	0.00e+00	2081.00
IUUC-Tgu-116896	Taeniopygia guttata	60.17	2.00e-149	523.00
IUUC-Tru-118197	Takifugu rubripes	66.26	0.00e+00	1440.00
IUUC-Tni-119823	Tetraodon nigroviridis	63.56	0.00e+00	1419.00
IUUC-Ttr-129164	Tursiops truncatus	91.25	0.00e+00	2034.00
IUUC-Xtr-132819	Xenopus tropicalis	66.79	0.00e+00	1548.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence