iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mlu-067201

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02049080

Gene Name

SCAP

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000004086.2	ENSMLUT00000004092.2	ENSMLUP00000003729.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.90e-15	55.1	1118	1151

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclafsd.tl.lvsGsdDgtikvWDlrtg 33
           gH++ +t++   d t+ l+sG+ Dg i +WD+ tg
   Q: 1118 GHSGAITAVYI-DqTMvLASGGQDGAICLWDVLTG 1151
           8********88.446648*************9887 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

MTLTDRLREK ISLAFYRHGL LCASHPVPIT LFTGLCILAC CYPLLKLPLP GTGPVEFTTP 60
VKDYSPPPVA PDPTPGEPSE RPEWYVGPPV AYVQQILVKS SVSPWHKDLL ARGRVPLPSV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACCCTGA CTGACAGGCT GCGTGAGAAG ATCTCGCTGG CCTTCTACCG CCACGGGCTG 60
CTCTGCGCCT CCCACCCCGT CCCCATCACC CTCTTCACGG GGCTCTGCAT CCTCGCCTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0677--Repeat
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0853--WD repeat

Interpro

IPR011047--Quinoprotein_ADH-like_supfam
IPR030225--SCAP
IPR000731--SSD
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50156--SSD
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12349--Sterol-sensing
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0000139--C:Golgi membrane
GO:0016021--C:integral component of membrane
GO:0015485--F:cholesterol binding
GO:0008203--P:cholesterol metabolic process
GO:0045540--P:regulation of cholesterol biosynthetic process
GO:0042304--P:regulation of fatty acid biosynthetic process
GO:0001666--P:response to hypoxia
GO:0032868--P:response to insulin
GO:0032933--P:SREBP signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001802	Ailuropoda melanoleuca	89.52	0.00e+00	989.00
IUUC-Apl-003294	Anas platyrhynchos	73.65	0.00e+00	1639.00
IUUC-Aca-004424	Anolis carolinensis	67.61	0.00e+00	1431.00
IUUC-Bta-013478	Bos taurus	87.70	0.00e+00	1955.00
IUUC-Cel-018160	Caenorhabditis elegans	29.65	1.00e-58	222.00
IUUC-Cja-019123	Callithrix jacchus	86.23	0.00e+00	1887.00
IUUC-Cfa-021082	Canis familiaris	87.24	0.00e+00	1912.00
IUUC-Cpo-022477	Cavia porcellus	81.37	0.00e+00	1792.00
IUUC-Csa-023176	Chlorocebus sabaeus	85.68	0.00e+00	1886.00
IUUC-Cin-025490	Ciona intestinalis	37.77	2.00e-85	310.00
IUUC-Csv-026115	Ciona savignyi	36.47	6.00e-123	435.00
IUUC-Dre-028008	Danio rerio	66.15	0.00e+00	1455.00
IUUC-Dno-028887	Dasypus novemcinctus	85.56	0.00e+00	1089.00
IUUC-Dor-030467	Dipodomys ordii	85.50	0.00e+00	769.00
IUUC-Dme-032087	Drosophila melanogaster	32.73	4.00e-99	356.00
IUUC-Ete-032372	Echinops telfairi	77.00	0.00e+00	1194.00
IUUC-Eca-033896	Equus caballus	88.25	0.00e+00	2063.00
IUUC-Eeu-035099	Erinaceus europaeus	79.83	0.00e+00	1075.00
IUUC-Fca-035616	Felis catus	88.47	0.00e+00	996.00
IUUC-Fal-037231	Ficedula albicollis	71.83	0.00e+00	1575.00
IUUC-Gmo-039439	Gadus morhua	71.95	5.00e-178	619.00
IUUC-Gac-041516	Gasterosteus aculeatus	66.34	0.00e+00	1439.00
IUUC-Hsa-046674	Homo sapiens	88.49	0.00e+00	2019.00
IUUC-Itr-048879	Ictidomys tridecemlineatus	87.17	0.00e+00	1970.00
IUUC-Lch-049689	Latimeria chalumnae	67.61	0.00e+00	1550.00
IUUC-Loc-052417	Lepisosteus oculatus	51.83	4.00e-128	451.00
IUUC-Laf-053795	Loxodonta africana	86.22	0.00e+00	1935.00
IUUC-Mcc-055502	Macaca mulatta	88.79	0.00e+00	2006.00
IUUC-Mga-059805	Meleagris gallopavo	74.50	0.00e+00	1654.00
IUUC-Mmr-060997	Microcebus murinus	87.57	0.00e+00	1999.00
IUUC-Mdo-062940	Monodelphis domestica	78.08	0.00e+00	1716.00
IUUC-Mmu-063255	Mus musculus	86.54	0.00e+00	1949.00
IUUC-Mpu-066158	Mustela putorius furo	88.33	0.00e+00	2010.00
IUUC-Nle-069145	Nomascus leucogenys	88.93	0.00e+00	1228.00
IUUC-Opr-070797	Ochotona princeps	82.04	0.00e+00	1798.00
IUUC-Ont-071553	Oreochromis niloticus	65.36	0.00e+00	1440.00
IUUC-Ocu-074598	Oryctolagus cuniculus	87.63	0.00e+00	1947.00
IUUC-Ola-086650	Oryzias latipes	84.23	2.00e-113	400.00
IUUC-Oar-089287	Ovis aries	80.52	0.00e+00	1004.00
IUUC-Pan-092004	Papio anubis	88.39	0.00e+00	1977.00
IUUC-Psi-093028	Pelodiscus sinensis	69.01	0.00e+00	1431.00
IUUC-Pma-094145	Petromyzon marinus	50.40	0.00e+00	1056.00
IUUC-Pfo-096320	Poecilia formosa	64.91	0.00e+00	1439.00
IUUC-Pab-097862	Pongo abelii	88.79	0.00e+00	2028.00
IUUC-Pca-100862	Procavia capensis	74.98	0.00e+00	1564.00
IUUC-Pva-103050	Pteropus vampyrus	87.87	0.00e+00	1255.00
IUUC-Rno-105852	Rattus norvegicus	87.16	0.00e+00	1969.00
IUUC-Sha-107312	Sarcophilus harrisii	78.31	0.00e+00	1734.00
IUUC-Sar-113311	Sorex araneus	86.17	0.00e+00	845.00
IUUC-Ssc-116356	Sus scrofa	87.87	0.00e+00	2030.00
IUUC-Tgu-116896	Taeniopygia guttata	58.64	1.00e-149	524.00
IUUC-Tru-118197	Takifugu rubripes	65.73	0.00e+00	1445.00
IUUC-Tni-119823	Tetraodon nigroviridis	63.79	0.00e+00	1430.00
IUUC-Ttr-129164	Tursiops truncatus	87.87	0.00e+00	1957.00
IUUC-Xtr-132819	Xenopus tropicalis	67.44	0.00e+00	1557.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence