iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-052625

Ensembl Protein ID

ENSLOCP00000010992.1

UniProt Accession

W5MRI3; W5MRI3_LEPOC

Genbank Protein ID

ENSLOCP00000010992

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHAT01015433

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000009016.1	ENSLOCT00000011008.1	ENSLOCP00000010992.1
ENSLOCG00000009016.1	ENSLOCT00000011022.1	ENSLOCP00000011006.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	4.20e-79	266.3	444	947

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           tGl NlgNtCYmNS++Q+L++ +++r+ +l+    +ln +      ++l+k+lq lf+ l ++++ a++pr++++a +   + f+  +q
   Q: 444  TGLINLGNTCYMNSIIQSLFMATDFRRSVLS---LNLNGS------NTLMKKLQLLFAFLAHTQRAAYAPRSFVEATR--PPWFTPGSQ 521
           7******************************...666665......59***************************998..777****** PP
   S: 90   qDaqEflaflldqleeelkk...............eknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvs 163
           qD++E+l+flld+l+ee k                 +n    ++ + d  + s++ ++ ++  +++li+++F+g+l+++i+c +c+++s
   Q: 522  QDCSEYLRFLLDRLHEEEKTmqalnlgkpllgsidDSNGLALKTPGMD--DHSSDGSSGEHGNKETLIENMFGGKLSTSIRCMQCNSIS 608
           ******************777888777777776443333333333333..444446677888889************************ PP
   S: 164  sreepfldlslpvpgkeetkke.................................................................sl 187
           ++eepf+dlsl+++   e+ ++                                                                 s+
   Q: 609  NKEEPFTDLSLAFRPLGENILPrsppsatisdtsdtgadagqglnttrqgsvsggsefegcstdaqkqaltdsdklaadkqdtgipiSV 697
           **************88876555899**************************************************************** PP
   S: 188  qdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfcts......... 267
            d+++ f ++e l+ +nkyycekc ++q aek++++ + Pe+Lil L Rfs++ + ++r+ki ++v +pl L+l    ++         
   Q: 698  PDLINYFLAPEILDADNKYYCEKCASLQCAEKTMQIIEAPEYLILTLLRFSYDAKCHVRRKILDNVVIPLFLQLPV-RHKtavrtsavp 785
           ***********************************************************************99984.333358889999 PP
   S: 268  .................................peekqkekkkYeLiavvvHsG.slssGHYvayvkn..................... 301
                                            +eek+++  +Y L++vv+HsG s++sGHY++y +n                     
   Q: 786  tgagsscsssplhvdspesgenlakklkpsrkeDEEKEDQVMSYLLSSVVMHSGmSSESGHYYSYGRNvtntdcclppglcyqgedtqd 874
           999999999999999999999999999998887444445599*********************************************** PP
   S: 302  ................................ekgkWllfdDskVtevkeeevleetg....staYvlfYkrr 338
                                           + ++W+lf+Ds+Vt ++  +v++ t+    +taY+l+Y+++
   Q: 875  ftlsglqddlngtassglpctslatqevdvapTAKDWFLFNDSRVTFTSFRSVQNVTSrfpkDTAYILIYRKQ 947
           ************999999999999998888877888*******************999************986 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

MDKILEGLVS SSHPVQVKKA IVKMVVEAAE KDITEEQCQA LYHLATRLIL SEDAFQRQVG 60
AQVLEAYARY HRGEFERFFC KDFILGLLQQ GYGPLDRKDP AIVDYIHGGL RLLISCPSVL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCTGTTGT TTCTCTAAAG TCGTCCATCG CCGTGCTGTA GACCCCCCAC TATGGATAAG 60
ATCCTGGAAG GCCTGGTGAG CTCCTCCCAC CCTGTGCAGG TGAAAAAGGC CATTGTAAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR001394--Peptidase_C19_UCH
IPR033840--USP38
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002174	Ailuropoda melanoleuca	64.46	0.00e+00	1222.00
IUUC-Apl-003435	Anas platyrhynchos	64.64	0.00e+00	1046.00
IUUC-Aca-004556	Anolis carolinensis	61.36	0.00e+00	1113.00
IUUC-Ame-010616	Astyanax mexicanus	67.22	0.00e+00	1349.00
IUUC-Bta-013544	Bos taurus	64.78	0.00e+00	1236.00
IUUC-Cja-018745	Callithrix jacchus	63.01	0.00e+00	1238.00
IUUC-Cfa-020434	Canis familiaris	64.14	0.00e+00	1217.00
IUUC-Cpo-021666	Cavia porcellus	64.48	0.00e+00	1194.00
IUUC-Csa-023965	Chlorocebus sabaeus	64.41	0.00e+00	1277.00
IUUC-Cho-024809	Choloepus hoffmanni	56.71	0.00e+00	796.00
IUUC-Cin-025604	Ciona intestinalis	29.95	3.00e-41	162.00
IUUC-Dre-028338	Danio rerio	66.89	0.00e+00	1366.00
IUUC-Dno-029372	Dasypus novemcinctus	65.39	0.00e+00	1262.00
IUUC-Dor-030752	Dipodomys ordii	61.08	0.00e+00	770.00
IUUC-Dme-031871	Drosophila melanogaster	26.31	1.00e-58	221.00
IUUC-Ete-032588	Echinops telfairi	55.49	0.00e+00	729.00
IUUC-Eca-034416	Equus caballus	64.74	0.00e+00	1273.00
IUUC-Eeu-035132	Erinaceus europaeus	52.32	0.00e+00	927.00
IUUC-Fca-036137	Felis catus	65.45	0.00e+00	1280.00
IUUC-Fal-037297	Ficedula albicollis	63.91	0.00e+00	1206.00
IUUC-Gmo-038727	Gadus morhua	72.88	0.00e+00	1113.00
IUUC-Gga-041091	Gallus gallus	63.63	0.00e+00	1168.00
IUUC-Gac-042082	Gasterosteus aculeatus	70.59	0.00e+00	1280.00
IUUC-Ggo-045376	Gorilla gorilla	60.73	0.00e+00	1155.00
IUUC-Hsa-046444	Homo sapiens	64.39	0.00e+00	1277.00
IUUC-Itr-047976	Ictidomys tridecemlineatus	63.93	0.00e+00	1268.00
IUUC-Lch-050500	Latimeria chalumnae	66.67	0.00e+00	1306.00
IUUC-Laf-053689	Loxodonta africana	64.19	0.00e+00	1257.00
IUUC-Mcc-055286	Macaca mulatta	64.16	0.00e+00	1266.00
IUUC-Mga-059905	Meleagris gallopavo	62.92	0.00e+00	1020.00
IUUC-Mmr-061397	Microcebus murinus	65.14	0.00e+00	1228.00
IUUC-Mdo-062833	Monodelphis domestica	65.51	0.00e+00	1315.00
IUUC-Mmu-063157	Mus musculus	63.92	0.00e+00	1214.00
IUUC-Mpu-066434	Mustela putorius furo	64.90	0.00e+00	1275.00
IUUC-Mlu-068178	Myotis lucifugus	64.84	0.00e+00	1210.00
IUUC-Nle-070153	Nomascus leucogenys	63.94	0.00e+00	1206.00
IUUC-Ont-072330	Oreochromis niloticus	68.53	0.00e+00	1363.00
IUUC-Oan-072709	Ornithorhynchus anatinus	64.56	0.00e+00	989.00
IUUC-Ocu-074832	Oryctolagus cuniculus	65.86	0.00e+00	1241.00
IUUC-Ola-087003	Oryzias latipes	62.74	4.00e-54	203.00
IUUC-Oga-088517	Otolemur garnettii	66.20	0.00e+00	1078.00
IUUC-Oar-089472	Ovis aries	63.70	0.00e+00	1157.00
IUUC-Ptr-090996	Pan troglodytes	64.30	0.00e+00	1274.00
IUUC-Pan-091837	Papio anubis	63.32	0.00e+00	1230.00
IUUC-Psi-093236	Pelodiscus sinensis	64.59	0.00e+00	947.00
IUUC-Pma-094349	Petromyzon marinus	51.91	0.00e+00	959.00
IUUC-Pfo-097193	Poecilia formosa	67.72	0.00e+00	1294.00
IUUC-Pab-098710	Pongo abelii	64.36	0.00e+00	1301.00
IUUC-Pca-100794	Procavia capensis	56.83	0.00e+00	1060.00
IUUC-Pva-102722	Pteropus vampyrus	64.60	0.00e+00	1270.00
IUUC-Rno-105743	Rattus norvegicus	64.55	0.00e+00	1208.00
IUUC-Sha-106563	Sarcophilus harrisii	64.23	0.00e+00	1048.00
IUUC-Sar-113533	Sorex araneus	58.71	0.00e+00	1083.00
IUUC-Ssc-116259	Sus scrofa	79.84	0.00e+00	823.00
IUUC-Tgu-117475	Taeniopygia guttata	63.15	0.00e+00	1099.00
IUUC-Tru-118623	Takifugu rubripes	68.83	0.00e+00	1275.00
IUUC-Tsy-119250	Tarsius syrichta	62.98	0.00e+00	939.00
IUUC-Tni-120441	Tetraodon nigroviridis	64.82	0.00e+00	1210.00
IUUC-Tbe-127936	Tupaia belangeri	55.57	0.00e+00	938.00
IUUC-Ttr-128483	Tursiops truncatus	54.59	0.00e+00	876.00
IUUC-Vpa-130303	Vicugna pacos	80.71	0.00e+00	890.00
IUUC-Xtr-132773	Xenopus tropicalis	63.83	0.00e+00	1229.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence