iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-049956

Ensembl Protein ID

ENSLACP00000016968.1

UniProt Accession

H3B4Z7; H3B4Z7_LATCH

Genbank Protein ID

ENSLACP00000016968

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AFYH01075618

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000014943.1	ENSLACT00000017088.1	ENSLACP00000016968.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/Cullin	1.70e-68	232.1	1008	1370

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/Cullin

   S: 66   LktynreWekfreqlkvlrkifayldrtyvkkskkvsevrkLaldlwrkeivedikkrllelllklieaeRkgeavdrrllsgvves 152
           L    ++W+ f+eql++ + +f      y+ k           +++w +ei+ed + +ll+l  kl+ a+R+++++++r+l++++++
   Q: 1008 LGPKPTFWPVFKEQLCRRTYLF------YTTK-----------VHTWCQEILED-RLQLLQLFNKLNSALRHEQMFADRFLPDAEAA 1076
           5556689***************......****...........9**********.******************************** PP
   S: 153  lveLslnklaiykesFEakfleatqefykaesaeflqe.nevdeYlkkvearlneeeeraaryleestetkLlevvekeliakhles 238
                   +a++++++Ea+  + +q +++++ a+ +   + ++eYl++ e + + ++++a + ++++++t+Ll++v+   ++   e+
   Q: 1077 --------EALGRTCWEALINPIVQSVTATDTASPSPMsWLLTEYLENSEISRRSKSRAAIFNSRVRRLTHLLVHVDTSRVE--TEE 1153
           ........9***************************999*******************************************..566 PP
   S: 239  llaelvallrdkktedlsrmykLlsrvlngleellkeleshikeqgkaaltaeekekdpkkyVerllelknklqklvseaFnndakF 325
           l ++  +   +k++e +s   k  ++ + ++  +++++++++++q+k++l++++++ +   +Ve + +l+ +l+k+++e+F+++++F
   Q: 1154 LKPP-TKPEGNKRKEPVSTAAKAKEKTTSSVTGITQCWQEVVQQQVKKFLESSWNSPS---FVEYYRNLYLRLKKAMEELFGQQTAF 1236
           5544.556778899999999999999999*****************************...************************** PP
   S: 326  lkaldkafetfvnknsvlkaakspEllAryiDqlLrksskglteeeleaqldkvllvfkyisekdv...FekyYkkhLakRLlsgks 409
           + al+++f++++++ s+l+a +++E++AryiDq++++s   + +   ++ql+++l+ + ++s++++   Fe++Y+ +L +RLl+   
   Q: 1237 MLALRQGFSAALLQLSFLTAMHVSEQFARYIDQRIQESGMDTSNVGRLNQLQQFLEPILFLSGLELantFEHFYRFYLGDRLLT--Q 1321
           **************************************88899999**************************************..9 PP
   S: 410  asseaEesviekLkeecgaeftskL.erMfqdlkvSedlnrqFk........e 453
              ++E +vie++    g +f+++  ++M+++l+ S++l+++F+        +
   Q: 1322 GNAWLESAVIEQV----GTCFPNRFpQQMVKNLSESKELQEEFHlyrlqqldK 1370
           99***********....***************************666633322 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

GGGVTMVGER RNGNLLVQLG PKMQAYPEEL IRQRRAQDGH MEYLIRWNVL AVEETGTGSS 60
GSASSSADSK AENILMWMSA EDVYANCPTL LGKRKPEAQR VPEEQATPSG FSADVTLDEM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGTGGTGGAG TCACCATGGT GGGAGAGAGA AGAAACGGGA ACCTGCTGGT CCAATTGGGC 60
CCCAAAATGC AGGCATACCC CGAGGAGCTG ATTCGTCAGC GCCGCGCCCA GGATGGTCAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR004939--APC_su10/DOC_dom
IPR016024--ARM-type_fold
IPR011987--ATPase_V1-cplx_hsu_C
IPR021097--CPH_domain
IPR016158--Cullin_homology
IPR008979--Galactose-bd-like
IPR014722--Rib_L2_dom2

PROSITE

PS50069--CULLIN_2
PS51284--DOC

Pfam

PF03256--ANAPC10
PF11515--Cul7

SMART

SM01337--APC10

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002360	Ailuropoda melanoleuca	43.82	0.00e+00	1005.00
IUUC-Apl-003458	Anas platyrhynchos	64.14	6.00e-88	320.00
IUUC-Aca-004815	Anolis carolinensis	67.25	0.00e+00	950.00
IUUC-Ame-010611	Astyanax mexicanus	73.44	0.00e+00	1102.00
IUUC-Bta-013285	Bos taurus	54.47	0.00e+00	738.00
IUUC-Cja-019033	Callithrix jacchus	42.58	0.00e+00	989.00
IUUC-Cfa-020119	Canis familiaris	57.47	0.00e+00	801.00
IUUC-Cpo-022473	Cavia porcellus	60.06	0.00e+00	752.00
IUUC-Csa-023798	Chlorocebus sabaeus	44.02	0.00e+00	1016.00
IUUC-Cho-024879	Choloepus hoffmanni	55.07	1.00e-47	186.00
IUUC-Cin-025402	Ciona intestinalis	34.17	3.00e-103	370.00
IUUC-Dno-028904	Dasypus novemcinctus	59.34	0.00e+00	796.00
IUUC-Dor-030234	Dipodomys ordii	42.47	0.00e+00	1015.00
IUUC-Ete-032516	Echinops telfairi	52.53	1.00e-143	505.00
IUUC-Eca-033408	Equus caballus	46.73	0.00e+00	771.00
IUUC-Eeu-035166	Erinaceus europaeus	59.72	2.00e-162	568.00
IUUC-Fca-035483	Felis catus	44.21	0.00e+00	1016.00
IUUC-Fal-036672	Ficedula albicollis	58.20	0.00e+00	823.00
IUUC-Gmo-038795	Gadus morhua	55.32	0.00e+00	952.00
IUUC-Gga-040154	Gallus gallus	54.01	4.00e-62	234.00
IUUC-Gac-041628	Gasterosteus aculeatus	73.59	0.00e+00	1047.00
IUUC-Ggo-044721	Gorilla gorilla	54.65	0.00e+00	711.00
IUUC-Hsa-046406	Homo sapiens	44.25	0.00e+00	1017.00
IUUC-Itr-048525	Ictidomys tridecemlineatus	55.09	0.00e+00	718.00
IUUC-Loc-052706	Lepisosteus oculatus	76.45	0.00e+00	1154.00
IUUC-Laf-054068	Loxodonta africana	43.68	0.00e+00	1007.00
IUUC-Mcc-055464	Macaca mulatta	44.16	0.00e+00	1020.00
IUUC-Meu-056198	Macropus eugenii	44.53	0.00e+00	720.00
IUUC-Mga-059683	Meleagris gallopavo	60.77	2.00e-36	146.00
IUUC-Mmr-061464	Microcebus murinus	44.15	0.00e+00	1026.00
IUUC-Mdo-062018	Monodelphis domestica	49.15	0.00e+00	823.00
IUUC-Mmu-063413	Mus musculus	52.84	0.00e+00	680.00
IUUC-Mpu-066146	Mustela putorius furo	55.79	0.00e+00	725.00
IUUC-Mlu-067473	Myotis lucifugus	56.05	0.00e+00	752.00
IUUC-Nle-069292	Nomascus leucogenys	56.58	0.00e+00	747.00
IUUC-Opr-070670	Ochotona princeps	41.04	0.00e+00	920.00
IUUC-Ont-071953	Oreochromis niloticus	72.30	0.00e+00	1097.00
IUUC-Oan-073451	Ornithorhynchus anatinus	54.92	0.00e+00	671.00
IUUC-Ocu-074155	Oryctolagus cuniculus	42.35	0.00e+00	960.00
IUUC-Ola-087072	Oryzias latipes	70.63	0.00e+00	1095.00
IUUC-Oga-089084	Otolemur garnettii	47.47	0.00e+00	832.00
IUUC-Oar-090029	Ovis aries	47.05	0.00e+00	827.00
IUUC-Ptr-091282	Pan troglodytes	44.60	0.00e+00	1041.00
IUUC-Pan-091883	Papio anubis	44.02	0.00e+00	1023.00
IUUC-Pma-094192	Petromyzon marinus	52.74	0.00e+00	792.00
IUUC-Pfo-096773	Poecilia formosa	55.71	2.00e-94	342.00
IUUC-Pab-098383	Pongo abelii	43.46	0.00e+00	998.00
IUUC-Pca-100519	Procavia capensis	50.00	4.00e-106	380.00
IUUC-Pva-102417	Pteropus vampyrus	47.20	0.00e+00	832.00
IUUC-Rno-105962	Rattus norvegicus	45.71	0.00e+00	783.00
IUUC-Sha-106896	Sarcophilus harrisii	60.61	1.00e-135	478.00
IUUC-Sar-113132	Sorex araneus	56.00	9.00e-137	482.00
IUUC-Ssc-115899	Sus scrofa	53.59	0.00e+00	686.00
IUUC-Tgu-116915	Taeniopygia guttata	56.21	1.00e-137	483.00
IUUC-Tru-118013	Takifugu rubripes	68.27	0.00e+00	1009.00
IUUC-Tsy-118860	Tarsius syrichta	50.15	0.00e+00	628.00
IUUC-Tni-120062	Tetraodon nigroviridis	71.84	0.00e+00	1049.00
IUUC-Tbe-127660	Tupaia belangeri	43.69	4.00e-117	416.00
IUUC-Ttr-128780	Tursiops truncatus	56.22	0.00e+00	754.00
IUUC-Vpa-130086	Vicugna pacos	51.29	3.00e-117	416.00
IUUC-Xtr-132882	Xenopus tropicalis	62.98	0.00e+00	875.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence