iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ont-071851

Ensembl Protein ID

ENSONIP00000024349.1

UniProt Accession

I3KTA3; I3KTA3_ORENI

Genbank Protein ID

ENSONIP00000024349

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AERX01006847

Gene Name

kif21b

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000019345.1	ENSONIT00000024370.1	ENSONIP00000024349.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.80e-29	99.1	1588	1622
UBD/Beta-Prp	1.10e-42	146.7	1346	1586

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgv 34
           H+d+v++la+ ++ ++l+sG++ g +kvW+++ ++
   Q: 1588 HKDWVCALAYvPGrPMLLSGCRGGMLKVWNVDNFT 1622
           ***********999****************98765 PP

UBD/Beta-Prp

   S: 46   rslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletg.qclee 131
           +  +gh+++v +v+  ++  +l tgs+Drt k w+l tg+ ++tlkgh ++v+s++++p ++ lv   + ++i+vwd++   +c+++
   Q: 1346 SVAEGHSKPVLCVDATDE--LLFTGSKDRTCKMWNLVTGQEIVTLKGHPNNVVSVKYCP-SSCLVFSVSTSYIKVWDIRDAaKCVRT 1429
           5569***********999..9**************************************.67777777799*******986266666 PP
   S: 132  .....................tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsng...ke 194
                                t+++ +  +n ++++p+g++l ++ + +tvr+Wdl++++ + +ltg h +sv +l++ ++     +
   Q: 1430 ltssgqvvsgdacagtttrtiTFAQGECQINQIALNPSGSVLYAA-AGNTVRIWDLNRMQAMGKLTG-HIGSVMCLTVGQSLlgkDQ 1514
           *********************99999***********98544443.4579****************9.*********8887788899 PP
   S: 195  lvsgsldgtvklwdlqtgecvrtlnght......dnvksvrfspnderlvsgssDgsiriWdlrsgdllktlql 262
           +++gs+d +vk++d+ +g+  +   +h+      d + ++++   ++ l sgs D+ i+ W l++++l++++ +
   Q: 1515 VITGSKDHYVKVFDVAEGTLGNVGPAHNfepphyDGIECLAVQ--GDVLFSGSRDNGIKKWELEQQELTQQIPN 1586
           *******************988888888888888*********..***********************998765 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MGSQGDCCVK VALRIRPQMA KEKIEGCHVC TLVTPGEPQV LLGKDKAFTY DFVFDIDSEQ 60
PHIYQTCVYK LIEGCFEGYN ATVFAYGQTG SGKTYTMGTG FDVSLSPQDQ GIIPRAVHQL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGTGCTCGC TCAGAGAAGC GGTGTGGCTG CAGAGAGACG CTCGTACGCT TCCCTCACAG 60
GCACTTTGAA CAGGATGTAG CGACTGAGCT AGACCACGGA AAGAAAAAAG CGAAAGAAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0472--Membrane
KW-0505--Motor protein
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0853--WD repeat

Interpro

IPR019821--Kinesin_motor_CS
IPR001752--Kinesin_motor_dom
IPR027417--P-loop_NTPase
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00411--KINESIN_MOTOR_1
PS50067--KINESIN_MOTOR_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00225--Kinesin
PF00400--WD40

PRINTS

PR00380--KINESINHEAVY

SMART

SM00129--KISc
SM00320--WD40

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0005524--F:ATP binding
GO:0003777--F:microtubule motor activity
GO:0007018--P:microtubule-based movement

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001279	Ailuropoda melanoleuca	72.31	0.00e+00	2166.00
IUUC-Apl-003204	Anas platyrhynchos	73.15	0.00e+00	725.00
IUUC-Aca-004506	Anolis carolinensis	72.49	0.00e+00	1398.00
IUUC-Ame-011515	Astyanax mexicanus	79.58	0.00e+00	2499.00
IUUC-Bta-013185	Bos taurus	64.11	0.00e+00	1119.00
IUUC-Cja-018844	Callithrix jacchus	71.20	0.00e+00	2167.00
IUUC-Cfa-021187	Canis familiaris	73.04	0.00e+00	2250.00
IUUC-Cpo-022444	Cavia porcellus	72.58	0.00e+00	2183.00
IUUC-Csa-023852	Chlorocebus sabaeus	73.18	0.00e+00	2244.00
IUUC-Csv-026158	Ciona savignyi	53.01	8.00e-175	608.00
IUUC-Dre-027839	Danio rerio	78.02	0.00e+00	2459.00
IUUC-Dno-030058	Dasypus novemcinctus	72.25	0.00e+00	2146.00
IUUC-Dor-030673	Dipodomys ordii	69.82	0.00e+00	2083.00
IUUC-Ete-032705	Echinops telfairi	64.91	0.00e+00	696.00
IUUC-Eca-033885	Equus caballus	72.49	0.00e+00	2169.00
IUUC-Eeu-035338	Erinaceus europaeus	61.78	0.00e+00	1674.00
IUUC-Fca-035388	Felis catus	72.81	0.00e+00	2065.00
IUUC-Fal-037044	Ficedula albicollis	73.80	0.00e+00	2254.00
IUUC-Gmo-039034	Gadus morhua	77.08	0.00e+00	2305.00
IUUC-Gac-041328	Gasterosteus aculeatus	88.56	0.00e+00	2815.00
IUUC-Ggo-045392	Gorilla gorilla	72.71	0.00e+00	2225.00
IUUC-Hsa-046713	Homo sapiens	73.12	0.00e+00	2242.00
IUUC-Itr-049068	Ictidomys tridecemlineatus	74.49	0.00e+00	1295.00
IUUC-Lch-049786	Latimeria chalumnae	73.58	0.00e+00	2293.00
IUUC-Loc-052703	Lepisosteus oculatus	81.27	0.00e+00	2586.00
IUUC-Laf-054193	Loxodonta africana	68.16	0.00e+00	1268.00
IUUC-Mcc-055484	Macaca mulatta	71.89	0.00e+00	2211.00
IUUC-Meu-056278	Macropus eugenii	69.44	0.00e+00	994.00
IUUC-Mga-059816	Meleagris gallopavo	70.85	0.00e+00	2157.00
IUUC-Mmr-061071	Microcebus murinus	70.40	0.00e+00	2186.00
IUUC-Mdo-062845	Monodelphis domestica	73.35	0.00e+00	2281.00
IUUC-Mmu-063967	Mus musculus	72.54	0.00e+00	2212.00
IUUC-Mpu-066448	Mustela putorius furo	72.23	0.00e+00	2232.00
IUUC-Nle-070037	Nomascus leucogenys	75.10	0.00e+00	1432.00
IUUC-Opr-070325	Ochotona princeps	69.29	0.00e+00	2047.00
IUUC-Oan-073615	Ornithorhynchus anatinus	73.19	0.00e+00	2056.00
IUUC-Ocu-073855	Oryctolagus cuniculus	73.09	0.00e+00	2230.00
IUUC-Ola-086703	Oryzias latipes	90.20	0.00e+00	2868.00
IUUC-Oga-088171	Otolemur garnettii	71.38	0.00e+00	2134.00
IUUC-Ptr-090535	Pan troglodytes	74.31	0.00e+00	1410.00
IUUC-Pan-091917	Papio anubis	71.97	0.00e+00	2038.00
IUUC-Psi-093752	Pelodiscus sinensis	68.48	0.00e+00	1209.00
IUUC-Pfo-096827	Poecilia formosa	84.86	0.00e+00	2677.00
IUUC-Pab-098441	Pongo abelii	73.18	0.00e+00	2243.00
IUUC-Pca-100781	Procavia capensis	77.95	0.00e+00	738.00
IUUC-Pva-103099	Pteropus vampyrus	70.64	0.00e+00	1040.00
IUUC-Rno-105872	Rattus norvegicus	72.36	0.00e+00	2235.00
IUUC-Sha-107097	Sarcophilus harrisii	73.30	0.00e+00	2150.00
IUUC-Ssc-115638	Sus scrofa	71.42	0.00e+00	1914.00
IUUC-Tgu-116504	Taeniopygia guttata	75.87	0.00e+00	811.00
IUUC-Tru-118242	Takifugu rubripes	88.80	0.00e+00	2900.00
IUUC-Tni-119976	Tetraodon nigroviridis	91.87	0.00e+00	1153.00
IUUC-Ttr-128824	Tursiops truncatus	70.97	0.00e+00	1764.00
IUUC-Xtr-131798	Xenopus tropicalis	60.11	0.00e+00	1802.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence