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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Dme-031945
Ensembl Protein ID FBpp0072694
UniProt Accession Q9W0B8; Q9W0B8_DROME
Genbank Protein ID AAF47534.1; AAF47535.1; AAL68241.1
Protein Name Coatomer subunit alpha
Genbank Nucleotide ID AE014296; AE014296; AY075425
Gene Name alphaCOP; alpha-COP; alpha-Cop; alphaCop; DmelCG7961; CG7961; Dmel_CG7961
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
FBgn0025725 FBtr0072812 FBpp0072694
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpress
DNA & RNA Element
microRNARAID2
Protein-protein Interaction
IIDiRefIndexPINAMentha
Post-translational Modifications (PTMs)
CPLMdbPAF
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 1.10e-37 126.4 50 86
UBD/Beta-Prp 2.80e-75 253.3 3 327
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           H ++v+++af +  +l+vsG+dD +ikvW++++ +++
   Q: 50   HDGPVRGVAFhQQmPLFVSGGDDYKIKVWNYKQRRCI 86
           99********95559***************9988875 PP
   

   UBD/Beta-Prp
   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlsls 101
           t +++++++++ + f+p++++++++  +g i++wd+++ +ll+++ +h+++v+ v f+++ +++v+g++D+ ikvw+++++ c+ tl +h d+v++++
   Q: 3    TNFESKSARVKGLSFHPKRPWILVSLHSGVIQLWDYRMHTLLEKFDEHDGPVRGVAFHQQMPLFVSGGDDYKIKVWNYKQRRCIFTLLAHLDYVRTVA 100
           557889999***************************************************************************************** PP
   S: 102  fspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl..............................ktg 169
           f+ +  +++s+s+d+tir+w+++++ c+  +l+gh++ v+c+++hp+++ +vs+slD+tvr+Wd+                              + +
   Q: 101  FHHEYPWILSASDDQTIRIWNWQSRNCIC-VLTGHNHYVMCAQFHPTEDQIVSASLDQTVRVWDIsglrkknvapgpgglddhlkghpgatdlfgQAD 197
           *****************************.*****************************************************************666 PP
   S: 170  kllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgec..vrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhns 265
            ++++  +gh++ v++ sf+++ + +vsg++d+ vklw + + +   v+t++gh +nv+sv f+p++++++s ++D+sir+Wd++++++l t+ + n+
   Q: 198  AVVKHVLEGHDRGVNWASFHPTLPLIVSGADDRLVKLWRMNEYKAweVDTCRGHYNNVSSVLFHPRQDLILSNGEDRSIRVWDMTKRQCLFTFRRDNE 295
           666666556********************************766667*************************************************** PP
   S: 266  svisvavlsfgdnvlvlgsedskvniwklkknep 299
           +++  ++ +++ n +++g  d+   ++kl++++p
   Q: 296  RFWILTA-HPTLNLFAAG-HDGGMVVFKLERERP 327
           *******.7777666655.58999999*998775 PP
   
Organism Drosophila melanogaster
Functional Description
(View)

Functional Description


     The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.
 The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.
Protein Sequence
(Fasta)
MLTNFESKSA RVKGLSFHPK RPWILVSLHS GVIQLWDYRM HTLLEKFDEH DGPVRGVAFH 60
QQMPLFVSGG DDYKIKVWNY KQRRCIFTLL AHLDYVRTVA FHHEYPWILS ASDDQTIRIW 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Dme-031945|E3,WD_repeat;UBD,Beta-Prp|Drosophila melanogaster
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATAATTGACG TGTCACAATT TCGACGATTG GTTGGTGTTT TTCATAAAAT TAATTGTTGG 60
CAGTATATTA CGTGTTACTT GTAGCGTATC AATAAAATGG GTTTGTTCTA ACACCCACCT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Dme-031945|E3,WD_repeat;UBD,Beta-Prp|Drosophila melanogaster
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0167--Capsid protein
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0813--Transport
KW-0946--Virion
KW-0853--WD repeat
Interpro

IPR016391--Coatomer_asu
IPR010714--Coatomer_asu_C
IPR006692--Coatomer_WD-assoc_reg
IPR020472--G-protein_beta_WD-40_rep
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF04053--Coatomer_WDAD
PF06957--COPI_C
PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM00320--WD40
Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0000139--C:Golgi membrane
GO:0019028--C:viral capsid
GO:0005198--F:structural molecule activity
GO:0000902--P:cell morphogenesis
GO:0006888--P:ER to Golgi vesicle-mediated transport
GO:0006891--P:intra-Golgi vesicle-mediated transport
GO:0006886--P:intracellular protein transport
GO:0007112--P:male meiosis cytokinesis
GO:0048812--P:neuron projection morphogenesis
GO:0006909--P:phagocytosis
GO:0010883--P:regulation of lipid storage
GO:0006890--P:retrograde vesicle-mediated transport, Golgi to ER
GO:0016192--P:vesicle-mediated transport
KEGG dme:Dmel_CG7961
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000201 Aegilops tauschii 51.28 0.00e+00 1220.00
IUUC-Aml-001758 Ailuropoda melanoleuca 69.21 0.00e+00 1769.00
IUUC-Atr-002493 Amborella trichopoda 62.33 0.00e+00 1067.00
IUUC-Apl-003385 Anas platyrhynchos 65.62 0.00e+00 1449.00
IUUC-Aca-005154 Anolis carolinensis 78.10 4.00e-100 356.00
IUUC-Aly-006020 Arabidopsis lyrata 60.58 0.00e+00 1060.00
IUUC-Ath-007360 Arabidopsis thaliana 60.82 0.00e+00 1060.00
IUUC-Ago-007992 Ashbya gossypii 41.95 0.00e+00 967.00
IUUC-Acl-008027 Aspergillus clavatus 56.39 0.00e+00 986.00
IUUC-Afl-008644 Aspergillus flavus 56.24 0.00e+00 989.00
IUUC-Afu-008964 Aspergillus fumigatus 56.44 0.00e+00 998.00
IUUC-Ani-009379 Aspergillus nidulans 55.88 0.00e+00 987.00
IUUC-Ang-009756 Aspergillus niger 57.23 0.00e+00 1004.00
IUUC-Aor-010174 Aspergillus oryzae 56.24 0.00e+00 989.00
IUUC-Ate-010302 Aspergillus terreus 48.03 0.00e+00 1187.00
IUUC-Ame-011229 Astyanax mexicanus 75.15 0.00e+00 1323.00
IUUC-Bgr-012300 Blumeria graminis 46.44 0.00e+00 1092.00
IUUC-Bta-012524 Bos taurus 69.79 0.00e+00 1759.00
IUUC-Bci-013781 Botrytis cinerea 55.53 0.00e+00 981.00
IUUC-Bdi-014549 Brachypodium distachyon 59.74 0.00e+00 1054.00
IUUC-Bol-015925 Brassica oleracea 60.17 0.00e+00 1051.00
IUUC-Bra-016978 Brassica rapa 59.81 0.00e+00 1044.00
IUUC-Cel-018115 Caenorhabditis elegans 62.28 0.00e+00 1100.00
IUUC-Cja-019107 Callithrix jacchus 67.30 0.00e+00 1726.00
IUUC-Cfa-020675 Canis familiaris 69.11 0.00e+00 1739.00
IUUC-Cpo-021813 Cavia porcellus 76.17 0.00e+00 1366.00
IUUC-Cre-022969 Chlamydomonas reinhardtii 62.19 0.00e+00 1065.00
IUUC-Csa-023523 Chlorocebus sabaeus 69.79 0.00e+00 1782.00
IUUC-Cho-024704 Choloepus hoffmanni 74.27 1.00e-142 500.00
IUUC-Cin-025572 Ciona intestinalis 69.48 0.00e+00 1248.00
IUUC-Csv-025864 Ciona savignyi 69.99 0.00e+00 1190.00
IUUC-Cgl-026510 Colletotrichum gloeosporioides 56.66 0.00e+00 1001.00
IUUC-Cne-027053 Cryptococcus neoformans 56.73 0.00e+00 1004.00
IUUC-Cme-027222 Cyanidioschyzon merolae 39.32 1.00e-136 481.00
IUUC-Dre-027421 Danio rerio 67.65 0.00e+00 1714.00
IUUC-Dno-029303 Dasypus novemcinctus 69.40 0.00e+00 1770.00
IUUC-Dor-030290 Dipodomys ordii 60.42 0.00e+00 674.00
IUUC-Dse-031543 Dothistroma septosporum 45.40 0.00e+00 1093.00
IUUC-Ete-032873 Echinops telfairi 73.12 0.00e+00 1295.00
IUUC-Eca-033773 Equus caballus 76.17 0.00e+00 1366.00
IUUC-Eeu-034874 Erinaceus europaeus 62.88 2.00e-121 429.00
IUUC-Fca-035739 Felis catus 76.00 0.00e+00 1347.00
IUUC-Fal-037263 Ficedula albicollis 70.42 0.00e+00 1192.00
IUUC-Fox-037738 Fusarium oxysporum 47.60 0.00e+00 1183.00
IUUC-Fso-038153 Fusarium solani 48.12 0.00e+00 1173.00
IUUC-Gmo-039602 Gadus morhua 74.22 0.00e+00 1300.00
IUUC-Ggr-039931 Gaeumannomyces graminis 55.81 0.00e+00 997.00
IUUC-Gga-040590 Gallus gallus 75.69 0.00e+00 1362.00
IUUC-Gac-041318 Gasterosteus aculeatus 67.46 0.00e+00 1731.00
IUUC-Gma-043894 Glycine max 61.25 0.00e+00 1065.00
IUUC-Ggo-045029 Gorilla gorilla 69.37 0.00e+00 1775.00
IUUC-Hsa-046078 Homo sapiens 69.37 0.00e+00 1775.00
IUUC-Hvu-047556 Hordeum vulgare 52.21 0.00e+00 1287.00
IUUC-Itr-048881 Ictidomys tridecemlineatus 64.07 0.00e+00 1130.00
IUUC-Kpa-049256 Komagataella pastoris 52.27 0.00e+00 889.00
IUUC-Lch-049706 Latimeria chalumnae 68.58 0.00e+00 1741.00
IUUC-Lpe-051316 Leersia perrieri 60.94 0.00e+00 1065.00
IUUC-Loc-051867 Lepisosteus oculatus 59.13 0.00e+00 981.00
IUUC-Lma-053138 Leptosphaeria maculans 55.36 0.00e+00 998.00
IUUC-Laf-053510 Loxodonta africana 69.39 0.00e+00 1776.00
IUUC-Mcc-055836 Macaca mulatta 75.36 0.00e+00 1356.00
IUUC-Meu-056238 Macropus eugenii 68.06 0.00e+00 945.00
IUUC-Mor-057172 Magnaporthe oryzae 47.52 0.00e+00 1163.00
IUUC-Mtr-058248 Medicago truncatula 61.01 0.00e+00 1060.00
IUUC-Mla-059019 Melampsora laricipopulina 56.97 0.00e+00 1035.00
IUUC-Mga-059499 Meleagris gallopavo 75.51 0.00e+00 1355.00
IUUC-Mvi-060336 Microbotryum violaceum 56.60 0.00e+00 1030.00
IUUC-Mmr-061102 Microcebus murinus 76.11 0.00e+00 1352.00
IUUC-Mdo-062594 Monodelphis domestica 68.81 0.00e+00 1774.00
IUUC-Mmu-063736 Mus musculus 75.24 0.00e+00 1356.00
IUUC-Mac-065272 Musa acuminata 57.35 0.00e+00 965.00
IUUC-Mpu-066701 Mustela putorius furo 75.69 0.00e+00 1362.00
IUUC-Mlu-067392 Myotis lucifugus 62.88 5.00e-123 435.00
IUUC-Nfi-068270 Neosartorya fischeri 56.75 0.00e+00 994.00
IUUC-Ncr-068892 Neurospora crassa 56.41 0.00e+00 994.00
IUUC-Nle-069634 Nomascus leucogenys 76.92 0.00e+00 1098.00
IUUC-Opr-070952 Ochotona princeps 58.56 0.00e+00 981.00
IUUC-Ont-072488 Oreochromis niloticus 75.57 0.00e+00 1323.00
IUUC-Ocu-074211 Oryctolagus cuniculus 69.55 0.00e+00 1773.00
IUUC-Oba-075761 Oryza barthii 60.70 0.00e+00 1062.00
IUUC-Obr-076429 Oryza brachyantha 60.82 0.00e+00 1064.00
IUUC-Ogl-077364 Oryza glaberrima 60.70 0.00e+00 1063.00
IUUC-Ogu-078257 Oryza glumaepatula 60.89 0.00e+00 1062.00
IUUC-Oin-080029 Oryza indica 60.82 0.00e+00 1063.00
IUUC-Olo-080895 Oryza longistaminata 60.82 0.00e+00 1054.00
IUUC-Ome-081993 Oryza meridionalis 62.42 0.00e+00 991.00
IUUC-Oni-082608 Oryza nivara 61.06 0.00e+00 1063.00
IUUC-Opu-083370 Oryza punctata 61.18 0.00e+00 1067.00
IUUC-Oru-084274 Oryza rufipogon 60.70 0.00e+00 1063.00
IUUC-Osa-085841 Oryza sativa 61.06 0.00e+00 1065.00
IUUC-Ola-086921 Oryzias latipes 75.48 0.00e+00 1315.00
IUUC-Olu-087639 Ostreococcus lucimarinus 53.66 0.00e+00 1310.00
IUUC-Oga-087991 Otolemur garnettii 66.11 0.00e+00 1670.00
IUUC-Oar-089590 Ovis aries 69.71 0.00e+00 1776.00
IUUC-Ptr-090808 Pan troglodytes 69.37 0.00e+00 1775.00
IUUC-Pan-092475 Papio anubis 69.33 0.00e+00 1768.00
IUUC-Psi-093044 Pelodiscus sinensis 65.25 0.00e+00 1093.00
IUUC-Pno-094839 Phaeosphaeria nodorum 54.21 0.00e+00 928.00
IUUC-Ppa-095254 Physcomitrella patens 64.58 0.00e+00 1115.00
IUUC-Pfo-097493 Poecilia formosa 68.34 0.00e+00 1727.00
IUUC-Pab-098497 Pongo abelii 69.79 0.00e+00 1782.00
IUUC-Pop-099992 Populus trichocarpa 60.89 0.00e+00 1063.00
IUUC-Pca-100413 Procavia capensis 66.61 0.00e+00 769.00
IUUC-Ppe-101899 Prunus persica 62.21 0.00e+00 1087.00
IUUC-Pva-102126 Pteropus vampyrus 66.96 0.00e+00 1689.00
IUUC-Pgr-103376 Puccinia graminis 57.46 0.00e+00 1026.00
IUUC-Ptt-103978 Puccinia triticina 48.40 0.00e+00 802.00
IUUC-Pte-104126 Pyrenophora teres 54.65 0.00e+00 949.00
IUUC-Pyt-104778 Pyrenophora triticirepentis 45.21 6.00e-174 603.00
IUUC-Rno-105428 Rattus norvegicus 76.17 0.00e+00 1365.00
IUUC-Sce-106464 Saccharomyces cerevisiae 49.34 0.00e+00 849.00
IUUC-Sha-107301 Sarcophilus harrisii 68.72 0.00e+00 1746.00
IUUC-Sja-107961 Schizosaccharomyces japonicus 44.77 0.00e+00 1047.00
IUUC-Spo-108217 Schizosaccharomyces pombe 46.01 0.00e+00 1082.00
IUUC-Ssl-108643 Sclerotinia sclerotiorum 55.53 0.00e+00 980.00
IUUC-Smo-109582 Selaginella moellendorffii 62.95 0.00e+00 1097.00
IUUC-Sit-109697 Setaria italica 60.70 0.00e+00 1062.00
IUUC-Sly-111447 Solanum lycopersicum 62.58 0.00e+00 1097.00
IUUC-Stu-112564 Solanum tuberosum 62.94 0.00e+00 1093.00
IUUC-Sar-113313 Sorex araneus 58.83 0.00e+00 973.00
IUUC-Sbi-114388 Sorghum bicolor 60.94 0.00e+00 1065.00
IUUC-Sre-115209 Sporisorium reilianum 55.01 0.00e+00 992.00
IUUC-Ssc-115933 Sus scrofa 69.55 0.00e+00 1772.00
IUUC-Tgu-117109 Taeniopygia guttata 63.45 6.00e-144 503.00
IUUC-Tru-117772 Takifugu rubripes 61.04 1.00e-119 424.00
IUUC-Tsy-119105 Tarsius syrichta 69.19 0.00e+00 1217.00
IUUC-Tni-120556 Tetraodon nigroviridis 54.22 0.00e+00 748.00
IUUC-Tca-121545 Theobroma cacao 62.82 0.00e+00 1087.00
IUUC-Tre-121951 Trichoderma reesei 56.49 0.00e+00 997.00
IUUC-Tvi-122359 Trichoderma virens 56.65 0.00e+00 1003.00
IUUC-Tae-123688 Triticum aestivum 52.13 0.00e+00 1285.00
IUUC-Tur-126016 Triticum urartu 50.34 0.00e+00 1154.00
IUUC-Tme-127170 Tuber melanosporum 48.63 0.00e+00 1182.00
IUUC-Tbe-127882 Tupaia belangeri 54.75 6.00e-173 600.00
IUUC-Ttr-128217 Tursiops truncatus 67.28 0.00e+00 1698.00
IUUC-Uma-129337 Ustilago maydis 55.01 0.00e+00 989.00
IUUC-Vda-129828 Verticillium dahliae 55.19 0.00e+00 977.00
IUUC-Vpa-130537 Vicugna pacos 68.55 0.00e+00 1756.00
IUUC-Vvi-130958 Vitis vinifera 61.85 0.00e+00 1076.00
IUUC-Xtr-132857 Xenopus tropicalis 66.37 0.00e+00 1641.00
IUUC-Xma-133138 Xiphophorus maculatus 68.42 0.00e+00 1730.00
IUUC-Yli-134399 Yarrowia lipolytica 49.13 0.00e+00 841.00
IUUC-Zma-135612 Zea mays 58.64 0.00e+00 1039.00
Created Date 25-Jun-2017

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