iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-010816

Ensembl Protein ID

ENSAMXP00000005649.1

UniProt Accession

W5KDI8; W5KDI8_ASTMX

Genbank Protein ID

ENSAMXP00000005649

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

APWO01100375

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000005512.1	ENSAMXT00000005649.1	ENSAMXP00000005649.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.70e-36	126.6	720	881

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/HECT

   S: 3    sdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlp 91
            dlkk l+v f gEe++d+gGvt+ef+ ll+kel +p +g+f++ ++++  ++ ++        + ++F+++G+++g+a++++ ++dl+
   Q: 720  VDLKKPLKVIFDGEEAVDAGGVTKEFFLLLLKELLDPVYGMFTHYSESNLLWFSDKCFV-----EHNWFNLIGIVCGLAIYNSTVVDLH 803
           589*******************************************9999999888665.....568********************** PP
   S: 92   lsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNk 170
           ++ ++yk+ll+++ sl+dl+e+ p+  +sl+++++++ +diee+ ++l+f ++ e++g t+++eL+pgGeni V  +N+
   Q: 804  FPLVLYKKLLDVSPSLDDLKELSPTEGRSLQQLLDYEGDDIEET-FCLNFAITREHYGMTEVKELVPGGENITVDRSNR 881
           ************************************99999997.********************************98 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

MLCWGSSAWG QLGLGDAEPV VAEPRSCRMF SGRGLKEVAC RGQHSLFLLH DGSVYSCGSN 60
SHGQLGHEKP GNKPELVVAL DAQKIAGVAC GDAHSLAVNE QGQVFAWGTG EKGQLGLGTV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTTGCCATT CACTCCAAGG GGAGAAGGCA GGGCTGCTCA GCCTAGGGCA CTCCCACCCT 60
CCATCTCCCT CTCTTGTATC CTTCCATTTC CCTCTCTCCA TCTTGGTCTC TTTCTCTCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR009091--RCC1/BLIP-II
IPR000408--Reg_chr_condens

PROSITE

PS50237--HECT
PS00626--RCC1_2
PS50012--RCC1_3

Pfam

PF00632--HECT
PF00415--RCC1

PRINTS

PR00633--RCCNDNSATION

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001673	Ailuropoda melanoleuca	65.92	0.00e+00	1184.00
IUUC-Apl-003535	Anas platyrhynchos	67.15	0.00e+00	1188.00
IUUC-Aca-005223	Anolis carolinensis	66.14	0.00e+00	1188.00
IUUC-Bta-013373	Bos taurus	66.14	0.00e+00	1186.00
IUUC-Bdi-014791	Brachypodium distachyon	37.00	1.00e-50	193.00
IUUC-Cja-019609	Callithrix jacchus	65.96	0.00e+00	1180.00
IUUC-Cfa-021071	Canis familiaris	66.03	0.00e+00	1183.00
IUUC-Cpo-021548	Cavia porcellus	65.92	0.00e+00	1179.00
IUUC-Cre-023014	Chlamydomonas reinhardtii	37.79	7.00e-47	181.00
IUUC-Csa-023987	Chlorocebus sabaeus	66.03	0.00e+00	1183.00
IUUC-Cho-024325	Choloepus hoffmanni	72.75	0.00e+00	675.00
IUUC-Dre-027472	Danio rerio	82.78	0.00e+00	1514.00
IUUC-Dno-029241	Dasypus novemcinctus	65.13	0.00e+00	1163.00
IUUC-Dor-030672	Dipodomys ordii	56.61	0.00e+00	667.00
IUUC-Ete-032642	Echinops telfairi	64.63	0.00e+00	1111.00
IUUC-Eca-033646	Equus caballus	65.80	0.00e+00	1176.00
IUUC-Fal-036952	Ficedula albicollis	67.04	0.00e+00	1186.00
IUUC-Gmo-039297	Gadus morhua	77.84	0.00e+00	1342.00
IUUC-Gga-040591	Gallus gallus	65.60	0.00e+00	1176.00
IUUC-Gac-041741	Gasterosteus aculeatus	78.09	0.00e+00	1399.00
IUUC-Ggo-044769	Gorilla gorilla	65.84	0.00e+00	1177.00
IUUC-Hsa-046066	Homo sapiens	65.92	0.00e+00	1181.00
IUUC-Itr-048311	Ictidomys tridecemlineatus	65.27	0.00e+00	1183.00
IUUC-Lch-050301	Latimeria chalumnae	68.69	0.00e+00	1231.00
IUUC-Loc-052803	Lepisosteus oculatus	79.39	0.00e+00	1456.00
IUUC-Laf-053364	Loxodonta africana	66.03	0.00e+00	1184.00
IUUC-Mcc-054930	Macaca mulatta	65.92	0.00e+00	1183.00
IUUC-Meu-056274	Macropus eugenii	54.31	7.00e-160	558.00
IUUC-Mga-059563	Meleagris gallopavo	66.00	0.00e+00	1188.00
IUUC-Mmr-060792	Microcebus murinus	65.13	0.00e+00	1150.00
IUUC-Mdo-062195	Monodelphis domestica	65.71	0.00e+00	1192.00
IUUC-Mmu-063855	Mus musculus	65.47	0.00e+00	1177.00
IUUC-Mpu-066308	Mustela putorius furo	66.14	0.00e+00	1185.00
IUUC-Mlu-066927	Myotis lucifugus	66.48	0.00e+00	1186.00
IUUC-Nle-070090	Nomascus leucogenys	65.92	0.00e+00	1183.00
IUUC-Opr-070891	Ochotona princeps	59.09	0.00e+00	981.00
IUUC-Ont-072201	Oreochromis niloticus	77.50	0.00e+00	1371.00
IUUC-Ocu-074770	Oryctolagus cuniculus	66.25	0.00e+00	1186.00
IUUC-Ola-086550	Oryzias latipes	76.73	0.00e+00	1379.00
IUUC-Oga-088831	Otolemur garnettii	65.58	0.00e+00	1173.00
IUUC-Oar-090449	Ovis aries	66.14	0.00e+00	1183.00
IUUC-Pan-092135	Papio anubis	66.07	0.00e+00	1184.00
IUUC-Psi-093832	Pelodiscus sinensis	65.17	0.00e+00	1160.00
IUUC-Pfo-097268	Poecilia formosa	77.69	0.00e+00	1391.00
IUUC-Pab-098249	Pongo abelii	66.03	0.00e+00	1184.00
IUUC-Pca-100855	Procavia capensis	60.93	0.00e+00	900.00
IUUC-Pva-102506	Pteropus vampyrus	62.19	0.00e+00	1075.00
IUUC-Rno-105242	Rattus norvegicus	65.47	0.00e+00	1177.00
IUUC-Sit-110415	Setaria italica	34.10	2.00e-51	196.00
IUUC-Sar-113612	Sorex araneus	74.87	3.00e-164	572.00
IUUC-Ssc-115473	Sus scrofa	66.14	0.00e+00	1185.00
IUUC-Tgu-116974	Taeniopygia guttata	67.04	0.00e+00	1182.00
IUUC-Tru-118077	Takifugu rubripes	76.28	0.00e+00	1344.00
IUUC-Tsy-119619	Tarsius syrichta	57.48	0.00e+00	1013.00
IUUC-Tni-120807	Tetraodon nigroviridis	75.95	0.00e+00	1342.00
IUUC-Tbe-127640	Tupaia belangeri	63.21	0.00e+00	1094.00
IUUC-Ttr-129172	Tursiops truncatus	65.69	0.00e+00	1177.00
IUUC-Xtr-132194	Xenopus tropicalis	57.05	0.00e+00	929.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence