iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Gac-041927

Ensembl Protein ID

ENSGACP00000021396.1

UniProt Accession

G3PUV9; G3PUV9_GASAC

Protein Name

Uncharacterized protein

Gene Name

ITSN2 (1 of many)

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGACG00000016215.1	ENSGACT00000021437.1	ENSGACP00000021396.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	6.70e-57	189.7	1076	1127

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           +v+++ydy+a+n deL++ kG  + v  ++++d++W+kg  e++g  GlfP n+v+
   Q: 1076 QVIAIYDYKAANGDELSFSKGQLINV--HDKNDQDWWKG--ETNGATGLFPTNYVK 1127
           689***********************..59*********..9*************8 PP

Organism

Gasterosteus aculeatus

Protein Sequence
(Fasta)

LPLPPAKMNG GPSIWAISPE ERVKHDKKFD TLSPSMGYVS GEQAKKFLLQ SGLPGSVLAE 60
IWTLADMNKD GKMDRLEFSI AMKLIKLKLQ GTPLPSALPV IMKQPPVPAP SLSNPTSLLT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTGCCTCTGC CACCTGCAAA GATGAATGGT AAGACCTCTG CAGTTTGTGT GTTTGCATCG 60
AGCACTGTGT GTGGTTCGGG GGCTCCAATC TGCTGCACCG CCATATTATT AGTTCTACTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0106--Calcium
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000219--DH-domain
IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR000261--EH_dom
IPR027029--Intersectin-2
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS50010--DH_2
PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS50031--EH
PS50002--SH3

Pfam

PF12763--EF-hand_4
PF00621--RhoGEF
PF00018--SH3_1
PF07653--SH3_2
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00054--EFh
SM00027--EH
SM00326--SH3

Gene Ontology

GO:0005509--F:calcium ion binding
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0006897--P:endocytosis
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cel-018490	Caenorhabditis elegans	32.95	2.00e-48	187.00
IUUC-Cja-019259	Callithrix jacchus	48.07	8.00e-165	574.00
IUUC-Dme-032099	Drosophila melanogaster	33.94	5.00e-52	199.00
IUUC-Gmo-039079	Gadus morhua	65.50	0.00e+00	773.00
IUUC-Itr-048978	Ictidomys tridecemlineatus	50.30	1.00e-151	530.00
IUUC-Laf-053798	Loxodonta africana	50.69	0.00e+00	778.00
IUUC-Olu-087698	Ostreococcus lucimarinus	28.90	6.00e-13	69.30
IUUC-Sha-107396	Sarcophilus harrisii	45.56	0.00e+00	818.00
IUUC-Sar-112978	Sorex araneus	50.81	0.00e+00	754.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence