iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ssc-116174

Ensembl Protein ID

ENSSSCP00000004502.2

UniProt Accession

F1S3R7; F1S3R7_PIG

Genbank Protein ID

ENSSSCP00000004502

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

CU633228

Gene Name

AHI1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000004166.2	ENSSSCT00000004605.2	ENSSSCP00000004502.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.20e-20	72.2	647	677
UBD/SH3	1.40e-14	54.1	1050	1102

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWD 29
           gH + +++l++ +d ++++++s Dgt ++W 
   Q: 647  GHLNIIYDLCWsNDdRYILTASSDGTARIWK 677
           79999*******777***************7 PP

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           +v +lydy+a+ +deLt+++Gd+++v    + +e+W++g +  +g++G fP+n v+
   Q: 1050 TVVALYDYTANRSDELTIHRGDIIRVF--FKDNEDWWYG-SVGKGQEGYFPANHVA 1102
           689***********************9..8999******.7************996 PP

Organism

Sus scrofa

Protein Sequence
(Fasta)

MPTVESEATV ETKVRVEELL KAHNDLIRER KKLKKKIGKS GEKISLKNVE VNRYFLTTFK 60
HGDLGTLRSN LQKIKETKSD AVSAANTNNP EKNMRVTKNK PRDPRSAHSE PDDDVSVEED 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCTCACTCCC CGCCCGCCCC GCCTGGGCTC TTTTTCCGAT CCCGGGTTTG GCTTCGGCGG 60
GACCGGCAGT TGGCTGCTCT GCGCCCTTTT CTCCGTGAGT ATCCTGCAGG CCTCCTGGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001452--SH3_domain
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50002--SH3
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00018--SH3_1
PF00400--WD40

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3
SM00320--WD40

Gene Ontology

GO:0005912--C:adherens junction
GO:0005911--C:cell-cell junction
GO:0005814--C:centriole
GO:0005813--C:centrosome
GO:0036064--C:ciliary basal body
GO:0005929--C:cilium
GO:0097730--C:non-motile cilium
GO:0034613--P:cellular protein localization
GO:0007417--P:central nervous system development
GO:0060271--P:cilium assembly
GO:0035844--P:cloaca development
GO:0001947--P:heart looping
GO:0030902--P:hindbrain development
GO:0070121--P:Kupffer's vesicle development
GO:0070986--P:left/right axis specification
GO:0001738--P:morphogenesis of a polarized epithelium
GO:0043066--P:negative regulation of apoptotic process
GO:0071599--P:otic vesicle development
GO:0035845--P:photoreceptor cell outer segment organization
GO:0030862--P:positive regulation of polarized epithelial cell differentiation
GO:0002092--P:positive regulation of receptor internalization
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0039023--P:pronephric duct morphogenesis
GO:0039008--P:pronephric nephron tubule morphogenesis
GO:0050795--P:regulation of behavior
GO:0010842--P:retina layer formation
GO:0065001--P:specification of axis polarity
GO:0007169--P:transmembrane receptor protein tyrosine kinase signaling pathway
GO:0016192--P:vesicle-mediated transport

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001943	Ailuropoda melanoleuca	86.22	0.00e+00	1675.00
IUUC-Apl-004057	Anas platyrhynchos	50.95	0.00e+00	1058.00
IUUC-Aca-004306	Anolis carolinensis	46.45	0.00e+00	951.00
IUUC-Ame-010981	Astyanax mexicanus	56.19	0.00e+00	772.00
IUUC-Bta-013129	Bos taurus	88.64	0.00e+00	1957.00
IUUC-Cja-018979	Callithrix jacchus	78.27	0.00e+00	1543.00
IUUC-Cfa-020121	Canis familiaris	84.89	0.00e+00	1884.00
IUUC-Cpo-022219	Cavia porcellus	77.51	0.00e+00	1313.00
IUUC-Csa-023991	Chlorocebus sabaeus	80.91	0.00e+00	1868.00
IUUC-Cho-024782	Choloepus hoffmanni	77.53	0.00e+00	957.00
IUUC-Cin-025149	Ciona intestinalis	39.46	4.00e-165	574.00
IUUC-Csv-026188	Ciona savignyi	38.62	2.00e-123	436.00
IUUC-Dre-028737	Danio rerio	50.00	0.00e+00	851.00
IUUC-Dno-029756	Dasypus novemcinctus	81.36	0.00e+00	1752.00
IUUC-Dor-030821	Dipodomys ordii	70.05	0.00e+00	1493.00
IUUC-Ete-032237	Echinops telfairi	78.12	0.00e+00	1593.00
IUUC-Eca-033491	Equus caballus	86.41	0.00e+00	1955.00
IUUC-Eeu-034812	Erinaceus europaeus	75.36	0.00e+00	956.00
IUUC-Fca-035868	Felis catus	84.70	0.00e+00	1809.00
IUUC-Fal-037571	Ficedula albicollis	55.16	0.00e+00	792.00
IUUC-Gmo-039358	Gadus morhua	50.71	0.00e+00	789.00
IUUC-Ggr-039923	Gaeumannomyces graminis	27.71	9.00e-16	79.30
IUUC-Gga-040233	Gallus gallus	56.57	0.00e+00	969.00
IUUC-Gac-041744	Gasterosteus aculeatus	49.11	0.00e+00	796.00
IUUC-Ggo-044766	Gorilla gorilla	81.32	0.00e+00	1893.00
IUUC-Hsa-046660	Homo sapiens	80.98	0.00e+00	1886.00
IUUC-Hvu-047828	Hordeum vulgare	26.21	1.00e-18	87.40
IUUC-Itr-048282	Ictidomys tridecemlineatus	82.50	0.00e+00	1885.00
IUUC-Loc-052658	Lepisosteus oculatus	52.44	0.00e+00	922.00
IUUC-Laf-053564	Loxodonta africana	89.25	0.00e+00	1488.00
IUUC-Mcc-055480	Macaca mulatta	81.33	0.00e+00	1883.00
IUUC-Meu-056362	Macropus eugenii	58.35	0.00e+00	806.00
IUUC-Mga-060033	Meleagris gallopavo	51.03	0.00e+00	1071.00
IUUC-Mmr-061075	Microcebus murinus	82.49	0.00e+00	1912.00
IUUC-Mdo-062818	Monodelphis domestica	53.41	0.00e+00	1159.00
IUUC-Mmu-063987	Mus musculus	77.58	0.00e+00	1587.00
IUUC-Mpu-066242	Mustela putorius furo	81.71	0.00e+00	1768.00
IUUC-Mlu-067123	Myotis lucifugus	81.22	0.00e+00	1757.00
IUUC-Ncr-068874	Neurospora crassa	26.94	1.00e-16	82.80
IUUC-Nle-069793	Nomascus leucogenys	80.90	0.00e+00	1892.00
IUUC-Opr-071110	Ochotona princeps	73.29	0.00e+00	845.00
IUUC-Ont-072179	Oreochromis niloticus	48.98	0.00e+00	822.00
IUUC-Oan-073201	Ornithorhynchus anatinus	64.72	9.00e-138	482.00
IUUC-Ocu-074224	Oryctolagus cuniculus	81.62	0.00e+00	1918.00
IUUC-Ola-086818	Oryzias latipes	52.53	8.00e-72	262.00
IUUC-Oga-088338	Otolemur garnettii	84.00	0.00e+00	1747.00
IUUC-Oar-089247	Ovis aries	85.43	0.00e+00	1988.00
IUUC-Ptr-090830	Pan troglodytes	81.70	0.00e+00	1846.00
IUUC-Pan-092469	Papio anubis	81.98	0.00e+00	1910.00
IUUC-Psi-093183	Pelodiscus sinensis	50.46	0.00e+00	1063.00
IUUC-Pma-094415	Petromyzon marinus	47.49	7.00e-159	553.00
IUUC-Pfo-096577	Poecilia formosa	47.77	0.00e+00	801.00
IUUC-Pab-098236	Pongo abelii	80.53	0.00e+00	1613.00
IUUC-Pca-100560	Procavia capensis	67.95	0.00e+00	1442.00
IUUC-Pva-102565	Pteropus vampyrus	77.37	0.00e+00	1324.00
IUUC-Rno-104881	Rattus norvegicus	77.39	0.00e+00	1605.00
IUUC-Sce-106320	Saccharomyces cerevisiae	26.86	2.00e-11	64.30
IUUC-Sha-106577	Sarcophilus harrisii	65.48	3.00e-166	577.00
IUUC-Sar-113265	Sorex araneus	72.29	0.00e+00	1532.00
IUUC-Tgu-116618	Taeniopygia guttata	48.69	0.00e+00	895.00
IUUC-Tru-117761	Takifugu rubripes	43.12	0.00e+00	672.00
IUUC-Tsy-119557	Tarsius syrichta	76.63	0.00e+00	906.00
IUUC-Tni-119782	Tetraodon nigroviridis	50.38	0.00e+00	803.00
IUUC-Tvi-122654	Trichoderma virens	26.89	1.00e-18	88.60
IUUC-Tbe-127529	Tupaia belangeri	68.03	8.00e-139	488.00
IUUC-Ttr-128444	Tursiops truncatus	84.35	0.00e+00	1890.00
IUUC-Vpa-130337	Vicugna pacos	78.71	0.00e+00	1725.00
IUUC-Xtr-132055	Xenopus tropicalis	57.74	0.00e+00	743.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence