iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ptr-091327

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AACZ03108829

Gene Name

SOCS7

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000009068.4	ENSPTRT00000016703.4	ENSPTRP00000015453.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	1.20e-14	53.9	317	364

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 2    sklwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedy 52
           +++ +++s++ SLqhLCR++Ir++++++++   + LPLPk L++Y++++ y
   Q: 317  LYPVSRFSNVKSLQHLCRFRIRQLVRIDHI---PDLPLPKPLISYIRKFYY 364
           567899*********************998...*************99976 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

PPPPPPGPLR PLAGPSRKGS FKIRLSRLFR TKSCNGGSGG GDGTGKRPSG ELAASAASLT 60
DMGGSAGREL DAGRKPKLTR TQSAFSPVSF SPLFTGETVS LVDVDISQRG LTSPHPPTPP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCGCCCCCGC CTCCTCCCGG GCCCCTCCGG CCACTCGCGG GTCCTTCTCG GAAGGGCTCC 60
TTCAAAATCC GCCTCAGTCG CCTCTTTCGC ACCAAGAGCT GCAACGGTGG CTCCGGCGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028423--SOCS7
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0004860--F:protein kinase inhibitor activity
GO:0019221--P:cytokine-mediated signaling pathway
GO:0045444--P:fat cell differentiation
GO:0008286--P:insulin receptor signaling pathway
GO:0035556--P:intracellular signal transduction
GO:0021819--P:layer formation in cerebral cortex
GO:0046426--P:negative regulation of JAK-STAT cascade
GO:0006469--P:negative regulation of protein kinase activity
GO:0016567--P:protein ubiquitination
GO:0021942--P:radial glia guided migration of Purkinje cell

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001668	Ailuropoda melanoleuca	98.94	0.00e+00	638.00
IUUC-Apl-003277	Anas platyrhynchos	91.78	1.00e-72	264.00
IUUC-Aca-004639	Anolis carolinensis	97.28	7.00e-108	382.00
IUUC-Ame-011301	Astyanax mexicanus	69.47	2.00e-130	459.00
IUUC-Bta-013483	Bos taurus	98.43	0.00e+00	630.00
IUUC-Cja-019765	Callithrix jacchus	99.69	1.00e-163	568.00
IUUC-Cfa-020109	Canis familiaris	98.41	0.00e+00	654.00
IUUC-Cpo-021555	Cavia porcellus	96.29	1.00e-178	619.00
IUUC-Csa-023580	Chlorocebus sabaeus	99.74	0.00e+00	643.00
IUUC-Cho-024431	Choloepus hoffmanni	99.21	7.00e-72	263.00
IUUC-Dre-028183	Danio rerio	71.46	2.00e-139	489.00
IUUC-Dno-028858	Dasypus novemcinctus	97.08	0.00e+00	628.00
IUUC-Dor-031071	Dipodomys ordii	79.25	2.00e-114	405.00
IUUC-Dme-031876	Drosophila melanogaster	43.65	4.00e-43	170.00
IUUC-Ete-032928	Echinops telfairi	70.86	2.00e-101	362.00
IUUC-Eca-033250	Equus caballus	93.67	2.00e-177	615.00
IUUC-Eeu-034946	Erinaceus europaeus	95.09	5.00e-49	188.00
IUUC-Fca-036589	Felis catus	98.67	0.00e+00	633.00
IUUC-Fal-037316	Ficedula albicollis	93.07	5.00e-112	396.00
IUUC-Gmo-038552	Gadus morhua	91.26	2.00e-53	200.00
IUUC-Gga-041248	Gallus gallus	96.76	1.00e-107	381.00
IUUC-Gac-041469	Gasterosteus aculeatus	83.47	7.00e-57	212.00
IUUC-Ggo-045282	Gorilla gorilla	100.00	2.00e-163	568.00
IUUC-Hsa-045926	Homo sapiens	100.00	0.00e+00	644.00
IUUC-Itr-048411	Ictidomys tridecemlineatus	98.31	6.00e-139	487.00
IUUC-Lch-049768	Latimeria chalumnae	79.47	4.00e-141	494.00
IUUC-Loc-051949	Lepisosteus oculatus	74.30	7.00e-129	454.00
IUUC-Laf-053410	Loxodonta africana	98.41	0.00e+00	654.00
IUUC-Mcc-054605	Macaca mulatta	88.97	5.00e-179	620.00
IUUC-Meu-056773	Macropus eugenii	79.87	1.00e-106	379.00
IUUC-Mvi-060489	Microbotryum violaceum	24.37	5.80e+00	25.40
IUUC-Mmr-060927	Microcebus murinus	99.21	0.00e+00	641.00
IUUC-Mdo-061892	Monodelphis domestica	93.40	2.00e-172	598.00
IUUC-Mmu-064246	Mus musculus	98.68	0.00e+00	635.00
IUUC-Mpu-065995	Mustela putorius furo	98.94	0.00e+00	635.00
IUUC-Mlu-067526	Myotis lucifugus	97.61	0.00e+00	649.00
IUUC-Nle-069317	Nomascus leucogenys	99.11	7.00e-166	576.00
IUUC-Ont-072258	Oreochromis niloticus	66.75	4.00e-117	415.00
IUUC-Oan-073703	Ornithorhynchus anatinus	80.49	1.00e-36	143.00
IUUC-Ocu-074577	Oryctolagus cuniculus	98.14	0.00e+00	650.00
IUUC-Oga-088426	Otolemur garnettii	98.40	0.00e+00	647.00
IUUC-Oar-089407	Ovis aries	98.43	0.00e+00	632.00
IUUC-Pan-092064	Papio anubis	99.47	0.00e+00	651.00
IUUC-Psi-093834	Pelodiscus sinensis	94.04	1.00e-153	535.00
IUUC-Pfo-097100	Poecilia formosa	62.50	1.00e-115	410.00
IUUC-Pab-097695	Pongo abelii	100.00	0.00e+00	635.00
IUUC-Pca-100569	Procavia capensis	90.13	3.00e-170	591.00
IUUC-Pva-102784	Pteropus vampyrus	97.61	0.00e+00	632.00
IUUC-Ptt-103775	Puccinia triticina	38.46	8.70e-01	29.30
IUUC-Rno-105485	Rattus norvegicus	98.95	0.00e+00	637.00
IUUC-Sha-106720	Sarcophilus harrisii	93.40	3.00e-173	601.00
IUUC-Sar-112975	Sorex araneus	84.28	5.00e-128	450.00
IUUC-Ssc-116369	Sus scrofa	97.90	0.00e+00	629.00
IUUC-Tgu-116867	Taeniopygia guttata	86.83	1.00e-124	439.00
IUUC-Tru-117562	Takifugu rubripes	77.53	3.00e-101	362.00
IUUC-Tsy-118999	Tarsius syrichta	93.40	6.00e-146	509.00
IUUC-Tni-120793	Tetraodon nigroviridis	68.80	7.00e-129	454.00
IUUC-Tbe-127671	Tupaia belangeri	99.07	2.00e-128	452.00
IUUC-Ttr-128491	Tursiops truncatus	82.22	1.00e-124	439.00
IUUC-Vpa-130104	Vicugna pacos	93.44	2.00e-171	595.00
IUUC-Xtr-132507	Xenopus tropicalis	80.05	2.00e-144	505.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence