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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Mmu-063847
Ensembl Protein ID ENSMUSP00000027888.6
UniProt Accession F8VQH0; F8VQH0_MOUSE
Genbank Protein ID ENSMUSP00000027888
Protein Name Tyrosine-protein kinase
Genbank Nucleotide ID AC114588
Gene Name Abl2
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000026596.13 ENSMUST00000173929.7 ENSMUSP00000133381.1
ENSMUSG00000026596.13 ENSMUST00000166172.8 ENSMUSP00000126181.2
ENSMUSG00000026596.13 ENSMUST00000027888.12 ENSMUSP00000027888.6
ENSMUSG00000026596.13 ENSMUST00000190749.1 ENSMUSP00000140125.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitemiRTarBasemicroRNATRANSFAC
RepTarRAID2
Protein-protein Interaction
HINT
Protein 3D Structure
PDBMMDB
Post-translational Modifications (PTMs)
PHOSIDA
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/SH3 4.60e-12 46.8 109 166
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/SH3
   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
            +++ +lyd+ a+ d++L+++kG++++v+  ++q+++W +     ++ +G +P+n+++ ++
   Q: 109  PNLFVALYDFVASGDNTLSITKGEKLRVL-GYNQNGEWSEV--RSKNGQGWVPSNYITPVN 166
           67899************************.*********98..788899*********997 PP
   
Organism Mus musculus
Protein Sequence
(Fasta)
MGQQVGRVGE APGLQQPQPR GIRGSSAARP SGRRRDPAGR TADAGFNVFT QHDHFASCVE 60
DGFEGDKTGG SSPEVLHRPF GCDAESQALN EAIRWSSKEN LLGATESDPN LFVALYDFVA 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063847|UBD,SH3|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CTGTGCTCGG TGGTTTAAAG ATGGCGGCGG CGGCTGGGGC GAGGAGCCGC CGGAGGGGGA 60
GGGAGAAGGA GAGTCTGTGA GTCGCTGGGA GGCAGCGCGG CAGCGGCTCC GAGGAGTCCG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063847|UBD,SH3|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase
Interpro

IPR015015--F-actin_binding
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom
PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3
Pfam

PF08919--F_actin_bind
PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1
PRINTS

PR00401--SH2DOMAIN
PR00109--TYRKINASE
SMART

SM00808--FABD
SM00252--SH2
SM00326--SH3
SM00219--TyrKc
Gene Ontology

GO:0005623--C:cell
GO:0005524--F:ATP binding
GO:0000287--F:magnesium ion binding
GO:0030145--F:manganese ion binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0071300--P:cellular response to retinoic acid
GO:0007204--P:positive regulation of cytosolic calcium ion concentration
GO:0010976--P:positive regulation of neuron projection development
GO:0051353--P:positive regulation of oxidoreductase activity
GO:0010863--P:positive regulation of phospholipase C activity
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002263 Ailuropoda melanoleuca 93.97 0.00e+00 1892.00
IUUC-Apl-003389 Anas platyrhynchos 83.86 0.00e+00 1677.00
IUUC-Ame-010629 Astyanax mexicanus 58.43 0.00e+00 1049.00
IUUC-Bta-013370 Bos taurus 93.50 0.00e+00 2001.00
IUUC-Cja-018894 Callithrix jacchus 92.47 0.00e+00 1901.00
IUUC-Cfa-020398 Canis familiaris 95.91 0.00e+00 1222.00
IUUC-Cpo-022367 Cavia porcellus 92.56 0.00e+00 1450.00
IUUC-Csa-023386 Chlorocebus sabaeus 94.15 0.00e+00 1884.00
IUUC-Cho-024714 Choloepus hoffmanni 94.73 0.00e+00 1340.00
IUUC-Dre-027741 Danio rerio 66.67 0.00e+00 1362.00
IUUC-Dno-029246 Dasypus novemcinctus 90.54 0.00e+00 1904.00
IUUC-Dor-030416 Dipodomys ordii 87.08 0.00e+00 1784.00
IUUC-Ete-032899 Echinops telfairi 74.42 0.00e+00 777.00
IUUC-Eca-033387 Equus caballus 92.91 0.00e+00 1893.00
IUUC-Eeu-035058 Erinaceus europaeus 83.38 0.00e+00 1776.00
IUUC-Fca-036578 Felis catus 87.83 0.00e+00 1712.00
IUUC-Fal-037491 Ficedula albicollis 86.59 0.00e+00 1801.00
IUUC-Gmo-038509 Gadus morhua 77.26 0.00e+00 1117.00
IUUC-Gga-040638 Gallus gallus 84.27 0.00e+00 1749.00
IUUC-Gac-042550 Gasterosteus aculeatus 67.50 0.00e+00 1292.00
IUUC-Ggo-044487 Gorilla gorilla 94.34 0.00e+00 1982.00
IUUC-Hsa-046636 Homo sapiens 94.26 0.00e+00 1982.00
IUUC-Itr-048685 Ictidomys tridecemlineatus 94.52 0.00e+00 1928.00
IUUC-Lch-049530 Latimeria chalumnae 74.11 0.00e+00 1542.00
IUUC-Loc-051933 Lepisosteus oculatus 70.07 0.00e+00 1413.00
IUUC-Laf-053802 Loxodonta africana 94.01 0.00e+00 2045.00
IUUC-Mcc-054836 Macaca mulatta 94.09 0.00e+00 1986.00
IUUC-Mga-059277 Meleagris gallopavo 86.31 0.00e+00 1761.00
IUUC-Mmr-061206 Microcebus murinus 92.65 0.00e+00 1975.00
IUUC-Mdo-062281 Monodelphis domestica 92.44 0.00e+00 1211.00
IUUC-Mpu-066309 Mustela putorius furo 95.20 0.00e+00 1317.00
IUUC-Mlu-068070 Myotis lucifugus 93.52 0.00e+00 1885.00
IUUC-Nle-070062 Nomascus leucogenys 95.49 0.00e+00 1274.00
IUUC-Opr-070534 Ochotona princeps 87.42 0.00e+00 974.00
IUUC-Ont-072440 Oreochromis niloticus 67.95 0.00e+00 1243.00
IUUC-Oan-073526 Ornithorhynchus anatinus 87.04 0.00e+00 1694.00
IUUC-Ocu-074051 Oryctolagus cuniculus 93.43 0.00e+00 1788.00
IUUC-Oin-079172 Oryza indica 34.39 2.00e-23 104.00
IUUC-Olo-080286 Oryza longistaminata 34.39 2.00e-23 104.00
IUUC-Opu-083538 Oryza punctata 34.84 3.00e-23 103.00
IUUC-Oru-084741 Oryza rufipogon 34.39 2.00e-23 104.00
IUUC-Osa-085779 Oryza sativa 34.39 2.00e-23 104.00
IUUC-Ola-086752 Oryzias latipes 95.04 0.00e+00 910.00
IUUC-Oga-088767 Otolemur garnettii 86.71 0.00e+00 1679.00
IUUC-Oar-089800 Ovis aries 93.62 0.00e+00 1900.00
IUUC-Ptr-090857 Pan troglodytes 95.49 0.00e+00 1273.00
IUUC-Pan-092279 Papio anubis 92.31 0.00e+00 1918.00
IUUC-Psi-093573 Pelodiscus sinensis 87.26 0.00e+00 1742.00
IUUC-Pfo-096543 Poecilia formosa 71.71 0.00e+00 1144.00
IUUC-Pab-097949 Pongo abelii 91.39 0.00e+00 1886.00
IUUC-Pca-100370 Procavia capensis 91.32 0.00e+00 1361.00
IUUC-Pva-103220 Pteropus vampyrus 83.54 0.00e+00 1689.00
IUUC-Rno-105924 Rattus norvegicus 94.33 0.00e+00 1984.00
IUUC-Sha-107114 Sarcophilus harrisii 85.43 0.00e+00 1340.00
IUUC-Ssc-115968 Sus scrofa 93.07 0.00e+00 2032.00
IUUC-Tgu-117301 Taeniopygia guttata 86.33 0.00e+00 1723.00
IUUC-Tru-118410 Takifugu rubripes 66.59 0.00e+00 1387.00
IUUC-Tni-119991 Tetraodon nigroviridis 70.73 0.00e+00 1268.00
IUUC-Tbe-127362 Tupaia belangeri 89.19 0.00e+00 1811.00
IUUC-Ttr-129291 Tursiops truncatus 93.43 0.00e+00 1872.00
IUUC-Vpa-130800 Vicugna pacos 92.16 0.00e+00 1450.00
IUUC-Xtr-132965 Xenopus tropicalis 71.67 0.00e+00 1272.00
Created Date 25-Jun-2017

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