iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089370

Ensembl Protein ID

ENSOARP00000010689.1

UniProt Accession

W5PJR8; W5PJR8_SHEEP

Genbank Protein ID

ENSOARP00000010689

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01033573

Gene Name

UBE2L6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000009969.1	ENSOART00000010846.1	ENSOARP00000010689.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	1.30e-36	125.5	9	141

Active Site

Position(s)	Description	Evidence
86	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 4    kelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeeekW 92
           +el++l+k+ p++++  +++e+++  w++l+l pe+ pY+ ++F+l i+fp++YPf+PP+vkf+t+i+hPnv+++G+vCl +++ +++W
   Q: 9    QELEDLQKQLPKYLRHLCSEEDNVLVWHALLL-PERPPYNLKAFRLCISFPREYPFQPPTVKFTTRIYHPNVDRDGRVCLPLIN-KKNW 95
           79******************************.**************************************************6.9*** PP
   S: 93   spalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           ++ ++  +vl +++ l+++p+p +p++ e ae+l++++e ++++++
   Q: 96   KASTKTCQVLEALNVLVNQPEPGEPVRLELAEQLTQDPELFDRTAQ 141
           ******************************************9986 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

PAACSVPLQE LEDLQKQLPK YLRHLCSEED NVLVWHALLL PERPPYNLKA FRLCISFPRE 60
YPFQPPTVKF TTRIYHPNVD RDGRVCLPLI NKKNWKASTK TCQVLEALNV LVNQPEPGEP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCAGCTGCCT GCTCTGTGCC CCTGCAGGAG CTGGAAGACC TGCAGAAGCA GCTTCCCAAG 60
TACCTGCGGC ACCTGTGCAG CGAGGAGGAC AACGTGCTGG TGTGGCACGC GCTGCTGCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005524--F:ATP binding
GO:0042296--F:ISG15 transferase activity
GO:0032020--P:ISG15-protein conjugation
GO:0019941--P:modification-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001818	Ailuropoda melanoleuca	68.28	2.00e-56	210.00
IUUC-Bta-012539	Bos taurus	93.10	2.00e-78	283.00
IUUC-Cja-019456	Callithrix jacchus	70.34	2.00e-59	221.00
IUUC-Cfa-021275	Canis familiaris	71.72	5.00e-59	219.00
IUUC-Cpo-022261	Cavia porcellus	64.83	3.00e-50	190.00
IUUC-Csa-023794	Chlorocebus sabaeus	70.34	2.00e-58	217.00
IUUC-Cho-024821	Choloepus hoffmanni	69.44	3.00e-57	213.00
IUUC-Dno-029632	Dasypus novemcinctus	73.10	7.00e-61	225.00
IUUC-Dor-030595	Dipodomys ordii	68.75	1.00e-42	164.00
IUUC-Eca-033746	Equus caballus	73.79	2.00e-60	224.00
IUUC-Fca-035417	Felis catus	71.72	3.00e-59	219.00
IUUC-Ggo-045537	Gorilla gorilla	68.49	2.00e-57	214.00
IUUC-Hsa-045943	Homo sapiens	69.18	9.00e-58	215.00
IUUC-Itr-048889	Ictidomys tridecemlineatus	64.14	1.00e-52	198.00
IUUC-Laf-053524	Loxodonta africana	66.21	2.00e-50	190.00
IUUC-Mcc-054818	Macaca mulatta	70.34	3.00e-58	216.00
IUUC-Meu-055936	Macropus eugenii	56.36	2.00e-31	127.00
IUUC-Mmr-060799	Microcebus murinus	71.03	2.00e-58	217.00
IUUC-Mmu-063359	Mus musculus	67.59	4.00e-54	202.00
IUUC-Mpu-066122	Mustela putorius furo	65.00	2.00e-52	197.00
IUUC-Mlu-067283	Myotis lucifugus	65.79	1.00e-53	201.00
IUUC-Nle-069829	Nomascus leucogenys	71.03	2.00e-59	221.00
IUUC-Opr-071062	Ochotona princeps	65.79	3.00e-54	203.00
IUUC-Oan-073297	Ornithorhynchus anatinus	68.75	3.00e-36	143.00
IUUC-Ocu-074709	Oryctolagus cuniculus	69.13	1.00e-56	211.00
IUUC-Oga-088256	Otolemur garnettii	66.90	2.00e-56	210.00
IUUC-Ptr-091324	Pan troglodytes	69.18	9.00e-58	215.00
IUUC-Pan-092601	Papio anubis	72.11	1.00e-59	221.00
IUUC-Pab-098184	Pongo abelii	69.66	4.00e-58	216.00
IUUC-Pca-101080	Procavia capensis	68.75	4.00e-56	209.00
IUUC-Pva-102211	Pteropus vampyrus	70.54	4.00e-43	166.00
IUUC-Rno-104863	Rattus norvegicus	67.59	2.00e-55	207.00
IUUC-Sha-107162	Sarcophilus harrisii	55.26	8.00e-45	172.00
IUUC-Ssc-115506	Sus scrofa	77.24	2.00e-64	237.00
IUUC-Tsy-118811	Tarsius syrichta	60.84	9.00e-47	178.00
IUUC-Ttr-129266	Tursiops truncatus	80.00	5.00e-66	242.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence