iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000009717.1	ENSSHAT00000011392.1	ENSSHAP00000011297.1
ENSSHAG00000009717.1	ENSSHAT00000011393.1	ENSSHAP00000011298.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	7.50e-34	114.5	208	245
UBD/Beta-Prp	4.20e-48	164.2	35	294
ULD/UBL/SUMO	4.40e-61	203.8	559	645

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gHtd v +l +  d t  +sGs Dgti++W+l +++++
   Q: 208  GHTDNVKALLLnRDgTQCLSGSSDGTIRLWSLGQQRCI 245
           8********88*888*****************999997 PP

UBD/Beta-Prp

   S: 15   cvkfspdksllatgsrdgtikvwdvttgkl...lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlsl 100
           +++  p  + l+t++rd+ i++w+v++ k    ++s++ h++ v+++ +  +gk+l+++s+D t+kvw+  +g c++tl+ h+d+v +l
   Q: 35   ALQLDPALNRLFTAGRDSIIRIWSVSQHKQdpyIASMEHHTDWVNDIVLCCNGKTLISASSDTTVKVWNAHKGFCMSTLRTHKDYVKAL 123
           56677788999****************999999******************************************************** PP
   S: 101  sfspsgdklvsGshdrtirvwdletgqclee........tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtd 181
           ++ ++++ ++s++ dr i +wd++t + l +         lsg+++++ ++++++ g ++vsGs+ +++r+Wd +t   l +l+g htd
   Q: 124  AYAKDKELVASAGLDRQIFLWDVNTLTALTAsnntvttsSLSGNKDSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKG-HTD 211
           *****************************999*******************************************9999999*99.*** PP
   S: 182  svyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhn 264
            v+ l ++++g++++sgs dgt++lw+l +++c+ t++ h++ v+ +++ +  ++++sg+ D+ i++ dlr+ d+   +  ++
   Q: 212  NVKALLLNRDGTQCLSGSSDGTIRLWSLGQQRCIATYRVHDEGVWALQVNEAFTHVYSGGRDRKIYCTDLRNPDIRVLICEEK 294
           *********************************************************************99988877666666 PP

ULD/UBL/SUMO

   S: 1    eskffkapvslkvagqdGsevlfklklsa....qlkklmeavYvkrinldensvrfv.fngqkireqetpeelevededkiellcqk 82
           ++kf+k+p++l++++++G+++l+k++lsa    q++k+me+vY+k+inld +s++++ +n++k +eqe++e+++v++e+kiellcq+
   Q: 559  MPKFNKIPFYLQPHSSSGAKTLKKDRLSAsdmlQVRKVMEHVYEKIINLDSESQTTSsSNNEKTGEQEKEEDIAVLAEEKIELLCQD 645
           8********************************************************9***************************97 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

EVIIRLENRE SKEKIQVSYV IRDEVEKCNR NGVNALQLDP ALNRLFTAGR DSIIRIWSVS 60
QHKQDPYIAS MEHHTDWVND IVLCCNGKTL ISASSDTTVK VWNAHKGFCM STLRTHKDYV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGAGGAAAA TGAAGGAAGA AGGCAGAGGT TGTGACTTGG CCAGGGTCAT ATATAGCTGG 60
TAAGTGGCTG AGGCCAGATC GTGTATAATT CTAACATATG CCTAGAAGAG GCCCTGCTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR021772--DUF3337
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF11816--DUF3337
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005634--C:nucleus
GO:0000724--P:double-strand break repair via homologous recombination
GO:0048568--P:embryonic organ development
GO:0048872--P:homeostasis of number of cells
GO:0035264--P:multicellular organism growth
GO:0050679--P:positive regulation of epithelial cell proliferation
GO:0016579--P:protein deubiquitination
GO:1902525--P:regulation of protein monoubiquitination
GO:0072520--P:seminiferous tubule development
GO:0007338--P:single fertilization
GO:0048705--P:skeletal system morphogenesis
GO:0043588--P:skin development
GO:0007283--P:spermatogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001160	Aegilops tauschii	40.36	8.00e-97	348.00
IUUC-Aml-001533	Ailuropoda melanoleuca	96.72	0.00e+00	1173.00
IUUC-Atr-003009	Amborella trichopoda	33.56	2.00e-102	366.00
IUUC-Apl-003709	Anas platyrhynchos	97.67	0.00e+00	659.00
IUUC-Aca-004875	Anolis carolinensis	96.72	0.00e+00	1209.00
IUUC-Aly-005464	Arabidopsis lyrata	40.56	1.00e-93	337.00
IUUC-Ath-006969	Arabidopsis thaliana	39.96	3.00e-89	322.00
IUUC-Acl-008203	Aspergillus clavatus	35.40	8.00e-48	185.00
IUUC-Afl-008571	Aspergillus flavus	34.91	4.00e-47	183.00
IUUC-Afu-009072	Aspergillus fumigatus	35.33	1.00e-45	178.00
IUUC-Ani-009413	Aspergillus nidulans	36.13	2.00e-48	187.00
IUUC-Ang-009571	Aspergillus niger	35.02	7.00e-45	176.00
IUUC-Aor-010064	Aspergillus oryzae	35.52	2.00e-47	184.00
IUUC-Ate-010463	Aspergillus terreus	35.22	2.00e-47	184.00
IUUC-Ame-010875	Astyanax mexicanus	94.11	0.00e+00	1031.00
IUUC-Bgr-012288	Blumeria graminis	33.80	4.00e-42	166.00
IUUC-Bta-013379	Bos taurus	96.72	0.00e+00	1169.00
IUUC-Bci-013859	Botrytis cinerea	32.29	5.00e-41	163.00
IUUC-Bdi-014645	Brachypodium distachyon	35.25	5.00e-103	368.00
IUUC-Bol-016450	Brassica oleracea	34.06	8.00e-93	334.00
IUUC-Bra-017237	Brassica rapa	34.04	7.00e-95	341.00
IUUC-Cel-018656	Caenorhabditis elegans	43.62	3.00e-145	508.00
IUUC-Cja-018804	Callithrix jacchus	96.41	0.00e+00	1167.00
IUUC-Cfa-020076	Canis familiaris	96.88	0.00e+00	1172.00
IUUC-Cpo-021721	Cavia porcellus	96.68	0.00e+00	1145.00
IUUC-Cre-022779	Chlamydomonas reinhardtii	31.20	3.00e-41	164.00
IUUC-Csa-023188	Chlorocebus sabaeus	96.88	0.00e+00	1172.00
IUUC-Cho-024932	Choloepus hoffmanni	95.79	0.00e+00	1175.00
IUUC-Cin-025591	Ciona intestinalis	56.33	0.00e+00	680.00
IUUC-Cgl-026540	Colletotrichum gloeosporioides	27.55	1.00e-20	95.10
IUUC-Cne-026819	Cryptococcus neoformans	35.53	1.00e-34	142.00
IUUC-Cme-027188	Cyanidioschyzon merolae	31.57	2.00e-61	230.00
IUUC-Dre-027926	Danio rerio	91.73	0.00e+00	1187.00
IUUC-Dno-029960	Dasypus novemcinctus	95.94	0.00e+00	1161.00
IUUC-Dor-030933	Dipodomys ordii	94.01	0.00e+00	708.00
IUUC-Dse-031532	Dothistroma septosporum	35.28	4.00e-46	180.00
IUUC-Dme-032168	Drosophila melanogaster	55.96	0.00e+00	641.00
IUUC-Ete-033107	Echinops telfairi	95.09	0.00e+00	1120.00
IUUC-Eca-034028	Equus caballus	97.04	0.00e+00	1174.00
IUUC-Eeu-034894	Erinaceus europaeus	94.81	0.00e+00	835.00
IUUC-Fca-035619	Felis catus	96.49	0.00e+00	914.00
IUUC-Fal-036869	Ficedula albicollis	97.78	0.00e+00	1201.00
IUUC-Fox-037907	Fusarium oxysporum	32.67	5.00e-41	163.00
IUUC-Fso-038101	Fusarium solani	32.95	1.00e-40	161.00
IUUC-Gmo-038627	Gadus morhua	93.60	0.00e+00	1199.00
IUUC-Ggr-039995	Gaeumannomyces graminis	29.75	4.00e-41	163.00
IUUC-Gga-040555	Gallus gallus	96.73	0.00e+00	1204.00
IUUC-Gac-042497	Gasterosteus aculeatus	93.60	0.00e+00	1174.00
IUUC-Gma-043089	Glycine max	34.60	2.00e-101	363.00
IUUC-Ggo-045561	Gorilla gorilla	96.88	0.00e+00	1172.00
IUUC-Hsa-045710	Homo sapiens	96.88	0.00e+00	1172.00
IUUC-Hvu-047730	Hordeum vulgare	34.69	6.00e-76	278.00
IUUC-Itr-049030	Ictidomys tridecemlineatus	97.52	0.00e+00	828.00
IUUC-Kpa-049237	Komagataella pastoris	30.46	9.00e-30	125.00
IUUC-Lch-049507	Latimeria chalumnae	95.94	0.00e+00	1180.00
IUUC-Lpe-051608	Leersia perrieri	36.69	3.00e-104	372.00
IUUC-Loc-052373	Lepisosteus oculatus	92.07	0.00e+00	1158.00
IUUC-Lma-053025	Leptosphaeria maculans	35.73	3.00e-49	190.00
IUUC-Laf-053706	Loxodonta africana	97.31	0.00e+00	1160.00
IUUC-Mcc-055046	Macaca mulatta	96.88	0.00e+00	1172.00
IUUC-Meu-056840	Macropus eugenii	81.63	5.00e-152	531.00
IUUC-Mor-057284	Magnaporthe oryzae	31.73	7.00e-43	169.00
IUUC-Mpo-057418	Magnaporthe poae	29.75	1.00e-40	162.00
IUUC-Mtr-058571	Medicago truncatula	35.54	2.00e-99	357.00
IUUC-Mla-059101	Melampsora laricipopulina	45.10	8.00e-46	179.00
IUUC-Mga-059297	Meleagris gallopavo	96.73	0.00e+00	1204.00
IUUC-Mvi-060419	Microbotryum violaceum	41.10	2.00e-38	154.00
IUUC-Mmr-061196	Microcebus murinus	90.82	0.00e+00	1072.00
IUUC-Mdo-062762	Monodelphis domestica	94.46	0.00e+00	1207.00
IUUC-Mmu-063915	Mus musculus	95.63	0.00e+00	1188.00
IUUC-Mac-065434	Musa acuminata	36.08	5.00e-101	362.00
IUUC-Mpu-065999	Mustela putorius furo	95.73	0.00e+00	809.00
IUUC-Mlu-068226	Myotis lucifugus	96.72	0.00e+00	1167.00
IUUC-Nfi-068416	Neosartorya fischeri	29.56	1.00e-55	211.00
IUUC-Ncr-068825	Neurospora crassa	31.52	5.00e-40	159.00
IUUC-Nle-069416	Nomascus leucogenys	96.88	0.00e+00	1172.00
IUUC-Opr-070515	Ochotona princeps	92.51	0.00e+00	1100.00
IUUC-Ont-072052	Oreochromis niloticus	91.01	0.00e+00	1113.00
IUUC-Oan-073636	Ornithorhynchus anatinus	94.30	0.00e+00	1186.00
IUUC-Ocu-074799	Oryctolagus cuniculus	96.72	0.00e+00	1170.00
IUUC-Oba-075146	Oryza barthii	37.02	1.00e-104	373.00
IUUC-Obr-076699	Oryza brachyantha	35.53	4.00e-104	372.00
IUUC-Ogl-077883	Oryza glaberrima	34.04	3.00e-59	222.00
IUUC-Ogu-078114	Oryza glumaepatula	36.74	6.00e-104	371.00
IUUC-Oin-079575	Oryza indica	35.75	4.00e-105	375.00
IUUC-Olo-080531	Oryza longistaminata	33.84	3.00e-94	339.00
IUUC-Ome-081368	Oryza meridionalis	41.00	8.00e-98	351.00
IUUC-Oni-082457	Oryza nivara	37.02	1.00e-104	374.00
IUUC-Opu-084050	Oryza punctata	36.73	5.00e-103	368.00
IUUC-Oru-084330	Oryza rufipogon	37.02	2.00e-104	373.00
IUUC-Osa-085408	Oryza sativa	35.75	4.00e-105	375.00
IUUC-Ola-087546	Oryzias latipes	93.06	0.00e+00	1175.00
IUUC-Olu-087710	Ostreococcus lucimarinus	32.50	3.00e-79	289.00
IUUC-Oga-087998	Otolemur garnettii	97.48	0.00e+00	1168.00
IUUC-Oar-090303	Ovis aries	96.72	0.00e+00	1169.00
IUUC-Ptr-090588	Pan troglodytes	96.88	0.00e+00	1172.00
IUUC-Pan-092722	Papio anubis	96.88	0.00e+00	1172.00
IUUC-Psi-093911	Pelodiscus sinensis	96.13	0.00e+00	1205.00
IUUC-Pma-094580	Petromyzon marinus	87.25	0.00e+00	1110.00
IUUC-Pno-095085	Phaeosphaeria nodorum	35.87	5.00e-45	176.00
IUUC-Ppa-095594	Physcomitrella patens	37.14	6.00e-105	374.00
IUUC-Pfo-096994	Poecilia formosa	92.88	0.00e+00	1166.00
IUUC-Pab-097586	Pongo abelii	96.88	0.00e+00	1170.00
IUUC-Pop-099740	Populus trichocarpa	35.81	4.00e-96	345.00
IUUC-Pca-100458	Procavia capensis	98.56	3.00e-106	379.00
IUUC-Ppe-102060	Prunus persica	33.97	4.00e-99	355.00
IUUC-Pva-102698	Pteropus vampyrus	91.89	0.00e+00	1153.00
IUUC-Pgr-103649	Puccinia graminis	38.70	1.00e-47	185.00
IUUC-Ptt-103910	Puccinia triticina	43.50	5.00e-53	203.00
IUUC-Pte-104181	Pyrenophora teres	36.64	5.00e-49	190.00
IUUC-Pyt-104439	Pyrenophora triticirepentis	36.34	1.00e-48	188.00
IUUC-Rno-104978	Rattus norvegicus	96.83	0.00e+00	1183.00
IUUC-Sja-107716	Schizosaccharomyces japonicus	30.36	2.00e-59	224.00
IUUC-Spo-108325	Schizosaccharomyces pombe	30.34	2.00e-52	201.00
IUUC-Ssl-108542	Sclerotinia sclerotiorum	28.78	7.00e-45	176.00
IUUC-Smo-109427	Selaginella moellendorffii	35.94	1.00e-99	357.00
IUUC-Sit-110755	Setaria italica	36.04	8.00e-105	374.00
IUUC-Sly-111099	Solanum lycopersicum	34.08	4.00e-99	355.00
IUUC-Sar-113408	Sorex araneus	96.36	0.00e+00	736.00
IUUC-Sbi-113789	Sorghum bicolor	35.80	1.00e-101	364.00
IUUC-Sre-114998	Sporisorium reilianum	40.26	1.00e-52	202.00
IUUC-Ssc-115434	Sus scrofa	96.88	0.00e+00	1172.00
IUUC-Tgu-116517	Taeniopygia guttata	96.72	0.00e+00	1207.00
IUUC-Tru-118174	Takifugu rubripes	93.63	0.00e+00	1176.00
IUUC-Tsy-118935	Tarsius syrichta	96.57	0.00e+00	1196.00
IUUC-Tni-119744	Tetraodon nigroviridis	94.07	0.00e+00	1146.00
IUUC-Tca-121360	Theobroma cacao	34.19	1.00e-103	370.00
IUUC-Tre-122198	Trichoderma reesei	32.47	5.00e-43	169.00
IUUC-Tvi-122389	Trichoderma virens	32.76	2.00e-43	171.00
IUUC-Tae-125576	Triticum aestivum	34.80	3.00e-104	372.00
IUUC-Tur-126699	Triticum urartu	34.56	1.00e-103	370.00
IUUC-Tme-126932	Tuber melanosporum	31.21	5.00e-54	206.00
IUUC-Tbe-127267	Tupaia belangeri	97.20	0.00e+00	686.00
IUUC-Ttr-129153	Tursiops truncatus	96.26	0.00e+00	1200.00
IUUC-Uma-129604	Ustilago maydis	38.74	3.00e-50	194.00
IUUC-Vda-129925	Verticillium dahliae	34.99	3.00e-46	180.00
IUUC-Vpa-130553	Vicugna pacos	96.35	0.00e+00	947.00
IUUC-Vvi-130995	Vitis vinifera	35.63	2.00e-99	356.00
IUUC-Xtr-132346	Xenopus tropicalis	92.68	0.00e+00	1142.00
IUUC-Xma-134266	Xiphophorus maculatus	91.74	2.00e-174	604.00
IUUC-Yli-134451	Yarrowia lipolytica	28.08	5.00e-39	155.00
IUUC-Zma-135647	Zea mays	35.61	7.00e-103	368.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence