iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Fca-036307

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02077415

Gene Name

EML6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000018728.2	ENSFCAT00000018916.2	ENSFCAP00000015318.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.90e-59	194.4	105	144
UBD/Beta-Prp	1.90e-134	447.6	57	264

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdD..gtikvWDlrtgvllk 37
           Ht +v claf sd  +l+s + D  +t+ +WD+r+g+ll 
   Q: 105  HTHGVACLAFdSDgQRLASVGLDakNTVCIWDWRKGKLLA 144
           99*********999*******9999***********9875 PP

UBD/Beta-Prp

   S: 5    lkghhksvitcvkfspdksllatgs..rdgtikvwdvttgkllrsl.sgheaevtavkfspdgkilvtgseD..rtikvwdlstgkcvh 88
           + gh+++ i+ ++ +pdk+l+atg   +   i +wd  + ++++ l   h+ +v+++ f++dg+ l++++ D  +t+++wd ++gk + 
   Q: 57   FLGHNDDIIS-LALHPDKTLVATGQvgKEPYICIWDSYNVQTVSILkDVHTHGVACLAFDSDGQRLASVGLDakNTVCIWDWRKGKLLA 144
           5578888888.9999********96115567***************777**************************************** PP
   S: 89   tlkghedsvlslsfspsg.dklvsGshdrtirvwdletgqclee..tlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllr 173
           + +gh+d++ ++s++p++ +++vs   ++ i+ w l  +    +  ++ ++ ++ +++++ + + ++  sG+l++ + +W+    +l+r
   Q: 145  SATGHSDRIFDISWDPYQpNRVVSC-GVKHIKFWTLCGNALTAKrgIFGKTGDLQTILCLACAKdDITYSGALNGDIYVWKG--LNLVR 230
           ****************994555555.5*******99999999889966666666666666666559**************66..99*** PP
   S: 174  tltgghtdsvyslsfdsngkelvsgsldgtvklwdl 209
           t +g+h   + s+   ++g  +++g++dg ++lwd 
   Q: 231  TIQGAHSAGIFSMYACEEG--FATGGRDGCIRLWDT 264
           *************999965..*************96 PP

Organism

Felis catus

Protein Sequence
(Fasta)

MADRTAPSCQ LRLEWVYGYR GHQCRNNLYY TAGKEVVYFV AGVGVVYNTR EHSQKFFLGH 60
NDDIISLALH PDKTLVATGQ VGKEPYICIW DSYNVQTVSI LKDVHTHGVA CLAFDSDGQR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGATC GGACAGCTCC CAGCTGCCAG CTCCGGCTGG AGTGGGTGTA CGGGTACCGG 60
GGTCACCAGT GCCGCAACAA CCTGTACTAC ACGGCCGGCA AGGAGGTGGT CTACTTTGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR024977--Apc4_WD40_dom
IPR011048--Haem_d1
IPR005108--HELP
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF03451--HELP
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0015630--C:microtubule cytoskeleton
GO:0008017--F:microtubule binding

KEGG

fca:101091187

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001387	Ailuropoda melanoleuca	99.13	0.00e+00	3888.00
IUUC-Apl-003604	Anas platyrhynchos	94.25	0.00e+00	3703.00
IUUC-Aca-004572	Anolis carolinensis	90.26	0.00e+00	3596.00
IUUC-Ame-010713	Astyanax mexicanus	80.59	0.00e+00	3225.00
IUUC-Bta-012812	Bos taurus	98.52	0.00e+00	3868.00
IUUC-Cja-019191	Callithrix jacchus	97.47	0.00e+00	3815.00
IUUC-Cfa-020041	Canis familiaris	99.34	0.00e+00	3615.00
IUUC-Cpo-022304	Cavia porcellus	72.30	0.00e+00	2887.00
IUUC-Cre-022931	Chlamydomonas reinhardtii	35.12	4.00e-102	368.00
IUUC-Csa-023689	Chlorocebus sabaeus	97.12	0.00e+00	3725.00
IUUC-Cho-025038	Choloepus hoffmanni	98.04	0.00e+00	1503.00
IUUC-Cin-025205	Ciona intestinalis	62.08	0.00e+00	2583.00
IUUC-Csv-026014	Ciona savignyi	63.44	0.00e+00	2602.00
IUUC-Dre-028772	Danio rerio	74.29	0.00e+00	3093.00
IUUC-Dno-029982	Dasypus novemcinctus	96.12	0.00e+00	3672.00
IUUC-Dor-030980	Dipodomys ordii	69.86	0.00e+00	1300.00
IUUC-Ete-032554	Echinops telfairi	72.09	0.00e+00	831.00
IUUC-Eca-034161	Equus caballus	97.16	0.00e+00	3699.00
IUUC-Eeu-035180	Erinaceus europaeus	63.67	0.00e+00	1149.00
IUUC-Fal-037332	Ficedula albicollis	92.94	0.00e+00	3622.00
IUUC-Gmo-039057	Gadus morhua	74.99	0.00e+00	2999.00
IUUC-Gga-041095	Gallus gallus	75.28	0.00e+00	2241.00
IUUC-Gac-042555	Gasterosteus aculeatus	80.50	0.00e+00	3241.00
IUUC-Ggo-045107	Gorilla gorilla	98.21	0.00e+00	3857.00
IUUC-Hsa-046482	Homo sapiens	98.31	0.00e+00	3862.00
IUUC-Itr-049023	Ictidomys tridecemlineatus	96.27	0.00e+00	3725.00
IUUC-Lch-050306	Latimeria chalumnae	73.30	0.00e+00	2760.00
IUUC-Loc-052642	Lepisosteus oculatus	88.29	0.00e+00	3477.00
IUUC-Laf-053649	Loxodonta africana	96.22	0.00e+00	3744.00
IUUC-Mcc-055361	Macaca mulatta	97.90	0.00e+00	3380.00
IUUC-Meu-056618	Macropus eugenii	79.31	0.00e+00	1812.00
IUUC-Mga-059202	Meleagris gallopavo	93.25	0.00e+00	3582.00
IUUC-Mmr-060729	Microcebus murinus	95.81	0.00e+00	3823.00
IUUC-Mdo-062462	Monodelphis domestica	95.73	0.00e+00	3680.00
IUUC-Mmu-063865	Mus musculus	96.88	0.00e+00	3835.00
IUUC-Mpu-066724	Mustela putorius furo	99.54	0.00e+00	3895.00
IUUC-Mlu-067816	Myotis lucifugus	98.27	0.00e+00	3871.00
IUUC-Nle-069911	Nomascus leucogenys	74.89	0.00e+00	3088.00
IUUC-Opr-070213	Ochotona princeps	95.22	0.00e+00	2009.00
IUUC-Ont-071928	Oreochromis niloticus	79.89	0.00e+00	3256.00
IUUC-Oan-073563	Ornithorhynchus anatinus	95.47	0.00e+00	3771.00
IUUC-Ocu-074531	Oryctolagus cuniculus	98.37	0.00e+00	3864.00
IUUC-Ola-086943	Oryzias latipes	79.17	0.00e+00	3151.00
IUUC-Olu-087860	Ostreococcus lucimarinus	39.01	5.00e-118	418.00
IUUC-Oga-088665	Otolemur garnettii	97.00	0.00e+00	3707.00
IUUC-Oar-090429	Ovis aries	98.67	0.00e+00	3877.00
IUUC-Ptr-091168	Pan troglodytes	89.10	0.00e+00	3442.00
IUUC-Pan-092788	Papio anubis	97.76	0.00e+00	3064.00
IUUC-Psi-093281	Pelodiscus sinensis	92.57	0.00e+00	3658.00
IUUC-Pma-094424	Petromyzon marinus	72.83	9.00e-125	439.00
IUUC-Pfo-096073	Poecilia formosa	74.86	0.00e+00	3130.00
IUUC-Pab-098561	Pongo abelii	97.26	0.00e+00	3347.00
IUUC-Pca-100107	Procavia capensis	62.23	0.00e+00	1972.00
IUUC-Pva-102880	Pteropus vampyrus	71.75	0.00e+00	2820.00
IUUC-Rno-105002	Rattus norvegicus	96.07	0.00e+00	3817.00
IUUC-Sha-107105	Sarcophilus harrisii	93.10	0.00e+00	3559.00
IUUC-Sar-113401	Sorex araneus	69.10	0.00e+00	775.00
IUUC-Ssc-116282	Sus scrofa	98.73	0.00e+00	3771.00
IUUC-Tgu-116807	Taeniopygia guttata	94.13	0.00e+00	3687.00
IUUC-Tru-118040	Takifugu rubripes	79.39	0.00e+00	3191.00
IUUC-Tsy-118941	Tarsius syrichta	64.67	0.00e+00	2243.00
IUUC-Tni-120118	Tetraodon nigroviridis	76.75	0.00e+00	3158.00
IUUC-Tbe-127467	Tupaia belangeri	68.82	0.00e+00	1461.00
IUUC-Ttr-129138	Tursiops truncatus	71.32	0.00e+00	2811.00
IUUC-Vpa-130083	Vicugna pacos	71.10	0.00e+00	2724.00
IUUC-Xtr-131835	Xenopus tropicalis	73.90	0.00e+00	3105.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence