iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oan-073185

Ensembl Protein ID

ENSOANP00000001488.1

UniProt Accession

F6PIX0; F6PIX0_ORNAN

Protein Name

Uncharacterized protein

Gene Name

PHIP

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000000948.2	ENSOANT00000001489.1	ENSOANP00000001488.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.70e-35	118.1	139	176
UBD/Beta-Prp	3.10e-52	177.8	238	499

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gH +sv+c+ f  + +++ +GsdD+ +k+W +++g+ll
   Q: 139  GHLSSVYCVTFdRTgRRIFTGSDDCLVKIWATDDGRLL 176
           8**********955599*****************9987 PP

UBD/Beta-Prp

   S: 19   spdksllatgsrdgtikvwdvttgkl......lrslsgheaevtavk..fspdgkilvtgseDrtikvw..dlstgkcvhtlkghedsv 97
           s +k++l ++++dgti  w ++ g+l       +  +   ++v+ ++  fs  g +l+tgs+D++i+v+     +++ ++ l+ h d+v
   Q: 238  SGSKRYLSSTGADGTICFWLWDAGTLkinprpTKFTERPRPGVQMICssFSAGGMFLATGSTDHVIRVYffGSGQPEKISELEFHADKV 326
           67899***********999999999988888544447777777755522778888**************777779999*********** PP
   S: 98   lslsfspsgdklvsGshdrtirvwdletgqclee................tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgk 170
            s++fs +++++vsGs+d t+r+w+ + +++ +                  +++++  v++v+++  +n ++++ ++ t+++W++ tg+
   Q: 327  DSIQFSNTSNRFVSGSRDGTARIWQFKRREWKSIlldmatrpsgqtlqgiEDKITKLKVTMVAWDRHDNTVITAVNNMTLKVWNSYTGQ 415
           ********************************99***********99997777788889****************************** PP
   S: 171  llrtltgghtdsvysls...fdsngkelvsgsldgtvklwdlqtgecvrtlnght.....dnvksvrfspnderlvsgssDgsiriW 249
           l++ l g h+d v  l+   fd+  + l s+++dg v++wdl +g  +r++ +         v + + sp++++++++ s+g + i+
   Q: 416  LIHILMG-HEDEVFVLEphpFDP--RVLFSAGHDGNVIVWDLARGMKIRSYFNMIegqghGAVFDCKCSPDGQHFACTDSHGHLLIF 499
           ******9.*********999999..89********************9999875544455666667777999999999999988887 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

QLFPRRTDWT SKDHPRTYQN LVKYYRHLAP DHLLQICHRL GPLLEQEIPQ SVPGVQTLLG 60
AGRQSLLRTN KSCKHVVWKG SALAALHCGR PPESPVNYGS PPSIADTLFS RRLNGKYRLE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGCTGTTTC CCCGCCGCAC GGACTGGACG AGCAAGGACC ATCCCCGTAC CTACCAGAAC 60
CTGGTGAGCG CCCCCGCCCC CCCAAAAAAA CAAAAGGGGA GGGGGACCCA AAAACCACAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0103--Bromodomain
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR028738--PHIP
IPR027295--Quinoprotein_ADH-like_fam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00439--Bromodomain
PF00400--WD40

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM00320--WD40

Gene Ontology

GO:0005634--C:nucleus
GO:0007010--P:cytoskeleton organization
GO:0008286--P:insulin receptor signaling pathway
GO:0008360--P:regulation of cell shape
GO:0006357--P:regulation of transcription from RNA polymerase II promoter

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002299	Ailuropoda melanoleuca	87.51	0.00e+00	2921.00
IUUC-Atr-002600	Amborella trichopoda	33.00	7.00e-64	239.00
IUUC-Apl-003700	Anas platyrhynchos	85.35	0.00e+00	2819.00
IUUC-Aca-004474	Anolis carolinensis	81.39	0.00e+00	2722.00
IUUC-Bta-013125	Bos taurus	86.58	0.00e+00	2835.00
IUUC-Cja-018868	Callithrix jacchus	85.40	0.00e+00	2945.00
IUUC-Cfa-021179	Canis familiaris	86.50	0.00e+00	2833.00
IUUC-Cpo-022077	Cavia porcellus	81.31	0.00e+00	2792.00
IUUC-Csa-023618	Chlorocebus sabaeus	93.80	0.00e+00	1615.00
IUUC-Cho-024794	Choloepus hoffmanni	86.48	0.00e+00	840.00
IUUC-Dno-030048	Dasypus novemcinctus	87.08	0.00e+00	2894.00
IUUC-Dor-030195	Dipodomys ordii	85.99	0.00e+00	1401.00
IUUC-Eca-034274	Equus caballus	87.65	0.00e+00	2894.00
IUUC-Eeu-034688	Erinaceus europaeus	90.75	0.00e+00	1269.00
IUUC-Fca-035451	Felis catus	86.46	0.00e+00	2776.00
IUUC-Fal-037465	Ficedula albicollis	84.68	0.00e+00	2821.00
IUUC-Gmo-039451	Gadus morhua	67.98	0.00e+00	716.00
IUUC-Gga-040798	Gallus gallus	85.11	0.00e+00	2858.00
IUUC-Hsa-046757	Homo sapiens	93.80	0.00e+00	1597.00
IUUC-Hvu-047706	Hordeum vulgare	31.56	3.00e-37	148.00
IUUC-Itr-048843	Ictidomys tridecemlineatus	76.91	0.00e+00	951.00
IUUC-Lch-050646	Latimeria chalumnae	76.52	0.00e+00	2605.00
IUUC-Laf-054140	Loxodonta africana	87.50	0.00e+00	2937.00
IUUC-Mcc-055061	Macaca mulatta	94.17	0.00e+00	1621.00
IUUC-Mmr-060837	Microcebus murinus	87.14	0.00e+00	2913.00
IUUC-Mdo-061903	Monodelphis domestica	89.17	0.00e+00	3006.00
IUUC-Mmu-063772	Mus musculus	87.35	0.00e+00	2945.00
IUUC-Mpu-066359	Mustela putorius furo	87.20	0.00e+00	2667.00
IUUC-Mlu-067928	Myotis lucifugus	85.91	0.00e+00	2910.00
IUUC-Nle-070094	Nomascus leucogenys	93.92	0.00e+00	1602.00
IUUC-Opr-070971	Ochotona princeps	77.54	0.00e+00	756.00
IUUC-Ocu-074033	Oryctolagus cuniculus	87.12	0.00e+00	2680.00
IUUC-Ogl-077493	Oryza glaberrima	27.18	2.00e-30	128.00
IUUC-Ogu-078641	Oryza glumaepatula	29.19	5.00e-48	186.00
IUUC-Oin-079669	Oryza indica	31.43	5.00e-53	202.00
IUUC-Olo-080755	Oryza longistaminata	31.86	2.00e-55	211.00
IUUC-Oni-082991	Oryza nivara	24.07	2.00e-30	128.00
IUUC-Oga-088578	Otolemur garnettii	86.93	0.00e+00	2867.00
IUUC-Oar-090247	Ovis aries	86.80	0.00e+00	2835.00
IUUC-Ptr-091266	Pan troglodytes	93.43	0.00e+00	1579.00
IUUC-Pan-092734	Papio anubis	94.05	0.00e+00	1618.00
IUUC-Pfo-096191	Poecilia formosa	72.53	0.00e+00	2011.00
IUUC-Pab-098402	Pongo abelii	93.80	0.00e+00	1598.00
IUUC-Pca-101128	Procavia capensis	79.20	0.00e+00	2607.00
IUUC-Pva-103058	Pteropus vampyrus	92.12	0.00e+00	1360.00
IUUC-Rno-106013	Rattus norvegicus	86.54	0.00e+00	2881.00
IUUC-Sha-107496	Sarcophilus harrisii	89.07	0.00e+00	3010.00
IUUC-Sit-110017	Setaria italica	31.34	1.00e-55	211.00
IUUC-Sar-113520	Sorex araneus	78.97	0.00e+00	1309.00
IUUC-Ssc-115461	Sus scrofa	83.95	0.00e+00	2790.00
IUUC-Tgu-116821	Taeniopygia guttata	84.19	0.00e+00	2815.00
IUUC-Tsy-119132	Tarsius syrichta	75.92	0.00e+00	2321.00
IUUC-Tbe-127479	Tupaia belangeri	81.33	0.00e+00	1268.00
IUUC-Ttr-128427	Tursiops truncatus	83.56	0.00e+00	2758.00
IUUC-Vpa-130160	Vicugna pacos	84.26	0.00e+00	2766.00
IUUC-Xtr-132717	Xenopus tropicalis	74.07	0.00e+00	2490.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence