iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ppa-095416

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Predicted protein

Genbank Nucleotide ID

DS544894

Gene Name

PHYPADRAFT_174245

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
PP1S5_305V6	PP1S5_305V6.1	PP1S5_305V6.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	1.60e-170	568.5	454	940

Active Site

Position(s)	Description	Evidence
635	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv.....gsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvnve 91
           YD Qi+++G++ q+kl+++k +lvGag+lGcE+lKnL+l+Gv     g++tv+D+d +e+snl+rqFLfr++++g+ K+ va  a+  +np+ +++
   Q: 454  YDAQIAVFGSKLQQKLEESKLFLVGAGALGCEFLKNLALMGVscgpkGKLTVTDDDVIEKSNLSRQFLFRDWNIGQAKSTVASSAAIAINPSFRAV 549
           ************************************************************************************************ PP
   S: 92   aheesiteleeeiv...FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqktiPfctlketpnaae 184
           a ++++++ +e+++   F + +d+ v+aldn+ ar++++++c++ ++pl+esgtlG++ +++v+i+ lte y +s+dpp+k++P+ct+ ++p +++
   Q: 550  ALQNRVSPNTENVFddtFWEGLDLTVNALDNVNARLYIDSRCVYFQKPLLESGTLGTKCNTQVVIPNLTENYGASRDPPEKQAPMCTVHSFPHNID 645
           ************99999******************************************************************************* PP
   S: 185  htiewa............vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafakttinsikqllksfecdivtks 268
           h+++wa            + +n +l++ ++ ++  ++   ++ +e +++v + l++e+  +f+e+i++a+++f+ +++n +kql+  f+ d  t++
   Q: 646  HCLTWArsefegllektpAEANAFLSKPEEYKTAMKNAGDAQARELLERVVECLVTERCTTFDECIAWARTKFEDYFSNRVKQLTFTFPEDATTSN 741
           *****************999999************************************************************************* PP
   S: 269  kspfwv.........................................................sfcsna.ealqvpekvekdeevvkasap.lyll 305
           + pfw+                                                         +f + +  ++ ++ek+++  + + ++++ +++l
   Q: 742  GLPFWSapkrfpkhlqfsssdpsclsfvaaaailrastygisvpawaldakklaeavdkvkvsEFSPKQgVKIVTDEKATSLNASSMDDDYqIEML 837
           ********************************************9999888666666666555333222033334455555555444444499999 PP
   S: 306  lralerfekk..kgrkpgelsfekddds..avdlvtaaanlraeslgiepkldddlikeiagniipaiattnavvgGlaaqEviKvvsg.kfeplk 396
           +++l++  kk  +g k+  ++fekddd   ++dl++ +an+ra ++++++ +d+ + k iag+iipaiatt+a+  Gl+++E++Kv+ g   e ++
   Q: 838  IKTLDEGVKKlsPGFKMIPVTFEKDDDTnfHMDLIAGLANMRARNYSVPE-VDKLKAKFIAGRIIPAIATTTAMATGLVCLELYKVILGhNVERYR 932
           99998765543399************************************.************************************9978889** PP
   S: 397  nfflfdae 404
           n+f ++a+
   Q: 933  NTFANLAL 940
           ***99875 PP

Organism

Physcomitrella patens

Protein Sequence
(Fasta)

MLPKKREVGE EAELGSNSLK RNRAESPSGS VVVGRNRELV MAADSNMEVE IDEDLHSRQL 60
AVYGRETMRR LFGAHVLVSG LQGLGVEIAK NIILAGVKSV TLHDAGNVEL WDLSAQFYFT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTCTGAATAG TCAAGTGACG CTTCTCTTCA TTAGCGGAGG AAGCTGTGCG GCTGGTCCAC 60
GCCCCGATCT TTGTCGTTCG CATCGTCAGG TTTGTTTAGT CTTCCGTTTA CCCCATGTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0436--Ligase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR018074--UBQ-activ_enz_E1_CS
IPR033127--UBQ-activ_enz_E1_Cys_AS
IPR000011--UBQ/SUMO-activ_enz_E1-like

PROSITE

PS00536--UBIQUITIN_ACTIVAT_1
PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys

PRINTS

PR01849--UBIQUITINACT

SMART

SM00985--UBA_e1_C

Gene Ontology

GO:0005524--F:ATP binding
GO:0008641--F:small protein activating enzyme activity
GO:0006464--P:cellular protein modification process

KEGG

ppp:PHYPADRAFT_174245

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001311	Ailuropoda melanoleuca	45.82	0.00e+00	898.00
IUUC-Atr-002684	Amborella trichopoda	72.87	0.00e+00	1565.00
IUUC-Aca-004620	Anolis carolinensis	46.32	0.00e+00	895.00
IUUC-Ang-009737	Aspergillus niger	46.79	0.00e+00	840.00
IUUC-Bta-012767	Bos taurus	46.22	0.00e+00	908.00
IUUC-Cel-018260	Caenorhabditis elegans	39.32	0.00e+00	678.00
IUUC-Cja-019152	Callithrix jacchus	46.18	0.00e+00	907.00
IUUC-Cfa-020622	Canis familiaris	44.44	0.00e+00	857.00
IUUC-Cpo-022526	Cavia porcellus	46.55	0.00e+00	895.00
IUUC-Csa-023780	Chlorocebus sabaeus	46.24	0.00e+00	905.00
IUUC-Cme-027290	Cyanidioschyzon merolae	40.22	0.00e+00	694.00
IUUC-Dre-028149	Danio rerio	45.59	0.00e+00	883.00
IUUC-Dno-028884	Dasypus novemcinctus	46.08	0.00e+00	908.00
IUUC-Dor-030229	Dipodomys ordii	44.20	0.00e+00	855.00
IUUC-Dse-031524	Dothistroma septosporum	46.20	0.00e+00	819.00
IUUC-Ete-033124	Echinops telfairi	39.38	1.00e-131	463.00
IUUC-Eca-033330	Equus caballus	45.90	0.00e+00	895.00
IUUC-Eeu-035323	Erinaceus europaeus	39.97	3.00e-146	511.00
IUUC-Fca-036255	Felis catus	46.03	0.00e+00	902.00
IUUC-Fox-038007	Fusarium oxysporum	48.31	1.00e-137	482.00
IUUC-Ggr-039823	Gaeumannomyces graminis	46.93	0.00e+00	879.00
IUUC-Ggo-045336	Gorilla gorilla	46.24	0.00e+00	888.00
IUUC-Hsa-045982	Homo sapiens	46.24	0.00e+00	888.00
IUUC-Itr-048460	Ictidomys tridecemlineatus	46.19	0.00e+00	908.00
IUUC-Lch-050371	Latimeria chalumnae	46.36	0.00e+00	910.00
IUUC-Loc-052936	Lepisosteus oculatus	45.50	0.00e+00	897.00
IUUC-Laf-053948	Loxodonta africana	45.62	0.00e+00	880.00
IUUC-Mcc-055843	Macaca mulatta	46.15	0.00e+00	902.00
IUUC-Meu-056258	Macropus eugenii	46.65	0.00e+00	888.00
IUUC-Mor-057269	Magnaporthe oryzae	46.30	0.00e+00	866.00
IUUC-Mpo-057435	Magnaporthe poae	47.12	0.00e+00	867.00
IUUC-Mmr-061405	Microcebus murinus	45.50	0.00e+00	868.00
IUUC-Mdo-062032	Monodelphis domestica	44.72	0.00e+00	865.00
IUUC-Mmu-063280	Mus musculus	45.28	0.00e+00	882.00
IUUC-Mpu-066409	Mustela putorius furo	46.13	0.00e+00	914.00
IUUC-Mlu-067217	Myotis lucifugus	45.48	0.00e+00	889.00
IUUC-Nle-070072	Nomascus leucogenys	43.32	0.00e+00	810.00
IUUC-Oan-073268	Ornithorhynchus anatinus	39.02	8.00e-176	610.00
IUUC-Ogu-078305	Oryza glumaepatula	72.48	0.00e+00	1523.00
IUUC-Oin-080154	Oryza indica	72.77	0.00e+00	1524.00
IUUC-Olo-081089	Oryza longistaminata	72.87	0.00e+00	1528.00
IUUC-Oru-084469	Oryza rufipogon	72.77	0.00e+00	1526.00
IUUC-Olu-087687	Ostreococcus lucimarinus	60.87	0.00e+00	1188.00
IUUC-Oga-088594	Otolemur garnettii	46.15	0.00e+00	888.00
IUUC-Oar-090068	Ovis aries	45.85	0.00e+00	902.00
IUUC-Pan-092114	Papio anubis	46.15	0.00e+00	902.00
IUUC-Psi-093489	Pelodiscus sinensis	39.17	0.00e+00	677.00
IUUC-Pma-094214	Petromyzon marinus	48.84	2.00e-35	141.00
IUUC-Pab-097861	Pongo abelii	46.24	0.00e+00	875.00
IUUC-Pgr-103336	Puccinia graminis	45.58	0.00e+00	814.00
IUUC-Rno-105462	Rattus norvegicus	46.06	0.00e+00	882.00
IUUC-Sha-107142	Sarcophilus harrisii	45.67	0.00e+00	892.00
IUUC-Smo-109211	Selaginella moellendorffii	73.38	0.00e+00	1614.00
IUUC-Sar-113737	Sorex araneus	45.98	0.00e+00	902.00
IUUC-Ssc-115777	Sus scrofa	46.22	0.00e+00	902.00
IUUC-Tsy-119436	Tarsius syrichta	34.65	1.00e-153	536.00
IUUC-Tme-127055	Tuber melanosporum	44.99	0.00e+00	807.00
IUUC-Ttr-128331	Tursiops truncatus	46.18	0.00e+00	892.00
IUUC-Vpa-130716	Vicugna pacos	37.94	0.00e+00	634.00
IUUC-Xtr-132947	Xenopus tropicalis	36.50	7.00e-178	617.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence