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Tag Content
UUCD2 ID IUUC-Cpo-021293
UUCD1 version UUC-CaP-00262
Ensembl Protein ID ENSCPOP00000005101.2
UniProt Accession H0V5Z7; H0V5Z7_CAVPO
Genbank Protein ID ENSCPOP00000005101
Protein Name Uncharacterized protein
Genbank Nucleotide ID AAKN02049458
Gene Name CUL3
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSCPOG00000005658.3 ENSCPOT00000005719.2 ENSCPOP00000005101.2
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/Cullin 1.70e-230 766.9 37 665
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/Cullin
   S: 2    lreavkkilrqesvkkeyeelytavynlclskvgaklYkklkevleefi.kqvkkkveesedeqlLktynreWekfreqlkvlrkifay 89
           l++a+++i+r++++  ++eely+++y+++l+k+g+klY+ l+ev++e++ ++v+++v +s ++++L+t+n++W++++++++++r+i++y
   Q: 37   LKNAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGEKLYTGLREVVTEHLiNKVREDVLNSLNNNFLQTLNQAWNDHQTAMVMIRDILMY 125
           799*********************************************99*************************************** PP
   S: 90   ldrtyvkkskkvsevrkLaldlwrkeived..ikkrllelllklieaeRkgeavdrrllsgvveslveLslnklaiykesFEakfleat 176
           +dr+yv++ ++v++v++L+l ++r+++v++  i+++l ++ll++i++eRkge+vdr  +++++++l+ L+l+ +++y+e+FEa+fle++
   Q: 126  MDRVYVQQ-NNVENVYNLGLIIFRDQVVRYgcIRDHLRQTLLDMIARERKGEVVDRGAIRNACQMLMILGLEGRTVYEEDFEAPFLEMS 213
           ********.******************************************************************************** PP
   S: 177  qefykaesaeflqenevdeYlkkvearlneeeeraaryleestetkLlevvekeliakhlesll....aelvallrdkktedlsrmykL 261
           +ef+++es++fl+en+ + Y+kkvear+nee er++++l++ste+++++vve+eli+kh+++++    ++lv++l++ ktedl++mykL
   Q: 214  AEFFQMESQKFLAENSASVYIKKVEARINEEIERVMHCLDKSTEEPIVKVVERELISKHMKTIVemenSGLVHMLKNGKTEDLACMYKL 302
           ****************************************************************99999******************** PP
   S: 262  lsrvlngleellkeleshikeqgkaaltaeekekdpkkyVerllelknklqklvseaFnndakFlkaldkafetfvnknsvlkaakspE 350
           +srv+ngl++++++++s+++eqgka++++e + k+p++y++ ll+lk++++++++e+Fnnd+ F ++++ +fe+f+n n     ++spE
   Q: 303  FSRVPNGLKTMCECMSSYLREQGKALVSEEGEGKNPVDYIQGLLDLKSRFDRFLQESFNNDRLFKQTIAGDFEYFLNLN-----SRSPE 386
           *******************************************************************************.....***** PP
   S: 351  llAryiDqlLrksskglteeeleaqldkvllvfkyisekdvFekyYkkhLakRLlsgksasseaEesviekLkeecgaeftskLerMfq 439
           +l+ +iD++L+k++kglte+e+e++ldk++++f++++ekdvFe+yYk+hLa+RLl++ks+s+++E+++i+kLk+ecg++ftskLe+Mf+
   Q: 387  YLSLFIDDKLKKGVKGLTEQEVETILDKAMVLFRFMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFR 475
           ***************************************************************************************** PP
   S: 440  dlkvSedlnrqFkeekentees.esvelsvlvLsagaWptasetekvsLPaelektiekfeefYlekhsgRkLqWqhtlgraelkael. 526
           d+++S++++++F+++ ++t  s  +v+l+v+vL++g+Wpt+s+t+k+++P+  ++++e+f++fYl khsgR+L++qh++g+a+l+a++ 
   Q: 476  DMSISNTTMDEFRQHLQATGVSlGGVDLTVRVLTTGYWPTQSATPKCNIPPAPRHAFEIFRRFYLAKHSGRQLTLQHHMGSADLNATFy 564
           ********************99889**************************************************************** PP
   S: 527  .....................kkgkyelqVstfQmavLLafnnsekvsveelkkatelpeeeLrrtlqsLvssk..kqvlkkepeskei 592
                                +++k++lqVstfQm++L++fnn+ek+++ee++++t++pe+eL r+lqsL+++k  ++vl+kep+skei
   Q: 565  gpvkkedgsevgvggaqvtgsNTRKHILQVSTFQMTILMLFNNREKYTFEEIQQETDIPERELVRALQSLACGKptQRVLTKEPKSKEI 653
           *********999999998888888***************************************************************** PP
   S: 593  eeedlfsvNqef 604
           e++++f+vN++f
   Q: 654  ENGHIFTVNDQF 665
           **********99 PP
   
Organism Cavia porcellus
Protein Sequence
(Fasta)
KSCICKNEGI LKRLRINVRR FSMTMDEKYV NSIWDLLKNA IQEIQRKNNS GLSFEELYRN 60
AYTMVLHKHG EKLYTGLREV VTEHLINKVR EDVLNSLNNN FLQTLNQAWN DHQTAMVMIR 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Cpo-021293|E3,Cullin|Cavia porcellus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AAGAGTTGTA TCTGTAAGAA TGAGGGGATC TTAAAAAGAT TAAAAAAGTT GTTTTTAATT 60
GCACATGTAT ATTTTTACTT CTATTAAATG TATACTTTTT ACTTCTATTA AAACAGGTTA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Cpo-021293|E3,Cullin|Cavia porcellus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
Interpro

IPR016157--Cullin_CS
IPR016158--Cullin_homology
IPR001373--Cullin_N
IPR019559--Cullin_neddylation_domain
IPR016159--Cullin_repeat-like_dom
IPR011991--WHTH_DNA-bd_dom
PROSITE

PS01256--CULLIN_1
PS50069--CULLIN_2
Pfam

PF00888--Cullin
PF10557--Cullin_Nedd8
SMART

SM00182--CULLIN
SM00884--Cullin_Nedd8
Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0070062--C:extracellular exosome
GO:0000139--C:Golgi membrane
GO:0005634--C:nucleus
GO:0005827--C:polar microtubule
GO:0004842--F:ubiquitin-protein transferase activity
GO:0031145--P:anaphase-promoting complex-dependent catabolic process
GO:0016477--P:cell migration
GO:0048208--P:COPII vesicle coating
GO:0040016--P:embryonic cleavage
GO:0044346--P:fibroblast apoptotic process
GO:0007369--P:gastrulation
GO:0007229--P:integrin-mediated signaling pathway
GO:0072576--P:liver morphogenesis
GO:0007080--P:mitotic metaphase plate congression
GO:0035024--P:negative regulation of Rho protein signal transduction
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0032467--P:positive regulation of cytokinesis
GO:0045842--P:positive regulation of mitotic metaphase/anaphase transition
GO:0006513--P:protein monoubiquitination
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0017145--P:stem cell division
GO:0043149--P:stress fiber assembly
GO:0001831--P:trophectodermal cellular morphogenesis
GO:0071630--P:ubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome
GO:0016055--P:Wnt signaling pathway
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000335 Aegilops tauschii 46.95 0.00e+00 685.00
IUUC-Aml-002278 Ailuropoda melanoleuca 97.15 0.00e+00 1521.00
IUUC-Atr-002616 Amborella trichopoda 52.70 0.00e+00 773.00
IUUC-Apl-004172 Anas platyrhynchos 99.73 0.00e+00 1518.00
IUUC-Aca-004309 Anolis carolinensis 97.78 0.00e+00 1528.00
IUUC-Aly-005566 Arabidopsis lyrata 51.45 0.00e+00 767.00
IUUC-Ath-007587 Arabidopsis thaliana 51.85 0.00e+00 773.00
IUUC-Ago-007795 Ashbya gossypii 25.13 2.00e-48 187.00
IUUC-Acl-008317 Aspergillus clavatus 36.87 5.00e-145 508.00
IUUC-Afl-008727 Aspergillus flavus 36.53 8.00e-145 508.00
IUUC-Afu-008879 Aspergillus fumigatus 37.96 1.00e-132 467.00
IUUC-Ani-009393 Aspergillus nidulans 35.99 2.00e-135 476.00
IUUC-Ang-009626 Aspergillus niger 36.44 3.00e-141 496.00
IUUC-Aor-010207 Aspergillus oryzae 36.53 2.00e-144 506.00
IUUC-Ate-010305 Aspergillus terreus 37.16 1.00e-140 493.00
IUUC-Ame-011805 Astyanax mexicanus 96.05 0.00e+00 1492.00
IUUC-Bgr-012098 Blumeria graminis 36.02 8.00e-121 427.00
IUUC-Bta-013445 Bos taurus 97.91 0.00e+00 1531.00
IUUC-Bci-013612 Botrytis cinerea 36.61 4.00e-139 488.00
IUUC-Bdi-014269 Brachypodium distachyon 52.51 0.00e+00 746.00
IUUC-Bol-015350 Brassica oleracea 51.98 0.00e+00 770.00
IUUC-Bra-016763 Brassica rapa 52.11 0.00e+00 773.00
IUUC-Cel-018641 Caenorhabditis elegans 48.57 0.00e+00 723.00
IUUC-Cja-019175 Callithrix jacchus 97.78 0.00e+00 1527.00
IUUC-Cfa-020905 Canis familiaris 99.47 0.00e+00 1521.00
IUUC-Cre-022776 Chlamydomonas reinhardtii 48.29 0.00e+00 697.00
IUUC-Csa-023800 Chlorocebus sabaeus 97.65 0.00e+00 1525.00
IUUC-Cho-024839 Choloepus hoffmanni 98.82 0.00e+00 1353.00
IUUC-Cin-025201 Ciona intestinalis 70.90 0.00e+00 1008.00
IUUC-Csv-026107 Ciona savignyi 71.33 0.00e+00 1094.00
IUUC-Cgl-026630 Colletotrichum gloeosporioides 35.43 1.00e-124 440.00
IUUC-Cne-027048 Cryptococcus neoformans 34.80 3.00e-117 416.00
IUUC-Cme-027254 Cyanidioschyzon merolae 31.09 4.00e-88 318.00
IUUC-Dre-028488 Danio rerio 96.45 0.00e+00 1500.00
IUUC-Dno-029784 Dasypus novemcinctus 98.04 0.00e+00 1529.00
IUUC-Dor-030682 Dipodomys ordii 92.49 0.00e+00 1367.00
IUUC-Dse-031326 Dothistroma septosporum 35.74 2.00e-128 452.00
IUUC-Dme-032112 Drosophila melanogaster 69.57 0.00e+00 1082.00
IUUC-Ete-032347 Echinops telfairi 82.86 0.00e+00 1195.00
IUUC-Eca-033560 Equus caballus 99.73 0.00e+00 1520.00
IUUC-Eeu-034502 Erinaceus europaeus 97.79 0.00e+00 1343.00
IUUC-Fca-035544 Felis catus 99.87 0.00e+00 1521.00
IUUC-Fal-036751 Ficedula albicollis 99.47 0.00e+00 1520.00
IUUC-Fox-037857 Fusarium oxysporum 36.92 2.00e-137 483.00
IUUC-Fso-038163 Fusarium solani 36.75 5.00e-141 494.00
IUUC-Gmo-039270 Gadus morhua 95.95 0.00e+00 1501.00
IUUC-Ggr-039999 Gaeumannomyces graminis 33.45 2.00e-128 453.00
IUUC-Gga-040329 Gallus gallus 97.78 0.00e+00 1529.00
IUUC-Gac-041510 Gasterosteus aculeatus 95.82 0.00e+00 1496.00
IUUC-Gma-043182 Glycine max 52.15 0.00e+00 747.00
IUUC-Ggo-044903 Gorilla gorilla 99.46 0.00e+00 1511.00
IUUC-Hsa-046000 Homo sapiens 97.65 0.00e+00 1525.00
IUUC-Hvu-047831 Hordeum vulgare 52.46 0.00e+00 700.00
IUUC-Itr-049067 Ictidomys tridecemlineatus 100.00 0.00e+00 942.00
IUUC-Kpa-049372 Komagataella pastoris 35.07 2.00e-115 409.00
IUUC-Lch-050458 Latimeria chalumnae 99.06 0.00e+00 1515.00
IUUC-Lpe-051396 Leersia perrieri 51.98 0.00e+00 758.00
IUUC-Loc-052186 Lepisosteus oculatus 97.76 0.00e+00 1522.00
IUUC-Lma-053030 Leptosphaeria maculans 38.15 3.00e-144 506.00
IUUC-Laf-053684 Loxodonta africana 99.87 0.00e+00 1521.00
IUUC-Mcc-055770 Macaca mulatta 97.65 0.00e+00 1525.00
IUUC-Meu-056852 Macropus eugenii 100.00 0.00e+00 763.00
IUUC-Mor-057273 Magnaporthe oryzae 34.76 4.00e-133 468.00
IUUC-Mpo-057403 Magnaporthe poae 34.00 1.00e-129 457.00
IUUC-Mtr-058317 Medicago truncatula 51.85 0.00e+00 754.00
IUUC-Mla-059055 Melampsora laricipopulina 37.28 6.00e-133 468.00
IUUC-Mga-060076 Meleagris gallopavo 98.12 0.00e+00 1488.00
IUUC-Mvi-060470 Microbotryum violaceum 33.52 3.00e-135 476.00
IUUC-Mmr-060976 Microcebus murinus 97.91 0.00e+00 1531.00
IUUC-Mdo-062741 Monodelphis domestica 97.91 0.00e+00 1531.00
IUUC-Mmu-063905 Mus musculus 97.65 0.00e+00 1526.00
IUUC-Mac-064718 Musa acuminata 50.59 0.00e+00 729.00
IUUC-Mpu-066356 Mustela putorius furo 99.87 0.00e+00 1521.00
IUUC-Mlu-067768 Myotis lucifugus 99.33 0.00e+00 1515.00
IUUC-Nfi-068285 Neosartorya fischeri 37.20 2.00e-146 512.00
IUUC-Ncr-068883 Neurospora crassa 36.31 2.00e-138 486.00
IUUC-Nle-069638 Nomascus leucogenys 99.33 0.00e+00 1516.00
IUUC-Opr-070333 Ochotona princeps 90.75 0.00e+00 1268.00
IUUC-Ont-071601 Oreochromis niloticus 96.97 0.00e+00 1544.00
IUUC-Oan-073281 Ornithorhynchus anatinus 99.68 0.00e+00 1302.00
IUUC-Ocu-074504 Oryctolagus cuniculus 97.65 0.00e+00 1524.00
IUUC-Oba-075332 Oryza barthii 52.26 0.00e+00 749.00
IUUC-Obr-076435 Oryza brachyantha 53.12 0.00e+00 714.00
IUUC-Ogl-077655 Oryza glaberrima 52.24 0.00e+00 758.00
IUUC-Ogu-078458 Oryza glumaepatula 52.26 0.00e+00 749.00
IUUC-Oin-079567 Oryza indica 52.11 0.00e+00 756.00
IUUC-Olo-080930 Oryza longistaminata 53.02 0.00e+00 757.00
IUUC-Ome-081353 Oryza meridionalis 52.24 0.00e+00 757.00
IUUC-Oni-082378 Oryza nivara 52.24 0.00e+00 758.00
IUUC-Opu-084055 Oryza punctata 52.24 0.00e+00 759.00
IUUC-Oru-084202 Oryza rufipogon 52.26 0.00e+00 749.00
IUUC-Osa-085290 Oryza sativa 52.24 0.00e+00 758.00
IUUC-Ola-087562 Oryzias latipes 96.71 0.00e+00 1507.00
IUUC-Olu-087866 Ostreococcus lucimarinus 37.66 3.00e-139 489.00
IUUC-Oga-088833 Otolemur garnettii 99.87 0.00e+00 1521.00
IUUC-Oar-089958 Ovis aries 99.87 0.00e+00 1521.00
IUUC-Ptr-091013 Pan troglodytes 97.65 0.00e+00 1525.00
IUUC-Pan-091796 Papio anubis 98.93 0.00e+00 1505.00
IUUC-Psi-093564 Pelodiscus sinensis 98.12 0.00e+00 1486.00
IUUC-Pno-094939 Phaeosphaeria nodorum 37.74 2.00e-138 486.00
IUUC-Ppa-095920 Physcomitrella patens 51.83 0.00e+00 767.00
IUUC-Pfo-097498 Poecilia formosa 92.57 0.00e+00 1491.00
IUUC-Pab-098164 Pongo abelii 97.65 0.00e+00 1525.00
IUUC-Pop-099497 Populus trichocarpa 53.03 0.00e+00 786.00
IUUC-Pca-100702 Procavia capensis 89.70 0.00e+00 1357.00
IUUC-Ppe-101271 Prunus persica 52.11 0.00e+00 743.00
IUUC-Pva-103129 Pteropus vampyrus 97.78 0.00e+00 1530.00
IUUC-Pgr-103684 Puccinia graminis 36.30 6.00e-110 392.00
IUUC-Ptt-103961 Puccinia triticina 36.48 5.00e-109 389.00
IUUC-Pte-104325 Pyrenophora teres 38.06 2.00e-135 476.00
IUUC-Pyt-104746 Pyrenophora triticirepentis 37.09 1.00e-133 470.00
IUUC-Rno-105935 Rattus norvegicus 99.73 0.00e+00 1518.00
IUUC-Sce-106354 Saccharomyces cerevisiae 26.52 4.00e-53 202.00
IUUC-Sha-106569 Sarcophilus harrisii 99.27 0.00e+00 1383.00
IUUC-Sja-107676 Schizosaccharomyces japonicus 38.87 2.00e-154 539.00
IUUC-Spo-108135 Schizosaccharomyces pombe 38.04 2.00e-138 486.00
IUUC-Smo-109555 Selaginella moellendorffii 53.49 0.00e+00 789.00
IUUC-Sit-110763 Setaria italica 52.90 0.00e+00 761.00
IUUC-Sly-111090 Solanum lycopersicum 51.72 0.00e+00 764.00
IUUC-Stu-112351 Solanum tuberosum 51.85 0.00e+00 766.00
IUUC-Sar-113144 Sorex araneus 99.82 0.00e+00 1118.00
IUUC-Sbi-114690 Sorghum bicolor 52.11 0.00e+00 760.00
IUUC-Sre-115005 Sporisorium reilianum 37.90 5.00e-135 475.00
IUUC-Ssc-116053 Sus scrofa 99.82 0.00e+00 1143.00
IUUC-Tgu-116523 Taeniopygia guttata 99.87 0.00e+00 1521.00
IUUC-Tru-118189 Takifugu rubripes 92.76 0.00e+00 1413.00
IUUC-Tsy-118962 Tarsius syrichta 93.67 0.00e+00 1388.00
IUUC-Tni-120614 Tetraodon nigroviridis 57.20 0.00e+00 875.00
IUUC-Tca-121282 Theobroma cacao 52.50 0.00e+00 767.00
IUUC-Tre-122201 Trichoderma reesei 35.88 5.00e-134 471.00
IUUC-Tvi-122321 Trichoderma virens 36.29 2.00e-134 473.00
IUUC-Tae-124292 Triticum aestivum 51.85 0.00e+00 741.00
IUUC-Tur-126800 Triticum urartu 51.72 0.00e+00 739.00
IUUC-Tme-127053 Tuber melanosporum 39.90 7.00e-157 547.00
IUUC-Tbe-127427 Tupaia belangeri 85.06 0.00e+00 1162.00
IUUC-Ttr-128662 Tursiops truncatus 97.99 0.00e+00 1481.00
IUUC-Uma-129597 Ustilago maydis 38.40 2.00e-134 473.00
IUUC-Vda-129726 Verticillium dahliae 35.32 6.00e-134 471.00
IUUC-Vpa-130809 Vicugna pacos 99.73 0.00e+00 744.00
IUUC-Vvi-131194 Vitis vinifera 52.74 0.00e+00 760.00
IUUC-Xtr-131887 Xenopus tropicalis 96.88 0.00e+00 1515.00
IUUC-Xma-133517 Xiphophorus maculatus 96.84 0.00e+00 1511.00
IUUC-Yli-134576 Yarrowia lipolytica 33.33 8.00e-111 394.00
IUUC-Zma-135030 Zea mays 52.51 0.00e+00 767.00
Created Date 25-Jun-2017

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