iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062172

UUCD1 version

UUC-MoD-01140

Ensembl Protein ID

ENSMODP00000010378.2

UniProt Accession

F7EKN3; F7EKN3_MONDO

Protein Name

Uncharacterized protein

Gene Name

USP43

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000008348.3	ENSMODT00000010579.3	ENSMODP00000010378.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.50e-75	254.6	219	689

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 138  nkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke......................................... 185
           ++s++++ Fq q++s+++c++c+++s++++pfl +slp+p+ ++++++                                         
   Q: 219  GQSFVQNHFQAQYRSSLTCPHCQKQSNTFDPFLCVSLPIPSCQTRSLNvtlvfqsksqmflriglavplfstvatlrkmiaeegkisan 307
           679****************************************99888***************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 308  evvlvelhpsgfqrsffdeedlncisdgdnvyafqaplspiwgvpasfsgivvpstlstesltsgsgskvlillcnlvgsghkakrfgp 396
           ***************************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 397  pllmredraiswdqfqqqvfstiqclmkkevslqslgslfavrvvglsnvcsylspqdgrplfhwaverslklsrpggpphiklaiewd 485
           ***************************************************************************************** PP
   S: 186  ..................................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfs 240
                                             +l++c++ +tkee+l  +++++c++ck +q+   kl+l++lP++Li+hLkRf   
   Q: 486  kttkelffgniqeevvqdapsvqlqqqahlqpscTLNECFQLYTKEEQLAPDDAWKCPHCKILQQGMVKLSLWTLPDILIIHLKRF--C 572
           **************************************************************************************..8 PP
   S: 241  eeqksrekinkkvefple.Ldlspfctspeekqke....................kkkYeLiavvvHsGslssGHYvayvkn.ekgkWl 307
           + +++r+k+++ v+fpl  L+++p++++++ +q++                    +  Y+L+av++H+Gs+++GHY+ay++n  +g+W+
   Q: 573  QVGERRNKLSTLVKFPLFgLNMAPHVAKRSLGQEHlmnswpsweqasclpnncsfDFLYDLYAVCNHHGSMQGGHYTAYCRNsLDGQWY 661
           8899************************888887799999999999999999999***************************55788** PP
   S: 308  lfdDskVtevkeeevleetgstaYvlfYkrr 338
            +dDs+V++v+eeev +   + aY+lfY++r
   Q: 662  SYDDSTVEPVSEEEVST---RGAYILFYQKR 689
           *****************...********985 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

GGPSAPPRRR RSFRRLLGRF LRVLGVLPSS GVSSPETQPG VNQSGTGRGS NSSEGFGDSA 60
RSANEVSREA GVARLPQPPP GDKARPPGTQ GLKNHGNTCF MNAVVQCLSN TDLLAEFLAL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGGGGCCAT CCGCTCCACC CCGTCGCCGC CGCTCCTTTC GCCGTCTTCT CGGCCGCTTT 60
CTCCGAGTTC TGGGCGTCCT CCCCAGCTCT GGGGTCTCCT CACCGGAGAC CCAACCTGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0732--Signal

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005634--C:nucleus
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001922	Ailuropoda melanoleuca	61.99	0.00e+00	865.00
IUUC-Aca-004436	Anolis carolinensis	63.07	0.00e+00	757.00
IUUC-Ame-011153	Astyanax mexicanus	52.20	0.00e+00	812.00
IUUC-Bta-013560	Bos taurus	66.93	0.00e+00	972.00
IUUC-Cja-018737	Callithrix jacchus	66.19	0.00e+00	990.00
IUUC-Cfa-020347	Canis familiaris	65.66	0.00e+00	937.00
IUUC-Csa-023656	Chlorocebus sabaeus	66.97	0.00e+00	989.00
IUUC-Cho-024864	Choloepus hoffmanni	54.52	0.00e+00	662.00
IUUC-Dre-028066	Danio rerio	55.68	0.00e+00	820.00
IUUC-Dno-028855	Dasypus novemcinctus	64.65	0.00e+00	941.00
IUUC-Dor-030475	Dipodomys ordii	72.01	2.00e-169	590.00
IUUC-Dme-032088	Drosophila melanogaster	34.77	2.00e-94	340.00
IUUC-Eca-034147	Equus caballus	66.28	0.00e+00	955.00
IUUC-Eeu-034703	Erinaceus europaeus	69.13	7.00e-90	325.00
IUUC-Fca-036550	Felis catus	64.39	0.00e+00	780.00
IUUC-Gac-042087	Gasterosteus aculeatus	56.59	0.00e+00	756.00
IUUC-Ggo-045171	Gorilla gorilla	66.93	0.00e+00	988.00
IUUC-Hsa-045961	Homo sapiens	66.93	0.00e+00	992.00
IUUC-Loc-052852	Lepisosteus oculatus	57.78	0.00e+00	832.00
IUUC-Laf-054033	Loxodonta africana	67.59	0.00e+00	948.00
IUUC-Mcc-055431	Macaca mulatta	66.93	0.00e+00	991.00
IUUC-Meu-056444	Macropus eugenii	84.05	2.00e-148	520.00
IUUC-Mmr-061035	Microcebus murinus	67.01	0.00e+00	964.00
IUUC-Mmu-063966	Mus musculus	66.62	0.00e+00	975.00
IUUC-Mpu-066307	Mustela putorius furo	65.19	0.00e+00	879.00
IUUC-Nle-070172	Nomascus leucogenys	67.18	0.00e+00	993.00
IUUC-Opr-070499	Ochotona princeps	62.13	0.00e+00	900.00
IUUC-Ont-071920	Oreochromis niloticus	57.61	0.00e+00	818.00
IUUC-Ocu-074014	Oryctolagus cuniculus	65.45	0.00e+00	859.00
IUUC-Ola-086360	Oryzias latipes	57.29	0.00e+00	800.00
IUUC-Oga-088202	Otolemur garnettii	65.38	0.00e+00	950.00
IUUC-Oar-089819	Ovis aries	65.06	0.00e+00	896.00
IUUC-Ptr-091076	Pan troglodytes	67.18	0.00e+00	996.00
IUUC-Pan-092248	Papio anubis	66.93	0.00e+00	989.00
IUUC-Pfo-096332	Poecilia formosa	54.56	0.00e+00	791.00
IUUC-Pab-098453	Pongo abelii	64.56	0.00e+00	941.00
IUUC-Pca-100290	Procavia capensis	56.42	4.00e-123	435.00
IUUC-Pva-102317	Pteropus vampyrus	57.88	0.00e+00	777.00
IUUC-Rno-104948	Rattus norvegicus	64.25	0.00e+00	868.00
IUUC-Sha-106558	Sarcophilus harrisii	76.70	0.00e+00	1237.00
IUUC-Sar-113105	Sorex araneus	57.54	0.00e+00	713.00
IUUC-Ssc-115312	Sus scrofa	66.28	0.00e+00	963.00
IUUC-Tru-117995	Takifugu rubripes	58.56	0.00e+00	823.00
IUUC-Tsy-119325	Tarsius syrichta	57.23	3.00e-145	509.00
IUUC-Tni-120517	Tetraodon nigroviridis	54.09	0.00e+00	761.00
IUUC-Tbe-127439	Tupaia belangeri	58.46	2.00e-45	177.00
IUUC-Ttr-128829	Tursiops truncatus	65.42	3.00e-173	602.00
IUUC-Vpa-130306	Vicugna pacos	57.39	4.00e-116	412.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence