iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ssc-116424

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

CU459172

Gene Name

CBLC

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000003083.1	ENSSSCT00000003421.1	ENSSSCP00000003338.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	2.70e-06	28.1	354	393

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C iC e+ kd +++ pCgH+ +  Cl  w     + s +++CP Cr
   Q: 354  CKICAERNKD-VKIEPCGHLLCSRCLATW-----QNSDSQTCPFCR 393
           99********.******************.....7899999****8 PP

Organism

Sus scrofa

Protein Sequence
(Fasta)

PMAAAARRGP QWGESRAFGR AVRLLQRLGE QCRDPRLGSG PPSLRDLLPR TAQLLREVAQ 60
ARRAAGGGGP EAAEGPGGAG DFLMVFLANL EAKSRQVAAL LPPRGRKTAA DELFREGSRL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCATGGCTG CGGCGGCCCG GCGGGGACCG CAGTGGGGAG AATCCCGCGC GTTCGGCCGG 60
GCGGTGAGGC TGCTGCAGCG CCTAGGAGAG CAATGCAGGG ACCCCCGACT CGGCTCCGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR024162--Adaptor_Cbl
IPR014741--Adaptor_Cbl_EF_hand-like
IPR003153--Adaptor_Cbl_N_hlx
IPR014742--Adaptor_Cbl_SH2-like
IPR024159--Cbl_PTB
IPR011992--EF-hand-dom_pair
IPR000980--SH2
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51506--CBL_PTB
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF02262--Cbl_N
PF02761--Cbl_N2
PF02762--Cbl_N3

SMART

SM00184--RING

Gene Ontology

GO:0045121--C:membrane raft
GO:0005634--C:nucleus
GO:0005886--C:plasma membrane
GO:0005509--F:calcium ion binding
GO:0030971--F:receptor tyrosine kinase binding
GO:0017124--F:SH3 domain binding
GO:0004871--F:signal transducer activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0007173--P:epidermal growth factor receptor signaling pathway
GO:0007175--P:negative regulation of epidermal growth factor-activated receptor activity
GO:0006508--P:proteolysis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002286	Ailuropoda melanoleuca	80.04	0.00e+00	713.00
IUUC-Bta-012705	Bos taurus	83.43	0.00e+00	755.00
IUUC-Cja-019179	Callithrix jacchus	80.60	0.00e+00	689.00
IUUC-Cfa-020593	Canis familiaris	78.06	0.00e+00	703.00
IUUC-Cpo-021289	Cavia porcellus	74.76	6.00e-173	600.00
IUUC-Csa-023966	Chlorocebus sabaeus	75.40	0.00e+00	651.00
IUUC-Dor-030246	Dipodomys ordii	77.12	1.00e-125	442.00
IUUC-Eca-033921	Equus caballus	72.58	6.00e-155	540.00
IUUC-Fca-035747	Felis catus	66.34	4.00e-173	600.00
IUUC-Ggo-044622	Gorilla gorilla	85.08	1.00e-160	558.00
IUUC-Hsa-045735	Homo sapiens	82.18	0.00e+00	694.00
IUUC-Itr-049001	Ictidomys tridecemlineatus	78.81	0.00e+00	634.00
IUUC-Laf-053983	Loxodonta africana	77.34	0.00e+00	702.00
IUUC-Mmr-061310	Microcebus murinus	75.88	0.00e+00	668.00
IUUC-Mmu-064155	Mus musculus	71.31	0.00e+00	681.00
IUUC-Mpu-066655	Mustela putorius furo	75.97	0.00e+00	687.00
IUUC-Mlu-067929	Myotis lucifugus	85.76	2.00e-156	544.00
IUUC-Nle-070065	Nomascus leucogenys	68.29	9.00e-158	549.00
IUUC-Ocu-074049	Oryctolagus cuniculus	66.93	8.00e-132	462.00
IUUC-Opu-083619	Oryza punctata	43.14	7.00e-08	50.40
IUUC-Oga-087952	Otolemur garnettii	82.69	0.00e+00	728.00
IUUC-Oar-089382	Ovis aries	80.64	0.00e+00	699.00
IUUC-Pan-092075	Papio anubis	80.37	0.00e+00	646.00
IUUC-Pab-098100	Pongo abelii	73.15	4.00e-171	593.00
IUUC-Pca-100830	Procavia capensis	76.47	1.00e-107	382.00
IUUC-Pva-102714	Pteropus vampyrus	77.84	4.00e-165	573.00
IUUC-Rno-105348	Rattus norvegicus	72.51	0.00e+00	676.00
IUUC-Sha-107138	Sarcophilus harrisii	65.06	3.00e-124	437.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence