iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ptr-090592

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AACZ03080821

Gene Name

UBE4A

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000004341.4	ENSPTRT00000008065.4	ENSPTRP00000007445.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	3.00e-22	78.4	995	1066

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 2    vpeeflCpIslelMrdPvvlp.sGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawceens 73
            ++efl+pI+ +lM+dPvvlp s++t+drs+I+++l s+++ +P++r+plt +++ Pn++l++ iq+w++e++
   Q: 995  ACDEFLDPIMSTLMCDPVVLPsSRVTVDRSTIARHLLSDQT-DPFNRSPLTMDQIRPNTELKEKIQRWLAERK 1066
           579******************9******************9.***************************9976 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MTDQENNNNI SSNPFAALFG SLADAKQFAA IQKEQLKQQS DELPASPDDS DNSVSESLDE 60
FDYSVAEISR SFRSQQEICE QLNINHMIQR IFLITLDNSD PSLKSGNGIP SRCVYLEEMA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GACGTAACTT CCGGTTGCTG TGCTGAGTCG GAAGTGAGAG CCTTTCGGCC GCTGAGTTTC 60
TGTCGTGTCG TCGCTGCTGG CACTTCAGGC TCTGGTAAGG CAGGCAATAG CTTCAGGGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011989--ARM-like
IPR019474--Ub_conjug_fac_E4_core
IPR003613--Ubox_domain
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51698--U_BOX

Pfam

PF04564--U-box
PF10408--Ufd2P_core

SMART

SM00504--Ubox

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0000151--C:ubiquitin ligase complex
GO:0034450--F:ubiquitin-ubiquitin ligase activity
GO:0000209--P:protein polyubiquitination
GO:0030433--P:ubiquitin-dependent ERAD pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001281	Ailuropoda melanoleuca	98.60	0.00e+00	2105.00
IUUC-Apl-003514	Anas platyrhynchos	88.61	0.00e+00	1887.00
IUUC-Aca-005167	Anolis carolinensis	85.43	0.00e+00	1757.00
IUUC-Ame-010905	Astyanax mexicanus	66.89	0.00e+00	704.00
IUUC-Bta-012413	Bos taurus	96.09	0.00e+00	2078.00
IUUC-Cja-019715	Callithrix jacchus	99.35	0.00e+00	2152.00
IUUC-Cfa-021185	Canis familiaris	97.86	0.00e+00	2139.00
IUUC-Cpo-021516	Cavia porcellus	97.67	0.00e+00	2107.00
IUUC-Csa-023765	Chlorocebus sabaeus	98.88	0.00e+00	2106.00
IUUC-Cho-024614	Choloepus hoffmanni	98.64	0.00e+00	868.00
IUUC-Cin-025532	Ciona intestinalis	36.46	8.00e-163	567.00
IUUC-Csv-025834	Ciona savignyi	52.26	2.00e-48	184.00
IUUC-Dre-028223	Danio rerio	76.46	0.00e+00	1608.00
IUUC-Dno-029785	Dasypus novemcinctus	96.65	0.00e+00	2087.00
IUUC-Dor-030421	Dipodomys ordii	94.69	0.00e+00	1999.00
IUUC-Dme-031715	Drosophila melanogaster	35.06	1.00e-132	467.00
IUUC-Ete-032767	Echinops telfairi	95.60	0.00e+00	1335.00
IUUC-Eca-033587	Equus caballus	97.58	0.00e+00	2102.00
IUUC-Fca-035622	Felis catus	98.32	0.00e+00	2156.00
IUUC-Fal-037262	Ficedula albicollis	87.00	0.00e+00	1888.00
IUUC-Gmo-038686	Gadus morhua	72.55	0.00e+00	1573.00
IUUC-Gga-041222	Gallus gallus	87.47	0.00e+00	1932.00
IUUC-Gac-042637	Gasterosteus aculeatus	73.20	0.00e+00	1565.00
IUUC-Ggo-044685	Gorilla gorilla	99.72	0.00e+00	2159.00
IUUC-Hsa-046176	Homo sapiens	98.97	0.00e+00	2135.00
IUUC-Itr-048469	Ictidomys tridecemlineatus	98.89	0.00e+00	1066.00
IUUC-Lch-049630	Latimeria chalumnae	79.91	0.00e+00	1738.00
IUUC-Loc-052727	Lepisosteus oculatus	76.13	0.00e+00	1641.00
IUUC-Laf-054041	Loxodonta africana	94.87	0.00e+00	2091.00
IUUC-Mcc-055099	Macaca mulatta	97.70	0.00e+00	2124.00
IUUC-Meu-055991	Macropus eugenii	90.51	0.00e+00	1964.00
IUUC-Mga-059596	Meleagris gallopavo	87.45	0.00e+00	1770.00
IUUC-Mmr-061244	Microcebus murinus	96.33	0.00e+00	1738.00
IUUC-Mdo-062335	Monodelphis domestica	89.95	0.00e+00	1919.00
IUUC-Mmu-063572	Mus musculus	94.87	0.00e+00	2073.00
IUUC-Mpu-066444	Mustela putorius furo	93.13	0.00e+00	2018.00
IUUC-Mlu-068232	Myotis lucifugus	95.62	0.00e+00	2076.00
IUUC-Nle-070036	Nomascus leucogenys	99.63	0.00e+00	2155.00
IUUC-Opr-070503	Ochotona princeps	92.51	0.00e+00	1379.00
IUUC-Ont-072389	Oreochromis niloticus	75.05	0.00e+00	1598.00
IUUC-Oan-073114	Ornithorhynchus anatinus	87.55	0.00e+00	1711.00
IUUC-Ocu-074370	Oryctolagus cuniculus	96.76	0.00e+00	1833.00
IUUC-Ola-086562	Oryzias latipes	72.57	0.00e+00	1582.00
IUUC-Oga-088146	Otolemur garnettii	97.65	0.00e+00	2103.00
IUUC-Oar-089190	Ovis aries	96.18	0.00e+00	2055.00
IUUC-Pan-092271	Papio anubis	98.88	0.00e+00	2134.00
IUUC-Psi-093730	Pelodiscus sinensis	85.68	0.00e+00	1897.00
IUUC-Pma-094120	Petromyzon marinus	77.05	4.00e-132	463.00
IUUC-Pfo-097077	Poecilia formosa	72.53	0.00e+00	1552.00
IUUC-Pab-098069	Pongo abelii	99.35	0.00e+00	2119.00
IUUC-Pca-100762	Procavia capensis	94.41	0.00e+00	1974.00
IUUC-Pva-103149	Pteropus vampyrus	97.76	0.00e+00	2117.00
IUUC-Rno-105342	Rattus norvegicus	94.60	0.00e+00	2071.00
IUUC-Sha-106555	Sarcophilus harrisii	90.51	0.00e+00	1960.00
IUUC-Sly-110848	Solanum lycopersicum	38.98	2.00e-76	280.00
IUUC-Sar-113131	Sorex araneus	91.10	0.00e+00	1193.00
IUUC-Ssc-115841	Sus scrofa	96.93	0.00e+00	2090.00
IUUC-Tgu-116823	Taeniopygia guttata	86.09	0.00e+00	1860.00
IUUC-Tru-118249	Takifugu rubripes	72.69	0.00e+00	1563.00
IUUC-Tsy-119112	Tarsius syrichta	99.74	0.00e+00	753.00
IUUC-Tni-119848	Tetraodon nigroviridis	73.11	0.00e+00	1541.00
IUUC-Tbe-127889	Tupaia belangeri	85.47	0.00e+00	879.00
IUUC-Ttr-129300	Tursiops truncatus	88.17	0.00e+00	1177.00
IUUC-Vpa-130215	Vicugna pacos	97.11	0.00e+00	2090.00
IUUC-Xtr-132107	Xenopus tropicalis	80.00	0.00e+00	1696.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence