iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Fca-035969

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02171177

Gene Name

USP35

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000007458.3	ENSFCAT00000007460.3	ENSFCAP00000006913.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	4.30e-83	279.3	274	744

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqq 90
           Gl NlgNtCY+NS+LQ+L++ +++r+++l+     l e+    ++++l+++lq lf+ l +s++ a+sp+++l+a +   + fs   qq
   Q: 274  GLINLGNTCYVNSILQALFMASDFRHCVLR-----LTEN----NSQPLMTKLQWLFAFLEHSQRPAISPENFLSASW--TPWFSPGTQQ 351
           9*****************************.....4433....3579***************************998..677******* PP
   S: 91   DaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgk 179
           D++E+l++lld+l+ee      k+ ++ +++ k+++s + +e++++ +++ ++++F+g++ ++i+cl+c nvssree f+dlsl++p  
   Q: 352  DCSEYLKYLLDRLHEEE-----KTGTRICQKLKQSSSPSPPEEPPSPSPTSVEKMFGGKIVTRIRCLHCLNVSSREEAFTDLSLAFPPT 435
           *****************.....67888888889999999999*********************************************99 PP
   S: 180  eetkke................................................................................... 185
           + +  +                                                                                   
   Q: 436  DRCRRRrlgsvmlpaedvgvgdppspsqaqvpsrvgsrrqrkhcvtgdaptavldieglgpqgpggqisgeekvereeeveeeareeer 524
           9887779********************************************************************************** PP
   S: 186  .....................................................slqdcLesftkeeelegenkyycekckkkqeaekkl 221
                                                                s+ d+ + f ++e+l+ en+yyce c ++q+aek +
   Q: 525  preqeeeeekekeavaeeeekaekekeaetakekeedgtgpgsqrgaagegsrSVLDLVNYFLSPERLTAENRYYCEPCASLQDAEKAV 613
           ***************************************************************************************** PP
   S: 222  klkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspeekqkekkkYeLiavvvHsG.slssGHYvayvkn........ 301
           +l++ P++Lil L Rfsf+ + ++r+ki + v++pl L l     +        + Y+L++vvvHsG s++sGHY++y+++        
   Q: 614  ELSQGPRYLILTLLRFSFDLRSMRRRKILDDVSIPLLLRLPLAGGR-------GQAYDLCSVVVHSGvSSESGHYYCYAREgaarpaps 695
           ***********************************99999855555.......89**************************99999999 PP
   S: 302  ........ekgkWllfdDskVtevkeeevleetg....staYvlfYkrr 338
                    +++W+lf+D++V+ ++ e+v + t+    +taYvlfY++r
   Q: 696  lgaadrpePENQWYLFNDTRVSFSSFESVSNVTSffpkDTAYVLFYRQR 744
           999999888999*******************999************985 PP

Organism

Felis catus

Protein Sequence
(Fasta)

XRCLGRFRCP AEGEEGAVEF LEQAQQVSGL LAQLWRAQPA AILPCLKELF AVISCTEEEP 60
PSSALASVVQ HLPLELMDGV VRNLSNDDSV TDSQMLTAIS RMIDWVSWPL GKNIDKWIIA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NNGCGCTGCC TGGGTCGCTT CCGTTGTCCG GCCGAGGGCG AGGAGGGCGC CGTGGAGTTC 60
CTGGAGCAGG CCCAGCAGGT GAGCGGGCTC CTGGCGCAGC TGTGGCGCGC TCAGCCCGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016024--ARM-type_fold
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001744	Ailuropoda melanoleuca	96.95	0.00e+00	922.00
IUUC-Aca-005070	Anolis carolinensis	67.18	3.00e-168	585.00
IUUC-Bta-012545	Bos taurus	92.20	0.00e+00	883.00
IUUC-Cja-019731	Callithrix jacchus	93.28	0.00e+00	893.00
IUUC-Cfa-020095	Canis familiaris	98.37	0.00e+00	952.00
IUUC-Cpo-021961	Cavia porcellus	92.48	0.00e+00	879.00
IUUC-Csa-023167	Chlorocebus sabaeus	93.08	0.00e+00	875.00
IUUC-Dno-029186	Dasypus novemcinctus	82.63	0.00e+00	716.00
IUUC-Dor-030538	Dipodomys ordii	99.45	0.00e+00	743.00
IUUC-Ete-032512	Echinops telfairi	91.70	4.00e-108	385.00
IUUC-Eca-033279	Equus caballus	98.15	0.00e+00	822.00
IUUC-Eeu-035120	Erinaceus europaeus	68.02	2.00e-176	612.00
IUUC-Ggo-045323	Gorilla gorilla	93.48	0.00e+00	881.00
IUUC-Hsa-046124	Homo sapiens	93.89	0.00e+00	886.00
IUUC-Itr-048704	Ictidomys tridecemlineatus	95.71	0.00e+00	906.00
IUUC-Laf-053999	Loxodonta africana	90.49	0.00e+00	867.00
IUUC-Mcc-055266	Macaca mulatta	91.68	0.00e+00	856.00
IUUC-Meu-056906	Macropus eugenii	82.48	0.00e+00	808.00
IUUC-Mmr-061720	Microcebus murinus	94.13	0.00e+00	717.00
IUUC-Mmu-063298	Mus musculus	92.06	0.00e+00	887.00
IUUC-Mpu-066195	Mustela putorius furo	96.74	0.00e+00	927.00
IUUC-Mlu-067583	Myotis lucifugus	89.47	0.00e+00	795.00
IUUC-Opr-070454	Ochotona princeps	90.96	4.00e-82	300.00
IUUC-Ocu-074121	Oryctolagus cuniculus	85.08	0.00e+00	717.00
IUUC-Oga-088593	Otolemur garnettii	93.78	0.00e+00	892.00
IUUC-Oar-090140	Ovis aries	91.40	0.00e+00	870.00
IUUC-Pan-092168	Papio anubis	93.28	0.00e+00	876.00
IUUC-Pab-097614	Pongo abelii	93.08	0.00e+00	878.00
IUUC-Pca-100683	Procavia capensis	86.94	0.00e+00	831.00
IUUC-Pva-103146	Pteropus vampyrus	85.13	0.00e+00	837.00
IUUC-Rno-105061	Rattus norvegicus	92.06	0.00e+00	892.00
IUUC-Sha-106686	Sarcophilus harrisii	79.72	0.00e+00	794.00
IUUC-Tsy-119505	Tarsius syrichta	79.74	2.00e-166	579.00
IUUC-Tbe-127723	Tupaia belangeri	89.55	6.00e-93	335.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence