iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Dre-027609

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Protein inhibitor of-activated STAT, 4a

Genbank Nucleotide ID

BX088720

Gene Name

pias4a

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000007081.9	ENSDART00000105520.3	ENSDARP00000096293.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	59.01	1.00e-140	497.00	IUUC-Hsa-045784
E3 activity/RING/RING	33.92	1.00e-28	122.00	IUUC-Sce-106398

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Danio rerio

Protein Sequence
(Fasta)

XAKMAAELVE AMNMVKSFRV SDLQTLLASM GRSKSGLKQD LVGRALRLVQ TEYSPELLKN 60
VRQLYETRFP KASAWLAARR PETVAVNYPA LNSSPRGTGQ GTDYLNGIPK PAPPPAAEVK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGCGAAGAT GGCGGCCGAA CTGGTAGAAG CGATGGTGAG TAGAAGAGAT TTGTAAAAAT 60
AGTGGTATTA CAAGCAGCCA GGTGATCCAA AGGCGGTGGT TACGGAAGCA ACACGAGTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR027224--PIAS4
IPR023321--PINIT
IPR003034--SAP_dom
IPR004181--Znf_MIZ

PROSITE

PS51466--PINIT
PS50800--SAP
PS51044--ZF_SP_RING

Pfam

PF14324--PINIT
PF02891--zf-MIZ

SMART

SM00513--SAP

Gene Ontology

GO:0005634--C:nucleus
GO:0019789--F:SUMO transferase activity
GO:0008270--F:zinc ion binding
GO:0032480--P:negative regulation of type I interferon production
GO:0060339--P:negative regulation of type I interferon-mediated signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001745	Ailuropoda melanoleuca	60.42	9.00e-143	500.00
IUUC-Apl-003765	Anas platyrhynchos	58.31	1.00e-145	509.00
IUUC-Ani-009389	Aspergillus nidulans	29.89	5.00e-29	122.00
IUUC-Aor-009912	Aspergillus oryzae	42.03	1.00e-25	111.00
IUUC-Ate-010496	Aspergillus terreus	34.98	2.00e-30	126.00
IUUC-Ame-010763	Astyanax mexicanus	88.34	0.00e+00	816.00
IUUC-Bta-012369	Bos taurus	61.64	3.00e-150	525.00
IUUC-Cja-019450	Callithrix jacchus	63.20	1.00e-147	516.00
IUUC-Cfa-020933	Canis familiaris	61.19	3.00e-150	525.00
IUUC-Cpo-022112	Cavia porcellus	60.09	1.00e-147	516.00
IUUC-Csa-023913	Chlorocebus sabaeus	50.22	4.00e-106	378.00
IUUC-Dno-029664	Dasypus novemcinctus	56.33	6.00e-101	362.00
IUUC-Ete-032988	Echinops telfairi	57.41	2.00e-95	342.00
IUUC-Eca-034430	Equus caballus	59.95	9.00e-146	510.00
IUUC-Fal-037449	Ficedula albicollis	58.28	1.00e-143	503.00
IUUC-Fso-038103	Fusarium solani	34.26	4.00e-28	119.00
IUUC-Gmo-038925	Gadus morhua	79.88	0.00e+00	737.00
IUUC-Ggr-039896	Gaeumannomyces graminis	33.18	3.00e-32	133.00
IUUC-Gga-040362	Gallus gallus	59.91	7.00e-151	527.00
IUUC-Gac-042353	Gasterosteus aculeatus	81.78	0.00e+00	712.00
IUUC-Ggo-044810	Gorilla gorilla	58.11	2.00e-139	489.00
IUUC-Hsa-045784	Homo sapiens	60.59	9.00e-149	520.00
IUUC-Itr-048486	Ictidomys tridecemlineatus	60.19	8.00e-145	507.00
IUUC-Kpa-049203	Komagataella pastoris	24.59	8.00e-24	106.00
IUUC-Lch-049727	Latimeria chalumnae	58.65	2.00e-116	412.00
IUUC-Loc-052354	Lepisosteus oculatus	66.73	6.00e-167	580.00
IUUC-Laf-054261	Loxodonta africana	60.50	1.00e-147	516.00
IUUC-Mcc-054931	Macaca mulatta	60.59	7.00e-149	520.00
IUUC-Meu-056468	Macropus eugenii	56.37	1.00e-148	520.00
IUUC-Mor-057185	Magnaporthe oryzae	31.88	3.00e-27	116.00
IUUC-Mpo-057405	Magnaporthe poae	34.62	9.00e-32	131.00
IUUC-Mla-058882	Melampsora laricipopulina	35.53	1.00e-24	108.00
IUUC-Mga-059981	Meleagris gallopavo	61.10	7.00e-133	467.00
IUUC-Mmr-061181	Microcebus murinus	57.27	2.00e-135	476.00
IUUC-Mdo-062345	Monodelphis domestica	56.76	2.00e-149	522.00
IUUC-Mmu-063197	Mus musculus	60.87	4.00e-149	521.00
IUUC-Mpu-066275	Mustela putorius furo	60.05	9.00e-146	510.00
IUUC-Mlu-067194	Myotis lucifugus	60.91	4.00e-148	518.00
IUUC-Ncr-068929	Neurospora crassa	33.76	2.00e-28	120.00
IUUC-Ont-072227	Oreochromis niloticus	81.26	0.00e+00	750.00
IUUC-Oba-075731	Oryza barthii	40.00	4.00e-20	94.00
IUUC-Ogl-077808	Oryza glaberrima	40.00	4.00e-20	94.00
IUUC-Oin-079070	Oryza indica	31.46	2.00e-20	94.70
IUUC-Oru-084716	Oryza rufipogon	31.28	2.00e-20	94.70
IUUC-Ola-086865	Oryzias latipes	80.00	0.00e+00	742.00
IUUC-Olu-087742	Ostreococcus lucimarinus	35.48	7.00e-10	58.50
IUUC-Oga-088945	Otolemur garnettii	60.36	7.00e-149	520.00
IUUC-Oar-089412	Ovis aries	63.21	5.00e-144	504.00
IUUC-Ptr-091550	Pan troglodytes	52.89	2.00e-104	372.00
IUUC-Pan-092183	Papio anubis	60.59	7.00e-149	520.00
IUUC-Psi-093003	Pelodiscus sinensis	57.96	3.00e-144	504.00
IUUC-Ppa-095583	Physcomitrella patens	34.29	3.00e-21	97.40
IUUC-Pfo-096704	Poecilia formosa	82.51	0.00e+00	753.00
IUUC-Pab-097923	Pongo abelii	62.47	1.00e-135	476.00
IUUC-Pca-100249	Procavia capensis	58.95	2.00e-93	336.00
IUUC-Pva-102562	Pteropus vampyrus	57.81	6.00e-136	477.00
IUUC-Rno-105762	Rattus norvegicus	61.05	3.00e-150	525.00
IUUC-Sce-106398	Saccharomyces cerevisiae	33.33	4.00e-29	123.00
IUUC-Sha-107253	Sarcophilus harrisii	56.23	6.00e-146	510.00
IUUC-Smo-109174	Selaginella moellendorffii	37.08	2.00e-14	75.10
IUUC-Sre-115069	Sporisorium reilianum	33.33	4.00e-22	100.00
IUUC-Ssc-115241	Sus scrofa	61.42	2.00e-149	522.00
IUUC-Tgu-116884	Taeniopygia guttata	60.09	1.00e-144	506.00
IUUC-Tru-118031	Takifugu rubripes	82.42	0.00e+00	767.00
IUUC-Tni-119766	Tetraodon nigroviridis	84.95	0.00e+00	759.00
IUUC-Tre-122003	Trichoderma reesei	33.05	3.00e-31	129.00
IUUC-Ttr-128556	Tursiops truncatus	53.21	1.00e-118	420.00
IUUC-Uma-129549	Ustilago maydis	37.50	3.00e-26	114.00
IUUC-Vvi-131541	Vitis vinifera	27.59	1.00e-20	95.50
IUUC-Xtr-131866	Xenopus tropicalis	59.72	2.00e-140	492.00
IUUC-Xma-133963	Xiphophorus maculatus	82.84	0.00e+00	729.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence