iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Sha-107253

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01068943

Gene Name

PIAS4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000008283.1	ENSSHAT00000009658.1	ENSSHAP00000009575.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	86.50	0.00e+00	860.00	IUUC-Hsa-045784
E3 activity/RING/RING	34.10	3.00e-28	121.00	IUUC-Sce-106398

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

VGDNLVEDKN MVMSFRVSDL QMLLGFVGRS KSGLKHELVT RALQLVQFDC SPEVFKKIKE 60
LYETRYAKKS SDPVQPHRPL DPLSIHSSYD RGSTVPRTSI STPNIDYPVL YGKYLNGLGR 120

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Nucleotide Sequence
(Fasta)

GTCGGGGACA ATTTAGTGGA AGATAAGGTT CTTAAGCTAG AACATGAAAG ATAGAAGTGG 60
GGAATATACT CAGGATAGAG AGGATGTCCT GGGCAAAGAT ATGGATGTGA GTTAGTGACT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR027224--PIAS4
IPR023321--PINIT
IPR003034--SAP_dom
IPR004181--Znf_MIZ

PROSITE

PS51466--PINIT
PS50800--SAP
PS51044--ZF_SP_RING

Pfam

PF14324--PINIT
PF02891--zf-MIZ

SMART

SM00513--SAP

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016363--C:nuclear matrix
GO:0005654--C:nucleoplasm
GO:1990234--C:transferase complex
GO:0003677--F:DNA binding
GO:0061665--F:SUMO ligase activity
GO:0003714--F:transcription corepressor activity
GO:0008270--F:zinc ion binding
GO:0032088--P:negative regulation of NF-kappaB transcription factor activity
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0010804--P:negative regulation of tumor necrosis factor-mediated signaling pathway
GO:1902231--P:positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:1902174--P:positive regulation of keratinocyte apoptotic process
GO:0033235--P:positive regulation of protein sumoylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001745	Ailuropoda melanoleuca	85.49	0.00e+00	846.00
IUUC-Apl-003765	Anas platyrhynchos	88.98	0.00e+00	866.00
IUUC-Ame-010763	Astyanax mexicanus	54.29	4.00e-143	501.00
IUUC-Bta-012369	Bos taurus	86.77	0.00e+00	865.00
IUUC-Cja-019450	Callithrix jacchus	85.49	0.00e+00	852.00
IUUC-Cfa-020933	Canis familiaris	86.43	0.00e+00	856.00
IUUC-Cpo-022112	Cavia porcellus	86.50	0.00e+00	829.00
IUUC-Csa-023913	Chlorocebus sabaeus	74.95	0.00e+00	688.00
IUUC-Cgl-026533	Colletotrichum gloeosporioides	26.48	4.00e-32	132.00
IUUC-Cme-027209	Cyanidioschyzon merolae	36.17	5.00e-13	69.70
IUUC-Dre-027609	Danio rerio	54.86	8.00e-139	486.00
IUUC-Dno-029664	Dasypus novemcinctus	70.27	9.00e-151	527.00
IUUC-Ete-032988	Echinops telfairi	85.80	2.00e-161	561.00
IUUC-Eca-034430	Equus caballus	85.63	0.00e+00	835.00
IUUC-Fca-035968	Felis catus	92.12	3.00e-160	557.00
IUUC-Fal-037449	Ficedula albicollis	87.93	0.00e+00	840.00
IUUC-Fso-038103	Fusarium solani	34.72	1.00e-26	114.00
IUUC-Gmo-038925	Gadus morhua	59.46	1.00e-135	476.00
IUUC-Ggr-039896	Gaeumannomyces graminis	32.91	1.00e-30	127.00
IUUC-Gga-040362	Gallus gallus	90.73	0.00e+00	885.00
IUUC-Gac-042353	Gasterosteus aculeatus	57.37	1.00e-128	452.00
IUUC-Ggo-044810	Gorilla gorilla	84.15	0.00e+00	813.00
IUUC-Hsa-045784	Homo sapiens	86.50	0.00e+00	860.00
IUUC-Itr-048486	Ictidomys tridecemlineatus	85.18	0.00e+00	848.00
IUUC-Lch-049727	Latimeria chalumnae	72.27	8.00e-151	526.00
IUUC-Loc-052354	Lepisosteus oculatus	51.98	1.00e-124	439.00
IUUC-Laf-054261	Loxodonta africana	85.85	0.00e+00	864.00
IUUC-Mcc-054931	Macaca mulatta	86.30	0.00e+00	850.00
IUUC-Meu-056468	Macropus eugenii	97.77	0.00e+00	937.00
IUUC-Mor-057185	Magnaporthe oryzae	31.00	2.00e-25	110.00
IUUC-Mga-059981	Meleagris gallopavo	93.09	0.00e+00	720.00
IUUC-Mvi-060421	Microbotryum violaceum	29.01	1.00e-29	124.00
IUUC-Mmr-061181	Microcebus murinus	84.22	0.00e+00	814.00
IUUC-Mdo-062345	Monodelphis domestica	98.58	0.00e+00	939.00
IUUC-Mmu-063197	Mus musculus	81.01	0.00e+00	805.00
IUUC-Mpu-066275	Mustela putorius furo	86.79	0.00e+00	857.00
IUUC-Mlu-067194	Myotis lucifugus	86.63	0.00e+00	860.00
IUUC-Ncr-068929	Neurospora crassa	28.04	2.00e-27	116.00
IUUC-Ont-072227	Oreochromis niloticus	57.82	6.00e-135	473.00
IUUC-Obr-076179	Oryza brachyantha	42.86	3.00e-20	94.00
IUUC-Ola-086865	Oryzias latipes	56.10	4.00e-134	471.00
IUUC-Oga-088945	Otolemur garnettii	86.72	0.00e+00	863.00
IUUC-Oar-089412	Ovis aries	84.99	0.00e+00	833.00
IUUC-Ptr-091550	Pan troglodytes	80.59	7.00e-176	609.00
IUUC-Pan-092183	Papio anubis	86.50	0.00e+00	860.00
IUUC-Psi-093003	Pelodiscus sinensis	91.06	0.00e+00	876.00
IUUC-Pfo-096704	Poecilia formosa	57.21	9.00e-137	479.00
IUUC-Pab-097923	Pongo abelii	91.86	0.00e+00	728.00
IUUC-Pca-100249	Procavia capensis	71.70	6.00e-141	493.00
IUUC-Pva-102562	Pteropus vampyrus	82.97	0.00e+00	805.00
IUUC-Rno-105762	Rattus norvegicus	80.81	0.00e+00	810.00
IUUC-Sce-106398	Saccharomyces cerevisiae	34.10	1.00e-28	121.00
IUUC-Sja-107662	Schizosaccharomyces japonicus	31.05	3.00e-28	120.00
IUUC-Smo-109174	Selaginella moellendorffii	37.08	2.00e-13	71.20
IUUC-Sar-113149	Sorex araneus	82.02	9.00e-124	436.00
IUUC-Ssc-115241	Sus scrofa	86.96	0.00e+00	870.00
IUUC-Tgu-116884	Taeniopygia guttata	84.49	0.00e+00	822.00
IUUC-Tru-118031	Takifugu rubripes	57.82	3.00e-140	491.00
IUUC-Tni-119766	Tetraodon nigroviridis	55.02	2.00e-137	482.00
IUUC-Ttr-128556	Tursiops truncatus	80.18	0.00e+00	715.00
IUUC-Xtr-131866	Xenopus tropicalis	79.21	0.00e+00	779.00
IUUC-Xma-133963	Xiphophorus maculatus	57.01	8.00e-130	456.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence