iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Dre-027546

Ensembl Protein ID

ENSDARP00000106610.3

UniProt Accession

Q6IQU7; Q4V9A0; INT12_DANRE

Genbank Protein ID

AAH96989.1; AAH71306.1

Protein Name

Integrator complex subunit 12

Genbank Nucleotide ID

BC096989; BC071306

Gene Name

ints12; zgc:86602

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000091678.4	ENSDART00000125690.4	ENSDARP00000106610.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	2.30e-08	35.0	164	216

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 4    ClvCgeggedek.slveCekCrewfHpaClklsveeelpnsek..wiCpkCrs 53
           C vC++ + ++  +lveC++C++ +H++C+k++v ++  n+ +  w+C +C++
   Q: 164  CVVCRQMTVTSGnQLVECQECHNLYHQECHKPQVTDKDVNDPRlvWYCARCTR 216
           ******9998856********************988888887789******86 PP

Organism

Danio rerio

Functional Description
(View)

Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing.

Protein Sequence
(Fasta)

MAGTVSLELD PIFLKGLGYL HSKSKDSAEK LKALLDESLA RGSDSIYRNS IKEAEVSKVS 60
LPKMTKQDSK SSSSSSASSS ITTTSSSKSS TSEKSKKESE KRTLEKIRVD PGEGVEPPKK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGGCCACTAA GCCACGCCCT ATTGAGGTCC CCATACTTTT CAAGCGCTTT CTTTCTACTT 60
GCTCTATTTT AATTCGATAC TATAGTCGGA TCATTTCAAG CATTGCTAAG TTAGTTAATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF00628--PHD

SMART

SM00249--PHD

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding

KEGG

dre:415251

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001485	Ailuropoda melanoleuca	65.20	7.00e-94	337.00
IUUC-Apl-003539	Anas platyrhynchos	63.46	4.00e-98	351.00
IUUC-Bta-013090	Bos taurus	59.65	2.00e-84	306.00
IUUC-Cja-019984	Callithrix jacchus	63.16	4.00e-94	338.00
IUUC-Cfa-020068	Canis familiaris	65.20	2.00e-93	336.00
IUUC-Cpo-021446	Cavia porcellus	65.50	2.00e-86	313.00
IUUC-Csa-023385	Chlorocebus sabaeus	64.04	2.00e-91	329.00
IUUC-Cho-025018	Choloepus hoffmanni	64.33	4.00e-92	332.00
IUUC-Dno-029989	Dasypus novemcinctus	62.79	4.00e-93	335.00
IUUC-Eca-033999	Equus caballus	64.43	2.00e-88	320.00
IUUC-Fca-035522	Felis catus	62.79	4.00e-92	332.00
IUUC-Gga-041056	Gallus gallus	63.56	4.00e-94	338.00
IUUC-Gac-042508	Gasterosteus aculeatus	65.77	1.00e-91	330.00
IUUC-Ggo-044647	Gorilla gorilla	65.56	7.00e-70	258.00
IUUC-Hsa-046655	Homo sapiens	64.04	8.00e-92	330.00
IUUC-Loc-052933	Lepisosteus oculatus	73.63	3.00e-102	365.00
IUUC-Laf-054471	Loxodonta africana	64.62	4.00e-101	362.00
IUUC-Mcc-055568	Macaca mulatta	64.04	2.00e-91	329.00
IUUC-Meu-056037	Macropus eugenii	64.12	5.00e-98	351.00
IUUC-Mga-059569	Meleagris gallopavo	62.71	8.00e-93	334.00
IUUC-Mmr-061180	Microcebus murinus	64.04	2.00e-92	333.00
IUUC-Mdo-062528	Monodelphis domestica	65.06	6.00e-96	345.00
IUUC-Mmu-064122	Mus musculus	65.01	4.00e-91	328.00
IUUC-Mpu-066477	Mustela putorius furo	64.91	8.00e-93	334.00
IUUC-Mlu-067081	Myotis lucifugus	64.04	2.00e-94	339.00
IUUC-Nle-069599	Nomascus leucogenys	64.04	2.00e-91	329.00
IUUC-Opr-070713	Ochotona princeps	64.62	3.00e-88	318.00
IUUC-Ont-072565	Oreochromis niloticus	62.27	2.00e-85	309.00
IUUC-Oan-073115	Ornithorhynchus anatinus	67.75	2.00e-84	305.00
IUUC-Ocu-074717	Oryctolagus cuniculus	64.91	2.00e-94	340.00
IUUC-Ola-087458	Oryzias latipes	66.99	1.00e-84	306.00
IUUC-Oga-088704	Otolemur garnettii	63.74	4.00e-92	332.00
IUUC-Oar-089184	Ovis aries	60.23	7.00e-86	311.00
IUUC-Ptr-091021	Pan troglodytes	63.45	8.00e-94	337.00
IUUC-Pan-091963	Papio anubis	64.04	2.00e-91	329.00
IUUC-Psi-093012	Pelodiscus sinensis	64.87	3.00e-94	338.00
IUUC-Pab-097870	Pongo abelii	64.04	8.00e-92	330.00
IUUC-Pca-100164	Procavia capensis	64.04	8.00e-101	360.00
IUUC-Pva-102873	Pteropus vampyrus	65.20	1.00e-92	333.00
IUUC-Rno-104840	Rattus norvegicus	63.45	4.00e-90	325.00
IUUC-Sha-106551	Sarcophilus harrisii	64.77	7.00e-101	360.00
IUUC-Tsy-119236	Tarsius syrichta	52.15	9.00e-91	327.00
IUUC-Tni-120510	Tetraodon nigroviridis	65.18	4.00e-98	351.00
IUUC-Tbe-127947	Tupaia belangeri	63.16	3.00e-83	302.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence