iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pfo-097210

Ensembl Protein ID

ENSPFOP00000005134.2

UniProt Accession

A0A087XH81; A0A087XH81_POEFO

Genbank Protein ID

ENSPFOP00000005134

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AYCK01003535

Gene Name

VAV1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPFOG00000004862.2	ENSPFOT00000005143.2	ENSPFOP00000005134.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	4.40e-20	72.0	788	838

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           ++ yd++a +  eL+l++Gd+++++  ++   gW+kg  e  g+ GlfP+n+ve+
   Q: 788  RARYDFSARDRTELSLREGDTIKIL--KKGHTGWWKG--EVYGRVGLFPSNYVEE 838
           678**********************..9999******..9*************86 PP

Organism

Poecilia formosa

Protein Sequence
(Fasta)

MELWRQCAMW LIECRVLPEN HRVTWEGAQV CDLAQALRDG VLLCQLLNNL LPQAVNLREI 60
NLRPQMSQFL CLKNIRTFLA ICQEKFYLKK NDLFEAFELF DVRDFGKVMN TLSILSHSHV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGTCAGAGG AAAAAGGAAG TTGCGGGATG AAGTTAAAAG CCTTCAACAC AGTGCAGCTC 60
TGCAGAACAC CCACTACGGA AGACAGACAG AAGAAGAGCG CTGAAGTTGA AGTCTGAACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0344--Guanine-nucleotide releasing factor
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0727--SH2 domain
KW-0728--SH3 domain
KW-0862--Zinc

Interpro

IPR022613--CAMSAP_CH
IPR001715--CH-domain
IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR002219--PE/DAG-bd
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR000980--SH2
IPR011511--SH3_2
IPR001452--SH3_domain
IPR028530--Vav

PROSITE

PS50021--CH
PS00741--DH_1
PS50010--DH_2
PS50003--PH_DOMAIN
PS50001--SH2
PS50002--SH3
PS00479--ZF_DAG_PE_1
PS50081--ZF_DAG_PE_2

Pfam

PF00130--C1_1
PF11971--CAMSAP_CH
PF00169--PH
PF00621--RhoGEF
PF00017--SH2
PF00018--SH3_1
PF07653--SH3_2

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN

SMART

SM00109--C1
SM00033--CH
SM00233--PH
SM00325--RhoGEF
SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0005622--C:intracellular
GO:0046872--F:metal ion binding
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0035023--P:regulation of Rho protein signal transduction
GO:0007264--P:small GTPase mediated signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aly-005591	Arabidopsis lyrata	29.09	2.00e-08	53.50
IUUC-Cja-020009	Callithrix jacchus	66.16	0.00e+00	1119.00
IUUC-Cfa-020768	Canis familiaris	66.75	0.00e+00	1099.00
IUUC-Dno-029602	Dasypus novemcinctus	66.16	0.00e+00	1093.00
IUUC-Eca-033682	Equus caballus	66.63	0.00e+00	1105.00
IUUC-Fca-035629	Felis catus	66.08	0.00e+00	1139.00
IUUC-Gmo-039693	Gadus morhua	69.59	0.00e+00	1137.00
IUUC-Gac-041567	Gasterosteus aculeatus	80.30	0.00e+00	1274.00
IUUC-Hsa-045886	Homo sapiens	66.16	0.00e+00	1119.00
IUUC-Itr-048730	Ictidomys tridecemlineatus	64.41	0.00e+00	1059.00
IUUC-Loc-051761	Lepisosteus oculatus	74.15	0.00e+00	1257.00
IUUC-Laf-054537	Loxodonta africana	66.27	0.00e+00	1105.00
IUUC-Mcc-054726	Macaca mulatta	66.75	0.00e+00	1125.00
IUUC-Mmr-060980	Microcebus murinus	65.32	0.00e+00	1100.00
IUUC-Mdo-061926	Monodelphis domestica	64.30	0.00e+00	959.00
IUUC-Mmu-063942	Mus musculus	66.39	0.00e+00	1107.00
IUUC-Mpu-066000	Mustela putorius furo	66.75	0.00e+00	1100.00
IUUC-Mlu-067818	Myotis lucifugus	65.73	0.00e+00	1093.00
IUUC-Ont-072213	Oreochromis niloticus	83.43	0.00e+00	1411.00
IUUC-Ola-087345	Oryzias latipes	78.85	0.00e+00	1305.00
IUUC-Oga-089104	Otolemur garnettii	66.51	0.00e+00	1106.00
IUUC-Oar-089459	Ovis aries	66.12	0.00e+00	1114.00
IUUC-Ptr-090766	Pan troglodytes	64.50	0.00e+00	1013.00
IUUC-Pan-091994	Papio anubis	66.08	0.00e+00	1105.00
IUUC-Psi-093595	Pelodiscus sinensis	64.82	0.00e+00	1079.00
IUUC-Pab-098630	Pongo abelii	65.99	0.00e+00	1087.00
IUUC-Pva-102406	Pteropus vampyrus	64.98	0.00e+00	1042.00
IUUC-Rno-105763	Rattus norvegicus	64.39	0.00e+00	1055.00
IUUC-Sha-106683	Sarcophilus harrisii	67.10	0.00e+00	1162.00
IUUC-Sja-107745	Schizosaccharomyces japonicus	50.00	2.00e-12	65.50
IUUC-Ssc-115338	Sus scrofa	64.67	0.00e+00	1020.00
IUUC-Tru-118199	Takifugu rubripes	78.60	0.00e+00	1281.00
IUUC-Tni-120548	Tetraodon nigroviridis	78.85	0.00e+00	1280.00
IUUC-Vpa-130066	Vicugna pacos	46.15	2.00e-50	194.00
IUUC-Xtr-132410	Xenopus tropicalis	64.02	0.00e+00	1069.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence