iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-093583

Ensembl Protein ID

ENSPSIP00000018672.1

UniProt Accession

K7GEG1; K7GEG1_PELSI

Genbank Protein ID

ENSPSIP00000018672

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01110879

Gene Name

USP1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000016572.1	ENSPSIT00000018758.1	ENSPSIP00000018672.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.30e-66	225.1	23	665

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 47   gellkslqklfeel.......w.....kskkkavsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkk.............. 109
            el++sl++l+ ++       +     ++++ a++pr+ll++l++++++++gy q+DaqE+l+++l +++e+++               
   Q: 23   YELICSLHSLILSVeqlqasfLlnpekYTDELATQPRRLLNTLRELNPMYEGYLQHDAQEVLQCILGNIQETCQVlkkeelknmpveep 111
           37777777777777444444424555578888*****************************************5466677777755554 PP
   S: 110  .....eknkpkeeeeeedkselsde................................................................ 129
                e          +++++++++                                                                
   Q: 112  vahlkE----------KSNQNTENNginspeeddhatsnrtaeesedkpskgngkrksdaesgnakkkskvskeqnaaeenqrqtrskr 190
           443332..........22222222255555667779***************************************************** PP
   S: 130  ......................................................................................... 129
                                                                                                    
   Q: 191  kataeklenhtdaiakysvendsakptqkksrlrlnwfkssgkqpsilskfcsvgklttnlgtkeqmketddyeieaasvkcengnikd 279
           ***************************************************************************************** PP
   S: 130  ...................aeekkkkknk......slisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke........ 185
                               +       +      +l+++lFqgql  +++clec+  ++r+e+f+d+s+pv+++e +k e        
   Q: 280  ycepassvesvgekgieesLQG------DsgladfELVEKLFQGQLVLRTRCLECECFTERREDFQDISVPVQEDELSKVEesseispe 362
           ******9999988766443333......1344556*****************************************99998******** PP
   S: 186  ......slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRf.....sfseeqksrekinkkvefpleLdlsp 263
                 +l++++++f++ e++ ge+ky+ce+c++++eae++l ++k+Pev+++hLk+f     +f+++++  +kin+ + +pl+L+l++
   Q: 363  pktemkTLKWAISQFASVERIVGEDKYFCENCRHYTEAERSLLFDKMPEVITIHLKCFaanglEFDCYGGL-SKINTPLLTPLKLSLEE 450
           *******************************************************************9555.6**************** PP
   S: 264  fctspeekqkekkkYeLiavvvHsG.slssGHYvayvkn.................................................. 301
           + t+p+     +++Y L+avv+HsG ++ssGHY+a vk                                                   
   Q: 451  WSTKPT-----NDTYGLFAVVMHSGiTISSGHYTASVKItdlnsleldkcnfithqmyevikpeplneaearvvaedyddgevsfrvng 534
           ****98.....789*************************************************************************** PP
   S: 302  ......................................................................................... 301
                                                                                                    
   Q: 535  naqssktlskknieavgllggqksksdcdlynnkvtnsdkvsvntltenrnfeststngilefdkstengeafsglenkalyvlqslke 623
           *****************************************************999999999999999999999998888888887776 PP
   S: 302  ekgkWllfdDskVtevkeeevleetg......staYvlfYkr 337
            +gkWllfdDs+V++++e+++l++ +      st+Y+lfYk+
   Q: 624  YEGKWLLFDDSEVKVIEEKDFLNTLSpsssstSTPYLLFYKK 665
           6999*******************888**************97 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

MFKDEGEQKS DKGGCKEDPL ASYELICSLH SLILSVEQLQ ASFLLNPEKY TDELATQPRR 60
LLNTLRELNP MYEGYLQHDA QEVLQCILGN IQETCQVLKK EELKNMPVEE PVAHLKEKSN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGTAACTGC TGATTGCAGC TTTCTGATCT TATTCCCCAT CCCCATTATT ATTTGTGAGG 60
AGAAAAAAAT GCCAGGTGTA TTACCGACTG ACACGGCTGG GCTTTTGAGA GGTAGCCCGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR033815--USP1
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0035520--P:monoubiquitinated protein deubiquitination
GO:0006282--P:regulation of DNA repair
GO:0009411--P:response to UV
GO:0001501--P:skeletal system development
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001939	Ailuropoda melanoleuca	72.96	0.00e+00	904.00
IUUC-Apl-004204	Anas platyrhynchos	83.13	0.00e+00	976.00
IUUC-Aca-004637	Anolis carolinensis	71.04	0.00e+00	875.00
IUUC-Ame-011718	Astyanax mexicanus	48.39	6.00e-142	498.00
IUUC-Bta-012552	Bos taurus	69.84	0.00e+00	871.00
IUUC-Cja-019588	Callithrix jacchus	72.58	0.00e+00	902.00
IUUC-Cfa-020211	Canis familiaris	73.11	0.00e+00	912.00
IUUC-Cpo-021551	Cavia porcellus	66.62	0.00e+00	808.00
IUUC-Csa-024186	Chlorocebus sabaeus	72.51	0.00e+00	901.00
IUUC-Cho-024739	Choloepus hoffmanni	64.77	6.00e-117	414.00
IUUC-Dre-028184	Danio rerio	48.71	9.00e-150	523.00
IUUC-Dno-029669	Dasypus novemcinctus	70.67	0.00e+00	886.00
IUUC-Dor-030168	Dipodomys ordii	66.91	0.00e+00	743.00
IUUC-Ete-032825	Echinops telfairi	67.23	0.00e+00	708.00
IUUC-Eca-033595	Equus caballus	70.88	0.00e+00	884.00
IUUC-Eeu-034877	Erinaceus europaeus	67.84	1.00e-87	317.00
IUUC-Fca-035381	Felis catus	71.19	7.00e-165	573.00
IUUC-Fal-037592	Ficedula albicollis	76.98	0.00e+00	916.00
IUUC-Gmo-039680	Gadus morhua	45.60	2.00e-135	476.00
IUUC-Gga-041196	Gallus gallus	80.74	0.00e+00	978.00
IUUC-Gac-042292	Gasterosteus aculeatus	49.53	3.00e-117	415.00
IUUC-Ggo-044671	Gorilla gorilla	72.08	0.00e+00	904.00
IUUC-Hsa-047020	Homo sapiens	71.94	0.00e+00	900.00
IUUC-Itr-048800	Ictidomys tridecemlineatus	70.35	0.00e+00	847.00
IUUC-Lch-050543	Latimeria chalumnae	59.03	0.00e+00	658.00
IUUC-Loc-052338	Lepisosteus oculatus	52.97	6.00e-170	590.00
IUUC-Laf-053707	Loxodonta africana	71.70	0.00e+00	887.00
IUUC-Mcc-055885	Macaca mulatta	72.51	0.00e+00	903.00
IUUC-Meu-056573	Macropus eugenii	67.77	0.00e+00	806.00
IUUC-Mga-059346	Meleagris gallopavo	82.17	0.00e+00	1015.00
IUUC-Mmr-061612	Microcebus murinus	71.73	0.00e+00	871.00
IUUC-Mdo-062887	Monodelphis domestica	70.50	0.00e+00	827.00
IUUC-Mmu-064044	Mus musculus	69.84	0.00e+00	861.00
IUUC-Mpu-066847	Mustela putorius furo	73.36	0.00e+00	918.00
IUUC-Mlu-067684	Myotis lucifugus	71.81	0.00e+00	891.00
IUUC-Nle-070057	Nomascus leucogenys	72.27	0.00e+00	905.00
IUUC-Opr-070463	Ochotona princeps	69.57	0.00e+00	742.00
IUUC-Ont-071975	Oreochromis niloticus	47.50	1.00e-132	467.00
IUUC-Ocu-074840	Oryctolagus cuniculus	71.73	0.00e+00	875.00
IUUC-Ola-087088	Oryzias latipes	47.67	9.00e-144	503.00
IUUC-Oga-088472	Otolemur garnettii	71.88	0.00e+00	874.00
IUUC-Oar-089498	Ovis aries	69.66	0.00e+00	871.00
IUUC-Ptr-091395	Pan troglodytes	71.94	0.00e+00	900.00
IUUC-Pan-092462	Papio anubis	72.51	0.00e+00	902.00
IUUC-Pfo-096314	Poecilia formosa	46.72	2.00e-130	459.00
IUUC-Pab-098568	Pongo abelii	72.38	0.00e+00	907.00
IUUC-Pca-100948	Procavia capensis	77.49	8.00e-128	451.00
IUUC-Pva-102853	Pteropus vampyrus	70.92	0.00e+00	874.00
IUUC-Rno-105573	Rattus norvegicus	71.28	0.00e+00	873.00
IUUC-Sha-107495	Sarcophilus harrisii	68.05	0.00e+00	838.00
IUUC-Sar-113545	Sorex araneus	59.59	0.00e+00	659.00
IUUC-Ssc-115962	Sus scrofa	71.51	0.00e+00	889.00
IUUC-Tgu-116731	Taeniopygia guttata	76.61	0.00e+00	916.00
IUUC-Tru-117893	Takifugu rubripes	45.68	3.00e-123	435.00
IUUC-Tsy-119644	Tarsius syrichta	79.49	4.00e-134	471.00
IUUC-Tni-119819	Tetraodon nigroviridis	44.30	3.00e-131	462.00
IUUC-Tbe-127272	Tupaia belangeri	67.90	0.00e+00	818.00
IUUC-Ttr-128404	Tursiops truncatus	71.28	0.00e+00	881.00
IUUC-Vpa-130205	Vicugna pacos	71.26	0.00e+00	885.00
IUUC-Xtr-132613	Xenopus tropicalis	55.78	0.00e+00	650.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence