iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000007767.1	ENSSHAT00000009039.1	ENSSHAP00000008965.1
ENSSHAG00000007767.1	ENSSHAT00000009040.1	ENSSHAP00000008966.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	73.98	0.00e+00	640.00	IUUC-Hsa-046950

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MSLSSITAHC SASENACRIS PGQVNQVRPK LPLLKILQAA GAQGEMFTMK EVMHYLGQYI 60
MVKQLYDQQE QHMVYCGGDL LGELLGLQSF SVKDPSPLYD MLRKNLVTAT VTVSTDAAQT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCTACAGATT GCAACTTCAC TGCCAAAATG TCATTATCTT CAATTACTGC ACATTGTTCA 60
GCATCTGAAA ATGCTTGCAG AATTTCACCA GGACAGGTCA ATCAGGTAAC CTGCCTTTAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome

Interpro

IPR015458--MDM4
IPR016495--p53_neg-reg_MDM_2/4
IPR003121--SWIB_MDM2_domain
IPR001876--Znf_RanBP2
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01358--ZF_RANBP2_1
PS50199--ZF_RANBP2_2

Pfam

PF02201--SWIB
PF00641--zf-RanBP

SMART

SM00547--ZnF_RBZ

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0008283--P:cell proliferation
GO:0071456--P:cellular response to hypoxia
GO:0030330--P:DNA damage response, signal transduction by p53 class mediator
GO:0045023--P:G0 to G1 transition
GO:0043066--P:negative regulation of apoptotic process
GO:0071157--P:negative regulation of cell cycle arrest
GO:0042177--P:negative regulation of protein catabolic process
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0006461--P:protein complex assembly
GO:0050821--P:protein stabilization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001467	Ailuropoda melanoleuca	74.24	0.00e+00	668.00
IUUC-Apl-003800	Anas platyrhynchos	64.42	2.00e-166	578.00
IUUC-Aca-004608	Anolis carolinensis	56.22	3.00e-139	488.00
IUUC-Ame-010869	Astyanax mexicanus	48.48	1.00e-111	396.00
IUUC-Bta-013287	Bos taurus	74.80	0.00e+00	707.00
IUUC-Cja-019305	Callithrix jacchus	73.78	0.00e+00	680.00
IUUC-Cfa-020393	Canis familiaris	74.65	0.00e+00	685.00
IUUC-Cpo-022166	Cavia porcellus	73.88	0.00e+00	633.00
IUUC-Csa-023654	Chlorocebus sabaeus	74.59	0.00e+00	666.00
IUUC-Cho-024403	Choloepus hoffmanni	73.41	5.00e-101	360.00
IUUC-Dre-027754	Danio rerio	47.44	9.00e-121	426.00
IUUC-Dno-029630	Dasypus novemcinctus	75.66	0.00e+00	700.00
IUUC-Dor-031064	Dipodomys ordii	57.84	3.00e-156	545.00
IUUC-Ete-032901	Echinops telfairi	69.51	0.00e+00	653.00
IUUC-Eca-034234	Equus caballus	78.86	0.00e+00	777.00
IUUC-Eeu-035015	Erinaceus europaeus	65.96	5.00e-73	268.00
IUUC-Fca-036587	Felis catus	74.80	0.00e+00	700.00
IUUC-Fal-036906	Ficedula albicollis	56.77	9.00e-144	503.00
IUUC-Gmo-038646	Gadus morhua	46.46	3.00e-106	378.00
IUUC-Gga-040124	Gallus gallus	63.53	5.00e-126	443.00
IUUC-Gac-042397	Gasterosteus aculeatus	47.63	1.00e-117	416.00
IUUC-Ggo-045505	Gorilla gorilla	73.98	0.00e+00	672.00
IUUC-Hsa-046950	Homo sapiens	74.19	0.00e+00	675.00
IUUC-Itr-048886	Ictidomys tridecemlineatus	74.39	0.00e+00	685.00
IUUC-Lch-050141	Latimeria chalumnae	54.18	8.00e-130	456.00
IUUC-Loc-051921	Lepisosteus oculatus	47.35	9.00e-121	426.00
IUUC-Laf-054281	Loxodonta africana	72.34	0.00e+00	664.00
IUUC-Mcc-055462	Macaca mulatta	70.99	7.00e-178	616.00
IUUC-Meu-056294	Macropus eugenii	84.80	6.00e-177	613.00
IUUC-Mga-059924	Meleagris gallopavo	63.67	2.00e-176	612.00
IUUC-Mmr-061428	Microcebus murinus	74.19	0.00e+00	718.00
IUUC-Mdo-062643	Monodelphis domestica	90.12	0.00e+00	867.00
IUUC-Mmu-063229	Mus musculus	72.91	0.00e+00	695.00
IUUC-Mpu-065782	Mustela putorius furo	73.28	0.00e+00	671.00
IUUC-Mlu-068105	Myotis lucifugus	66.13	0.00e+00	643.00
IUUC-Nle-069549	Nomascus leucogenys	74.39	0.00e+00	676.00
IUUC-Opr-070568	Ochotona princeps	74.46	0.00e+00	659.00
IUUC-Ont-072276	Oreochromis niloticus	47.90	1.00e-122	433.00
IUUC-Oan-072787	Ornithorhynchus anatinus	76.33	0.00e+00	694.00
IUUC-Ocu-074912	Oryctolagus cuniculus	74.80	0.00e+00	702.00
IUUC-Ola-087037	Oryzias latipes	47.54	1.00e-107	383.00
IUUC-Oga-088953	Otolemur garnettii	72.98	0.00e+00	672.00
IUUC-Oar-089202	Ovis aries	75.00	0.00e+00	712.00
IUUC-Ptr-090964	Pan troglodytes	73.98	0.00e+00	672.00
IUUC-Pan-091975	Papio anubis	74.39	0.00e+00	679.00
IUUC-Psi-093558	Pelodiscus sinensis	65.57	6.00e-172	597.00
IUUC-Pfo-096454	Poecilia formosa	48.90	8.00e-122	430.00
IUUC-Pab-098123	Pongo abelii	74.59	0.00e+00	678.00
IUUC-Pca-101112	Procavia capensis	65.85	2.00e-173	602.00
IUUC-Pva-103098	Pteropus vampyrus	66.67	0.00e+00	635.00
IUUC-Rno-105930	Rattus norvegicus	73.98	0.00e+00	683.00
IUUC-Sar-113584	Sorex araneus	68.91	2.00e-173	601.00
IUUC-Tgu-116766	Taeniopygia guttata	60.00	5.00e-108	383.00
IUUC-Tru-117829	Takifugu rubripes	50.30	2.00e-122	432.00
IUUC-Tsy-119268	Tarsius syrichta	74.36	2.00e-88	319.00
IUUC-Tni-120204	Tetraodon nigroviridis	48.28	9.00e-115	407.00
IUUC-Tbe-127840	Tupaia belangeri	67.74	6.00e-101	360.00
IUUC-Ttr-128863	Tursiops truncatus	73.58	0.00e+00	696.00
IUUC-Uma-129392	Ustilago maydis	33.33	2.80e+00	26.90
IUUC-Vpa-130718	Vicugna pacos	75.32	0.00e+00	677.00
IUUC-Xtr-132320	Xenopus tropicalis	48.86	1.00e-95	343.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence