iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-037340

Ensembl Protein ID

ENSFALP00000014267.1

UniProt Accession

U3KGW3; U3KGW3_FICAL

Genbank Protein ID

ENSFALP00000014267

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01000490

Gene Name

IFT122

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000013670.1	ENSFALT00000014326.1	ENSFALP00000014267.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.10e-16	59.1	51	80

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvW 28
           gH+d v+c+a+  d ++++sGs D+++ +W
   Q: 51   GHKDTVYCVAYaKDgKRFASGSADKSVIIW 80
           8***********777*************** PP

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

MRAALTWRDR AEQCIYDLAF KPDGTQLIIA AGNRLLVYDT SDGTLIQPLK GHKDTVYCVA 60
YAKDGKRFAS GSADKSVIIW TSKLEGILKY THNDSIQCVS YNPLTHQLAS CSSGDFGLWS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG 60
GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG GGGCGGAGAG CGGGACCGGG CCGAGCCGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0036064--C:ciliary basal body
GO:0097546--C:ciliary base
GO:0005829--C:cytosol
GO:0030991--C:intraciliary transport particle A
GO:0016020--C:membrane
GO:0005654--C:nucleoplasm
GO:0032391--C:photoreceptor connecting cilium
GO:0048593--P:camera-type eye morphogenesis
GO:0060830--P:ciliary receptor clustering involved in smoothened signaling pathway
GO:0010172--P:embryonic body morphogenesis
GO:0042733--P:embryonic digit morphogenesis
GO:0035115--P:embryonic forelimb morphogenesis
GO:0060971--P:embryonic heart tube left/right pattern formation
GO:0072594--P:establishment of protein localization to organelle
GO:0035720--P:intraciliary anterograde transport
GO:0035721--P:intraciliary retrograde transport
GO:0050680--P:negative regulation of epithelial cell proliferation
GO:0021914--P:negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning
GO:0001843--P:neural tube closure
GO:1905515--P:non-motile cilium assembly
GO:0061512--P:protein localization to cilium
GO:0007227--P:signal transduction downstream of smoothened
GO:0060831--P:smoothened signaling pathway involved in dorsal/ventral neural tube patterning

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001933	Ailuropoda melanoleuca	83.08	0.00e+00	2097.00
IUUC-Apl-003504	Anas platyrhynchos	91.97	0.00e+00	2241.00
IUUC-Aca-004767	Anolis carolinensis	82.23	0.00e+00	2117.00
IUUC-Ame-011642	Astyanax mexicanus	64.44	0.00e+00	1615.00
IUUC-Bta-012969	Bos taurus	86.52	0.00e+00	1759.00
IUUC-Cel-018670	Caenorhabditis elegans	39.40	0.00e+00	907.00
IUUC-Cja-019249	Callithrix jacchus	78.67	0.00e+00	1584.00
IUUC-Cfa-020915	Canis familiaris	87.08	0.00e+00	1768.00
IUUC-Cpo-021888	Cavia porcellus	85.08	0.00e+00	2115.00
IUUC-Cre-022789	Chlamydomonas reinhardtii	50.77	0.00e+00	1159.00
IUUC-Csa-023533	Chlorocebus sabaeus	83.67	0.00e+00	1693.00
IUUC-Cin-025121	Ciona intestinalis	60.55	0.00e+00	1551.00
IUUC-Csv-026240	Ciona savignyi	58.56	0.00e+00	1444.00
IUUC-Dno-029685	Dasypus novemcinctus	88.31	0.00e+00	2129.00
IUUC-Dme-032005	Drosophila melanogaster	21.51	9.00e-08	52.80
IUUC-Ete-032682	Echinops telfairi	77.06	0.00e+00	1550.00
IUUC-Eca-033831	Equus caballus	83.45	0.00e+00	2116.00
IUUC-Eeu-034919	Erinaceus europaeus	80.07	0.00e+00	948.00
IUUC-Fca-036559	Felis catus	81.92	0.00e+00	2040.00
IUUC-Gga-040595	Gallus gallus	91.05	0.00e+00	2260.00
IUUC-Ggo-045356	Gorilla gorilla	83.27	0.00e+00	1684.00
IUUC-Hsa-046135	Homo sapiens	83.27	0.00e+00	1682.00
IUUC-Itr-048228	Ictidomys tridecemlineatus	77.07	0.00e+00	1688.00
IUUC-Lch-050183	Latimeria chalumnae	80.69	0.00e+00	1158.00
IUUC-Loc-052049	Lepisosteus oculatus	83.03	0.00e+00	2073.00
IUUC-Laf-053728	Loxodonta africana	87.53	0.00e+00	1773.00
IUUC-Mcc-054971	Macaca mulatta	83.87	0.00e+00	1698.00
IUUC-Meu-056446	Macropus eugenii	76.74	0.00e+00	1992.00
IUUC-Mga-059296	Meleagris gallopavo	89.78	0.00e+00	1851.00
IUUC-Mmr-061232	Microcebus murinus	84.78	0.00e+00	1711.00
IUUC-Mdo-062115	Monodelphis domestica	83.59	0.00e+00	2137.00
IUUC-Mmu-063664	Mus musculus	82.50	0.00e+00	2092.00
IUUC-Mpu-066136	Mustela putorius furo	71.51	0.00e+00	1771.00
IUUC-Mlu-068238	Myotis lucifugus	77.89	0.00e+00	1938.00
IUUC-Nle-069003	Nomascus leucogenys	76.53	0.00e+00	1872.00
IUUC-Ont-072080	Oreochromis niloticus	66.03	0.00e+00	1657.00
IUUC-Oan-072891	Ornithorhynchus anatinus	91.09	0.00e+00	954.00
IUUC-Ocu-074262	Oryctolagus cuniculus	79.11	0.00e+00	1947.00
IUUC-Ola-086538	Oryzias latipes	73.92	0.00e+00	1535.00
IUUC-Oga-088722	Otolemur garnettii	86.16	0.00e+00	1729.00
IUUC-Oar-089249	Ovis aries	87.06	0.00e+00	2109.00
IUUC-Ptr-090752	Pan troglodytes	83.37	0.00e+00	1682.00
IUUC-Pan-092472	Papio anubis	80.48	0.00e+00	1989.00
IUUC-Psi-093335	Pelodiscus sinensis	88.94	0.00e+00	2206.00
IUUC-Pma-094520	Petromyzon marinus	71.56	0.00e+00	1642.00
IUUC-Ppa-095600	Physcomitrella patens	59.29	9.00e-39	151.00
IUUC-Pfo-096526	Poecilia formosa	68.56	0.00e+00	1733.00
IUUC-Pab-098428	Pongo abelii	78.49	0.00e+00	974.00
IUUC-Pca-100233	Procavia capensis	83.56	0.00e+00	741.00
IUUC-Pva-103064	Pteropus vampyrus	70.93	0.00e+00	1752.00
IUUC-Rno-105764	Rattus norvegicus	82.42	0.00e+00	2078.00
IUUC-Sha-106649	Sarcophilus harrisii	83.12	0.00e+00	2118.00
IUUC-Smo-109478	Selaginella moellendorffii	42.45	0.00e+00	946.00
IUUC-Tgu-116870	Taeniopygia guttata	89.62	0.00e+00	2185.00
IUUC-Tru-118661	Takifugu rubripes	69.03	0.00e+00	1785.00
IUUC-Tsy-119640	Tarsius syrichta	69.52	9.00e-175	607.00
IUUC-Tni-120812	Tetraodon nigroviridis	67.49	0.00e+00	1682.00
IUUC-Ttr-128862	Tursiops truncatus	79.22	0.00e+00	2019.00
IUUC-Vpa-130049	Vicugna pacos	73.31	2.00e-142	499.00
IUUC-Xtr-131914	Xenopus tropicalis	80.62	0.00e+00	1988.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence