iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bta-013322

Ensembl Protein ID

ENSBTAP00000012594.5

UniProt Accession

E1BK71; E1BK71_BOVIN

Genbank Protein ID

ENSBTAP00000012594

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

DAAA02041599

Gene Name

PACSIN3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000009576.5	ENSBTAT00000012594.5	ENSBTAP00000012594.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.10e-13	50.1	380	434

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           +v++lydy +q+ deL++++G+ +l +  ee ++gW++g+   +g+ Gl P+n+ve 
   Q: 380  RVRALYDYAGQEADELSFRAGEELLKM-SEEDEQGWCQGQ-LQSGRIGLYPANYVEC 434
           689********************9999.999********7.99************85 PP

Organism

Bos taurus

Protein Sequence
(Fasta)

DTMAPEEEAG GEALEGSFWE AGNYRRTVQR VEDGHRLCGD LVSCFQERAR IEKAYAQQLA 60
DWARKWRGAV EKGPQYGTLE KAWHAFFTAA ERLSALHLEV REKLQGQDSE RVRSWQRGAF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCGGCCCGG GAGCGACAGG ACTTGGGTCG GAGCGTGGCC GGACCCCCCC CACCCGCCGA 60
GGCGCCCAGG GAGGACGCGG TGAGTGCTGC CCGGGCGGGG ACGGCGGGGA GGCGGTGGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR027267--AH/BAR-dom
IPR031160--F_BAR
IPR001060--FCH_dom
IPR028523--PACSIN3
IPR001452--SH3_domain

PROSITE

PS51741--F_BAR
PS50002--SH3

Pfam

PF00611--FCH
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00055--FCH
SM00326--SH3

Gene Ontology

GO:0005829--C:cytosol
GO:0005768--C:endosome
GO:0070062--C:extracellular exosome
GO:0005886--C:plasma membrane
GO:0019855--F:calcium channel inhibitor activity
GO:0008289--F:lipid binding
GO:0051926--P:negative regulation of calcium ion transport
GO:0045806--P:negative regulation of endocytosis
GO:0097320--P:plasma membrane tubulation
GO:0051044--P:positive regulation of membrane protein ectodomain proteolysis
GO:0030100--P:regulation of endocytosis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001906	Ailuropoda melanoleuca	83.12	0.00e+00	761.00
IUUC-Apl-003211	Anas platyrhynchos	65.84	6.00e-176	610.00
IUUC-Aca-004256	Anolis carolinensis	66.44	5.00e-178	617.00
IUUC-Ame-011049	Astyanax mexicanus	61.22	1.00e-155	542.00
IUUC-Cja-018907	Callithrix jacchus	90.99	0.00e+00	764.00
IUUC-Cfa-021126	Canis familiaris	92.15	0.00e+00	764.00
IUUC-Cpo-021491	Cavia porcellus	89.38	0.00e+00	750.00
IUUC-Csa-023107	Chlorocebus sabaeus	92.38	0.00e+00	772.00
IUUC-Cne-026895	Cryptococcus neoformans	40.98	4.00e-08	51.60
IUUC-Dre-027933	Danio rerio	60.45	4.00e-148	517.00
IUUC-Dno-029002	Dasypus novemcinctus	90.53	0.00e+00	725.00
IUUC-Eca-033824	Equus caballus	91.69	0.00e+00	768.00
IUUC-Eeu-035122	Erinaceus europaeus	81.77	1.00e-168	585.00
IUUC-Fca-036420	Felis catus	93.07	0.00e+00	795.00
IUUC-Fal-037277	Ficedula albicollis	65.76	3.00e-178	617.00
IUUC-Gga-040941	Gallus gallus	65.84	1.00e-176	612.00
IUUC-Gac-041374	Gasterosteus aculeatus	63.64	2.00e-140	491.00
IUUC-Ggo-045211	Gorilla gorilla	91.95	0.00e+00	773.00
IUUC-Hsa-046053	Homo sapiens	92.38	0.00e+00	772.00
IUUC-Itr-047939	Ictidomys tridecemlineatus	90.99	0.00e+00	764.00
IUUC-Loc-052808	Lepisosteus oculatus	63.84	8.00e-161	560.00
IUUC-Laf-054211	Loxodonta africana	90.07	0.00e+00	744.00
IUUC-Mcc-055044	Macaca mulatta	92.38	0.00e+00	772.00
IUUC-Mga-059216	Meleagris gallopavo	65.91	5.00e-177	613.00
IUUC-Mmr-061172	Microcebus murinus	92.15	0.00e+00	776.00
IUUC-Mdo-062600	Monodelphis domestica	84.30	0.00e+00	744.00
IUUC-Mmu-063218	Mus musculus	89.38	0.00e+00	751.00
IUUC-Mpu-066819	Mustela putorius furo	80.68	0.00e+00	759.00
IUUC-Mlu-067597	Myotis lucifugus	91.03	0.00e+00	781.00
IUUC-Nle-069195	Nomascus leucogenys	91.92	0.00e+00	768.00
IUUC-Opr-071050	Ochotona princeps	91.45	0.00e+00	749.00
IUUC-Ont-071612	Oreochromis niloticus	57.05	4.00e-143	501.00
IUUC-Oan-073256	Ornithorhynchus anatinus	83.83	0.00e+00	713.00
IUUC-Ocu-074653	Oryctolagus cuniculus	92.12	0.00e+00	738.00
IUUC-Oga-089040	Otolemur garnettii	90.53	0.00e+00	766.00
IUUC-Oar-089918	Ovis aries	94.99	0.00e+00	789.00
IUUC-Ptr-091307	Pan troglodytes	92.38	0.00e+00	772.00
IUUC-Pan-092512	Papio anubis	92.38	0.00e+00	772.00
IUUC-Pfo-096881	Poecilia formosa	61.68	5.00e-154	537.00
IUUC-Pab-098620	Pongo abelii	92.38	0.00e+00	772.00
IUUC-Pva-102464	Pteropus vampyrus	88.91	0.00e+00	736.00
IUUC-Rno-106091	Rattus norvegicus	89.38	0.00e+00	751.00
IUUC-Sha-107474	Sarcophilus harrisii	85.95	0.00e+00	744.00
IUUC-Ssc-116128	Sus scrofa	92.61	0.00e+00	775.00
IUUC-Tgu-117511	Taeniopygia guttata	63.77	8.00e-173	600.00
IUUC-Tru-118005	Takifugu rubripes	61.14	6.00e-142	497.00
IUUC-Tni-119851	Tetraodon nigroviridis	63.38	9.00e-143	499.00
IUUC-Ttr-129313	Tursiops truncatus	92.38	0.00e+00	788.00
IUUC-Vpa-130760	Vicugna pacos	97.81	2.00e-95	342.00
IUUC-Xtr-132697	Xenopus tropicalis	56.02	1.00e-135	476.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence