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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Rno-104837
UUCD1 version UUC-RaN-00052
Ensembl Protein ID ENSRNOP00000025399.4
UniProt Accession B2RZ17; FBXW2_RAT
Genbank Protein ID EDL93165.1; EDL93166.1; AAI66990.1
Protein Name F-box/WD repeat-containing protein 2; F-box and WD-40 domain-containing protein 2; Protein MD6
Genbank Nucleotide ID CH474001; CH474001; BC166990
Gene Name Fbxw2
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSRNOG00000018687.5 ENSRNOT00000025399.4 ENSRNOP00000025399.4
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpress
DNA & RNA Element
TRANSFACRAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
CPLMPhosphositePlus
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 4.80e-22 77.5 146 181
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclafsdtllvsGsdDgtikvWDlrtgvll 36
           gH+++v++l + d+ll++GsdD + k+WD++tg ++
   Q: 146  GHSARVYALYYKDGLLCTGSDDLSAKLWDVSTGQCV 181
           8********8877********************997 PP
   
Organism Rattus norvegicus
Functional Description
(View)

Functional Description


     Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.
 Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.
Protein Sequence
(Fasta)
MERKDFETWL DNISVTFLSL TDLQKNETLD HLISLSGAVQ LRHLSNNLET LLKRDFLKLL 60
PLELSFYLLK WLDPQTLLTC CLVSKQWNKV ISACTEVWQT ACKNLGWQID DSVQDALHWK 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Rno-104837|E3,WD_repeat|Rattus norvegicus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CTCCCTTTCC CCGCAGGCGC CATGGCTGCG GAGCGGACCC GGCCGCTGCG ACGCTCTGGC 60
GGCCCGAGCG CGCCTAGTCG GTGTGAGCCC GGCGCGAGGT CCCGGGCCCC GGGGCGCTCG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Rno-104837|E3,WD_repeat|Rattus norvegicus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0007--Acetylation
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0833--Ubl conjugation pathway
KW-0853--WD repeat
Interpro

IPR001810--F-box_dom
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS50181--FBOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF12937--F-box-like
PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM00256--FBOX
SM00320--WD40
KEGG rno:311881
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001726 Ailuropoda melanoleuca 98.68 0.00e+00 884.00
IUUC-Apl-003329 Anas platyrhynchos 93.39 0.00e+00 845.00
IUUC-Aca-004491 Anolis carolinensis 91.10 7.00e-154 536.00
IUUC-Ame-011713 Astyanax mexicanus 80.66 0.00e+00 739.00
IUUC-Bta-012538 Bos taurus 98.24 0.00e+00 879.00
IUUC-Cja-018833 Callithrix jacchus 98.68 0.00e+00 884.00
IUUC-Cfa-020233 Canis familiaris 98.68 0.00e+00 884.00
IUUC-Cpo-021662 Cavia porcellus 98.68 0.00e+00 883.00
IUUC-Csa-023818 Chlorocebus sabaeus 98.68 0.00e+00 884.00
IUUC-Cin-025489 Ciona intestinalis 30.94 2.00e-41 162.00
IUUC-Dre-028713 Danio rerio 79.34 0.00e+00 720.00
IUUC-Dno-029701 Dasypus novemcinctus 97.80 0.00e+00 874.00
IUUC-Dor-030944 Dipodomys ordii 98.68 0.00e+00 882.00
IUUC-Ete-033151 Echinops telfairi 96.92 0.00e+00 858.00
IUUC-Eca-033984 Equus caballus 98.24 0.00e+00 880.00
IUUC-Eeu-034517 Erinaceus europaeus 82.76 2.00e-137 481.00
IUUC-Fca-035678 Felis catus 98.68 0.00e+00 884.00
IUUC-Fal-036805 Ficedula albicollis 93.61 0.00e+00 848.00
IUUC-Gmo-039517 Gadus morhua 78.63 0.00e+00 726.00
IUUC-Gga-040872 Gallus gallus 92.73 0.00e+00 843.00
IUUC-Gac-042579 Gasterosteus aculeatus 77.09 0.00e+00 696.00
IUUC-Ggo-045157 Gorilla gorilla 98.46 0.00e+00 882.00
IUUC-Hsa-045668 Homo sapiens 98.68 0.00e+00 884.00
IUUC-Itr-048301 Ictidomys tridecemlineatus 98.68 0.00e+00 881.00
IUUC-Lch-049887 Latimeria chalumnae 87.00 0.00e+00 785.00
IUUC-Loc-052187 Lepisosteus oculatus 83.26 0.00e+00 755.00
IUUC-Laf-053958 Loxodonta africana 98.24 0.00e+00 880.00
IUUC-Mcc-054903 Macaca mulatta 98.46 0.00e+00 883.00
IUUC-Meu-056564 Macropus eugenii 94.05 0.00e+00 838.00
IUUC-Mga-060169 Meleagris gallopavo 92.95 0.00e+00 844.00
IUUC-Mdo-061997 Monodelphis domestica 95.81 0.00e+00 863.00
IUUC-Mmu-063709 Mus musculus 99.56 0.00e+00 886.00
IUUC-Mpu-066578 Mustela putorius furo 98.68 0.00e+00 884.00
IUUC-Mlu-067555 Myotis lucifugus 98.46 0.00e+00 880.00
IUUC-Nle-069408 Nomascus leucogenys 98.46 0.00e+00 882.00
IUUC-Opr-070771 Ochotona princeps 76.33 2.00e-158 551.00
IUUC-Ont-072597 Oreochromis niloticus 81.72 0.00e+00 721.00
IUUC-Oan-072768 Ornithorhynchus anatinus 98.68 4.00e-121 426.00
IUUC-Ocu-074312 Oryctolagus cuniculus 98.68 0.00e+00 884.00
IUUC-Ola-086660 Oryzias latipes 81.50 0.00e+00 715.00
IUUC-Oga-088471 Otolemur garnettii 87.61 0.00e+00 763.00
IUUC-Oar-089744 Ovis aries 97.14 0.00e+00 866.00
IUUC-Ptr-090977 Pan troglodytes 98.68 0.00e+00 884.00
IUUC-Pan-092850 Papio anubis 98.46 0.00e+00 883.00
IUUC-Psi-093875 Pelodiscus sinensis 92.73 0.00e+00 838.00
IUUC-Pma-094257 Petromyzon marinus 69.52 0.00e+00 629.00
IUUC-Pfo-096359 Poecilia formosa 81.72 0.00e+00 719.00
IUUC-Pab-097730 Pongo abelii 98.46 0.00e+00 882.00
IUUC-Pca-101089 Procavia capensis 97.87 2.00e-79 289.00
IUUC-Pva-102555 Pteropus vampyrus 98.90 0.00e+00 884.00
IUUC-Sha-107582 Sarcophilus harrisii 95.82 0.00e+00 861.00
IUUC-Sar-112994 Sorex araneus 76.82 2.00e-138 485.00
IUUC-Ssc-115254 Sus scrofa 98.68 0.00e+00 882.00
IUUC-Tgu-117122 Taeniopygia guttata 93.39 0.00e+00 848.00
IUUC-Tru-118198 Takifugu rubripes 81.94 0.00e+00 746.00
IUUC-Tsy-119295 Tarsius syrichta 98.02 0.00e+00 879.00
IUUC-Tni-120193 Tetraodon nigroviridis 80.62 0.00e+00 709.00
IUUC-Tbe-127929 Tupaia belangeri 98.02 0.00e+00 841.00
IUUC-Ttr-128816 Tursiops truncatus 98.68 0.00e+00 884.00
IUUC-Vpa-130198 Vicugna pacos 99.16 0.00e+00 688.00
IUUC-Xtr-132551 Xenopus tropicalis 88.11 0.00e+00 799.00
Created Date 25-Jun-2017

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