iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-003327

Ensembl Protein ID

ENSAPLP00000010766.1

UniProt Accession

U3IU43; U3IU43_ANAPL

Genbank Protein ID

ENSAPLP00000010766

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01054779

Gene Name

STRAP

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000011004.1	ENSAPLT00000011484.1	ENSAPLP00000010766.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.30e-25	88.1	228	262
UBD/Beta-Prp	8.80e-41	139.7	13	264

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sdtll.vsGsdDgtikvWDlrtg 33
           gH ++++c++f +d+ l +sGs Dgt+++W ++ g
   Q: 228  GHFGPIHCVRFsPDGELyASGSEDGTLRLWQTTVG 262
           799*********997776************98765 PP

UBD/Beta-Prp

   S: 41   tgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcl 129
           tg+ + ++ gh+++v+  ++++d+   +t++ D t+kvwd  +g+ ++tl  h++ v s++f +++++l++G++d+ +r++dl++ +  
   Q: 13   TGDWIGTFLGHKGAVWGATLNKDATKAATAAADFTAKVWDAVSGDELITLA-HKHIVKSVDFTQDSNYLLTGGQDKLLRIYDLSKPEAE 100
           567799*********************************************.************************************* PP
   S: 130  eetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsng.......................... 192
            ++ sgh++ +  + +++d++ + s ++D+tvrlWd +t++ ++ l      sv s+++ ++g                          
   Q: 101  PDVVSGHTSGIKKALWSSDDKQILS-ADDKTVRLWDRSTMTEVKALN--VAMSVSSMEYVPEGqilvitygktiafhsaetleqiksfe 186
           ******************9987766.69*********6666666663..4666666665555555555555555555555555555555 PP
   S: 193  ..............kelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdl 256
                         ++lv+g++d ++  +d+ tge +++++gh  ++ +vrfsp++e+++sgs+Dg++r+W ++ g++
   Q: 187  apatinsaslhpekECLVAGGEDFKLYKYDYNTGEELESYKGHFGPIHCVRFSPDGELYASGSEDGTLRLWQTTVGKT 264
           55555555555555*********************************************************8776665 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

CEDGKPMLRQ GDTGDWIGTF LGHKGAVWGA TLNKDATKAA TAAADFTAKV WDAVSGDELI 60
TLAHKHIVKS VDFTQDSNYL LTGGQDKLLR IYDLSKPEAE PDVVSGHTSG IKKALWSSDD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGTGAAGATG GTAAGCCTAT GCTACGTCAG GGCGACACAG GAGACTGGAT TGGCACATTT 60
CTAGGCCATA AAGGTGCTGT TTGGGGTGCT ACTTTGAACA AGGATGCCAC AAAAGCAGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0032797--C:SMN complex
GO:0034719--C:SMN-Sm protein complex
GO:0003723--F:RNA binding
GO:0030277--P:maintenance of gastrointestinal epithelium
GO:0010633--P:negative regulation of epithelial cell migration
GO:0050680--P:negative regulation of epithelial cell proliferation
GO:0010719--P:negative regulation of epithelial to mesenchymal transition
GO:0060394--P:negative regulation of pathway-restricted SMAD protein phosphorylation
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0030512--P:negative regulation of transforming growth factor beta receptor signaling pathway
GO:0000387--P:spliceosomal snRNP assembly

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000668	Aegilops tauschii	46.54	4.00e-62	231.00
IUUC-Aml-002091	Ailuropoda melanoleuca	86.62	9.00e-142	495.00
IUUC-Atr-002571	Amborella trichopoda	49.43	3.00e-64	238.00
IUUC-Aca-005324	Anolis carolinensis	90.51	4.00e-152	530.00
IUUC-Aly-006452	Arabidopsis lyrata	46.72	2.00e-62	231.00
IUUC-Ath-006646	Arabidopsis thaliana	46.72	2.00e-62	232.00
IUUC-Acl-008014	Aspergillus clavatus	39.54	3.00e-40	158.00
IUUC-Afl-008701	Aspergillus flavus	37.84	5.00e-25	108.00
IUUC-Afu-008942	Aspergillus fumigatus	28.65	2.00e-26	112.00
IUUC-Ani-009394	Aspergillus nidulans	39.40	9.00e-41	160.00
IUUC-Ang-009593	Aspergillus niger	35.85	2.00e-26	112.00
IUUC-Aor-010206	Aspergillus oryzae	40.98	2.00e-41	162.00
IUUC-Ame-011328	Astyanax mexicanus	79.35	2.00e-118	418.00
IUUC-Bgr-012308	Blumeria graminis	39.81	1.00e-47	183.00
IUUC-Bta-013429	Bos taurus	85.76	2.00e-142	498.00
IUUC-Bci-013803	Botrytis cinerea	40.71	4.00e-46	177.00
IUUC-Bdi-014996	Brachypodium distachyon	45.95	3.00e-62	231.00
IUUC-Bol-016595	Brassica oleracea	47.69	2.00e-64	238.00
IUUC-Bra-017775	Brassica rapa	46.56	7.00e-63	235.00
IUUC-Cja-018740	Callithrix jacchus	85.62	3.00e-140	490.00
IUUC-Cfa-021145	Canis familiaris	86.08	3.00e-143	500.00
IUUC-Cpo-022373	Cavia porcellus	85.44	2.00e-142	498.00
IUUC-Cre-022806	Chlamydomonas reinhardtii	43.63	7.00e-50	190.00
IUUC-Csa-023098	Chlorocebus sabaeus	84.81	8.00e-141	492.00
IUUC-Cho-024856	Choloepus hoffmanni	77.53	6.00e-119	419.00
IUUC-Cin-025541	Ciona intestinalis	56.46	3.00e-89	321.00
IUUC-Csv-026287	Ciona savignyi	55.64	5.00e-80	290.00
IUUC-Cgl-026513	Colletotrichum gloeosporioides	40.20	9.00e-45	173.00
IUUC-Cne-026869	Cryptococcus neoformans	45.39	6.00e-59	220.00
IUUC-Dre-028457	Danio rerio	79.20	4.00e-120	423.00
IUUC-Dno-029213	Dasypus novemcinctus	86.08	4.00e-143	500.00
IUUC-Dse-031350	Dothistroma septosporum	40.73	4.00e-45	174.00
IUUC-Dme-031857	Drosophila melanogaster	60.58	2.00e-90	325.00
IUUC-Ete-032558	Echinops telfairi	78.03	2.00e-88	318.00
IUUC-Eca-033934	Equus caballus	86.08	6.00e-143	499.00
IUUC-Eeu-034650	Erinaceus europaeus	83.90	6.00e-124	436.00
IUUC-Fca-035909	Felis catus	86.08	2.00e-141	494.00
IUUC-Fal-036706	Ficedula albicollis	97.14	1.00e-154	538.00
IUUC-Fox-037780	Fusarium oxysporum	41.75	2.00e-44	172.00
IUUC-Fso-038197	Fusarium solani	40.86	9.00e-47	180.00
IUUC-Gmo-039707	Gadus morhua	76.19	7.00e-111	392.00
IUUC-Ggr-040054	Gaeumannomyces graminis	39.13	4.00e-46	178.00
IUUC-Gga-040901	Gallus gallus	97.78	9.00e-160	555.00
IUUC-Gac-041876	Gasterosteus aculeatus	80.22	1.00e-118	419.00
IUUC-Gma-044014	Glycine max	49.04	2.00e-64	239.00
IUUC-Ggo-044583	Gorilla gorilla	78.55	6.00e-125	439.00
IUUC-Hsa-046553	Homo sapiens	85.03	2.00e-139	488.00
IUUC-Hvu-047544	Hordeum vulgare	46.92	1.00e-62	233.00
IUUC-Itr-047980	Ictidomys tridecemlineatus	86.39	2.00e-143	501.00
IUUC-Lch-050078	Latimeria chalumnae	78.23	2.00e-129	454.00
IUUC-Lpe-051246	Leersia perrieri	46.92	1.00e-63	236.00
IUUC-Loc-052598	Lepisosteus oculatus	82.12	2.00e-122	431.00
IUUC-Lma-053226	Leptosphaeria maculans	45.04	2.00e-48	185.00
IUUC-Laf-054053	Loxodonta africana	86.39	3.00e-143	500.00
IUUC-Mcc-054652	Macaca mulatta	85.35	9.00e-140	489.00
IUUC-Mor-057256	Magnaporthe oryzae	37.21	7.00e-44	170.00
IUUC-Mpo-057303	Magnaporthe poae	38.87	3.00e-46	178.00
IUUC-Mtr-058421	Medicago truncatula	48.66	2.00e-64	238.00
IUUC-Mla-059073	Melampsora laricipopulina	45.07	9.00e-54	203.00
IUUC-Mga-059664	Meleagris gallopavo	98.10	6.00e-159	553.00
IUUC-Mvi-060534	Microbotryum violaceum	37.66	3.00e-35	142.00
IUUC-Mmr-061044	Microcebus murinus	87.93	2.00e-138	484.00
IUUC-Mdo-063019	Monodelphis domestica	86.08	2.00e-142	498.00
IUUC-Mmu-064092	Mus musculus	86.71	1.00e-143	501.00
IUUC-Mac-065143	Musa acuminata	49.23	2.00e-63	235.00
IUUC-Mpu-066557	Mustela putorius furo	86.39	2.00e-143	501.00
IUUC-Mlu-068179	Myotis lucifugus	86.08	1.00e-142	498.00
IUUC-Nfi-068553	Neosartorya fischeri	39.54	1.00e-39	156.00
IUUC-Ncr-068934	Neurospora crassa	37.83	8.00e-40	157.00
IUUC-Nle-069482	Nomascus leucogenys	85.30	5.00e-139	486.00
IUUC-Opr-071055	Ochotona princeps	64.24	9.00e-93	333.00
IUUC-Ont-072663	Oreochromis niloticus	72.78	2.00e-113	401.00
IUUC-Ocu-074942	Oryctolagus cuniculus	86.08	6.00e-143	499.00
IUUC-Oba-075160	Oryza barthii	46.92	1.00e-63	236.00
IUUC-Obr-076864	Oryza brachyantha	46.92	2.00e-63	235.00
IUUC-Ogl-077076	Oryza glaberrima	46.92	1.00e-63	236.00
IUUC-Ogu-078591	Oryza glumaepatula	46.92	1.00e-63	236.00
IUUC-Oin-079631	Oryza indica	46.15	6.00e-63	233.00
IUUC-Olo-080389	Oryza longistaminata	42.92	2.00e-49	188.00
IUUC-Ome-081693	Oryza meridionalis	46.15	9.00e-63	233.00
IUUC-Oni-082190	Oryza nivara	47.31	7.00e-64	236.00
IUUC-Opu-084163	Oryza punctata	46.92	1.00e-63	236.00
IUUC-Oru-084730	Oryza rufipogon	46.92	1.00e-63	236.00
IUUC-Osa-086010	Oryza sativa	46.92	1.00e-63	236.00
IUUC-Ola-086704	Oryzias latipes	72.56	5.00e-121	427.00
IUUC-Olu-087796	Ostreococcus lucimarinus	50.77	1.00e-66	246.00
IUUC-Oga-088932	Otolemur garnettii	62.81	4.00e-86	311.00
IUUC-Oar-090398	Ovis aries	86.08	6.00e-143	499.00
IUUC-Ptr-091202	Pan troglodytes	84.81	1.00e-140	492.00
IUUC-Pan-091948	Papio anubis	85.13	4.00e-141	493.00
IUUC-Psi-093863	Pelodiscus sinensis	91.14	1.00e-152	531.00
IUUC-Pma-094255	Petromyzon marinus	77.74	8.00e-120	422.00
IUUC-Pno-095075	Phaeosphaeria nodorum	46.07	1.00e-49	189.00
IUUC-Ppa-095206	Physcomitrella patens	48.30	8.00e-68	249.00
IUUC-Pfo-096438	Poecilia formosa	73.50	7.00e-120	422.00
IUUC-Pab-097994	Pongo abelii	84.49	1.00e-140	492.00
IUUC-Pop-099172	Populus trichocarpa	48.08	9.00e-64	236.00
IUUC-Pca-100761	Procavia capensis	77.59	4.00e-117	413.00
IUUC-Ppe-102035	Prunus persica	49.43	3.00e-62	231.00
IUUC-Pva-102794	Pteropus vampyrus	77.53	4.00e-123	434.00
IUUC-Pgr-103581	Puccinia graminis	46.64	4.00e-54	204.00
IUUC-Ptt-103862	Puccinia triticina	46.43	3.00e-53	201.00
IUUC-Pte-104245	Pyrenophora teres	46.43	9.00e-51	193.00
IUUC-Pyt-104537	Pyrenophora triticirepentis	46.43	9.00e-51	193.00
IUUC-Rno-105712	Rattus norvegicus	86.39	5.00e-143	499.00
IUUC-Sha-107568	Sarcophilus harrisii	85.76	2.00e-142	498.00
IUUC-Ssl-108655	Sclerotinia sclerotiorum	39.74	4.00e-44	171.00
IUUC-Smo-108784	Selaginella moellendorffii	51.92	6.00e-70	257.00
IUUC-Sit-109807	Setaria italica	48.85	2.00e-64	239.00
IUUC-Sly-111555	Solanum lycopersicum	47.69	2.00e-62	232.00
IUUC-Stu-111953	Solanum tuberosum	46.92	1.00e-61	229.00
IUUC-Sar-113491	Sorex araneus	78.42	3.00e-106	377.00
IUUC-Sbi-114290	Sorghum bicolor	48.46	9.00e-65	239.00
IUUC-Sre-115008	Sporisorium reilianum	41.70	1.00e-51	196.00
IUUC-Ssc-116392	Sus scrofa	85.94	7.00e-141	493.00
IUUC-Tgu-116835	Taeniopygia guttata	97.15	1.00e-155	541.00
IUUC-Tru-117558	Takifugu rubripes	71.92	3.00e-120	424.00
IUUC-Tsy-119522	Tarsius syrichta	82.59	7.00e-131	459.00
IUUC-Tni-120330	Tetraodon nigroviridis	78.68	1.00e-112	398.00
IUUC-Tca-121759	Theobroma cacao	49.81	7.00e-64	237.00
IUUC-Tre-122163	Trichoderma reesei	41.47	1.00e-44	173.00
IUUC-Tvi-122609	Trichoderma virens	43.14	1.00e-46	179.00
IUUC-Tae-123053	Triticum aestivum	46.54	4.00e-62	231.00
IUUC-Tur-126808	Triticum urartu	46.51	9.00e-62	229.00
IUUC-Tme-127137	Tuber melanosporum	46.86	8.00e-59	220.00
IUUC-Tbe-127324	Tupaia belangeri	71.30	3.00e-76	278.00
IUUC-Ttr-128202	Tursiops truncatus	85.76	9.00e-142	495.00
IUUC-Uma-129433	Ustilago maydis	41.70	5.00e-50	190.00
IUUC-Vda-129675	Verticillium dahliae	37.17	9.00e-43	167.00
IUUC-Vpa-130382	Vicugna pacos	86.39	3.00e-143	500.00
IUUC-Vvi-130921	Vitis vinifera	49.43	8.00e-66	243.00
IUUC-Xtr-132648	Xenopus tropicalis	67.70	3.00e-107	381.00
IUUC-Xma-133969	Xiphophorus maculatus	68.45	1.00e-109	389.00
IUUC-Yli-134670	Yarrowia lipolytica	33.94	7.00e-36	144.00
IUUC-Zma-135878	Zea mays	48.46	6.00e-65	240.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence