iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tgu-117151

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABQF01037511

Gene Name

SOCS3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000003345.1	ENSTGUT00000003480.1	ENSTGUP00000003446.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	84.00	8.00e-96	347.00	IUUC-Hsa-046909

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Taeniopygia guttata

Protein Sequence
(Fasta)

MVTHSKFPAA GMSRPLDTSL RLKTFSSKSE YQLVVNTVRK LQESGFYWST VTGGEANLLL 60
STEPAGTFLI RDSSDQRHFF TLSVKTESGT KNLRIQCEGG SFSLQSDPHS SQPVPRFDCV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTCACCC ACAGCAAGTT CCCCGCCGCC GGGATGAGTC GCCCCCTCGA CACCAGCCTG 60
CGCCTCAAGA CGTTCAGCTC CAAGAGCGAG TACCAGCTGG TGGTGAACAC CGTACGCAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028414--SOCS3
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005622--C:intracellular
GO:0007259--P:JAK-STAT cascade
GO:0043066--P:negative regulation of apoptotic process
GO:0050728--P:negative regulation of inflammatory response
GO:0046627--P:negative regulation of insulin receptor signaling pathway
GO:0042512--P:negative regulation of tyrosine phosphorylation of Stat1 protein
GO:0042518--P:negative regulation of tyrosine phosphorylation of Stat3 protein
GO:0045597--P:positive regulation of cell differentiation
GO:0016567--P:protein ubiquitination

KEGG

tgu:100227853

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001529	Ailuropoda melanoleuca	80.44	3.00e-99	353.00
IUUC-Atr-003014	Amborella trichopoda	39.39	1.40e+00	26.20
IUUC-Apl-003607	Anas platyrhynchos	94.26	1.00e-103	367.00
IUUC-Aca-005063	Anolis carolinensis	87.68	2.00e-104	370.00
IUUC-Ath-006990	Arabidopsis thaliana	31.76	2.00e-02	34.30
IUUC-Acl-008048	Aspergillus clavatus	42.31	9.40e-01	27.70
IUUC-Ame-010859	Astyanax mexicanus	56.70	1.00e-67	248.00
IUUC-Bta-012817	Bos taurus	80.35	2.00e-102	364.00
IUUC-Cja-019605	Callithrix jacchus	80.89	1.00e-101	361.00
IUUC-Cfa-021231	Canis familiaris	81.33	8.00e-101	358.00
IUUC-Cpo-022003	Cavia porcellus	80.26	2.00e-100	357.00
IUUC-Csa-023511	Chlorocebus sabaeus	81.06	1.00e-101	361.00
IUUC-Dre-028536	Danio rerio	63.08	4.00e-74	270.00
IUUC-Dno-029003	Dasypus novemcinctus	80.89	7.00e-101	358.00
IUUC-Eca-034205	Equus caballus	69.83	1.00e-62	231.00
IUUC-Fca-036317	Felis catus	79.82	6.00e-98	349.00
IUUC-Gmo-038777	Gadus morhua	62.96	7.00e-36	142.00
IUUC-Gga-041258	Gallus gallus	97.61	2.00e-110	390.00
IUUC-Gac-041837	Gasterosteus aculeatus	60.56	5.00e-67	246.00
IUUC-Ggo-045620	Gorilla gorilla	81.06	1.00e-101	361.00
IUUC-Hsa-046909	Homo sapiens	81.06	1.00e-101	361.00
IUUC-Itr-048023	Ictidomys tridecemlineatus	79.06	1.00e-101	362.00
IUUC-Lch-049510	Latimeria chalumnae	71.36	3.00e-82	296.00
IUUC-Loc-052863	Lepisosteus oculatus	68.69	5.00e-81	293.00
IUUC-Laf-054136	Loxodonta africana	79.82	7.00e-101	358.00
IUUC-Mcc-055383	Macaca mulatta	81.06	1.00e-101	361.00
IUUC-Meu-056153	Macropus eugenii	81.42	4.00e-102	363.00
IUUC-Mmr-061185	Microcebus murinus	80.97	3.00e-100	357.00
IUUC-Mdo-061819	Monodelphis domestica	81.33	2.00e-103	367.00
IUUC-Mmu-064231	Mus musculus	84.44	2.00e-104	370.00
IUUC-Mpu-066691	Mustela putorius furo	81.78	8.00e-101	358.00
IUUC-Mlu-067673	Myotis lucifugus	81.14	2.00e-103	367.00
IUUC-Ont-072406	Oreochromis niloticus	61.03	8.00e-72	262.00
IUUC-Oan-073249	Ornithorhynchus anatinus	80.38	2.00e-91	327.00
IUUC-Ocu-074935	Oryctolagus cuniculus	80.00	5.00e-28	114.00
IUUC-Ola-087373	Oryzias latipes	50.53	3.00e-49	187.00
IUUC-Oga-088041	Otolemur garnettii	81.70	1.00e-101	361.00
IUUC-Oar-089646	Ovis aries	78.60	2.00e-97	347.00
IUUC-Ptr-091502	Pan troglodytes	81.06	1.00e-101	361.00
IUUC-Pan-091934	Papio anubis	81.06	1.00e-101	361.00
IUUC-Pfo-096412	Poecilia formosa	45.54	3.00e-49	187.00
IUUC-Pab-098554	Pongo abelii	81.06	1.00e-101	361.00
IUUC-Rno-105874	Rattus norvegicus	83.26	9.00e-104	368.00
IUUC-Sha-107151	Sarcophilus harrisii	80.26	9.00e-102	362.00
IUUC-Ssc-115722	Sus scrofa	73.10	4.00e-61	226.00
IUUC-Tru-118428	Takifugu rubripes	60.09	2.00e-69	254.00
IUUC-Tni-120590	Tetraodon nigroviridis	60.56	4.00e-69	253.00
IUUC-Ttr-129065	Tursiops truncatus	79.65	3.00e-101	360.00
IUUC-Xtr-132167	Xenopus tropicalis	72.25	7.00e-84	302.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence