iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-049412

Ensembl Protein ID

ENSLACP00000007941.1

UniProt Accession

H3AE70; H3AE70_LATCH

Genbank Protein ID

ENSLACP00000007941

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AFYH01182807

Gene Name

HIC1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000007028.1	ENSLACT00000008007.1	ENSLACP00000007941.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	1.60e-12	47.8	51	111

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveik.d.vqpevfrallkFlYtgkld 66
           +Dvi+vv++  f+ahk +LaasS ++++l  +        + ++++ + v+p+ fr +l+++Ytg+l+
   Q: 51   CDVIIVVQNALFRAHKNILAASSVYLKSLVVH-------DNLINLDhEmVSPSIFRIILDYIYTGRLS 111
           9*****************************66.......5789999549*****************97 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

MIIQKDLGWM AEGTGHPGGR LNTMLDAMEV PSHARQLLLQ LNTQRTKGFL CDVIIVVQNA 60
LFRAHKNILA ASSVYLKSLV VHDNLINLDH EMVSPSIFRI ILDYIYTGRL SDLDQASEQN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAACACTACA GTCACATAGA GAGCCCTTTA TCTAACCGAC AGTATTACTT TAAACATAAA 60
AATAGCAGAG GAAATTGCTA AAATAAAATC AGAGAAAACT GATGCTGGAG CAGGCACGTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000210--BTB/POZ_dom
IPR028424--HIC1
IPR011333--SKP1/BTB/POZ
IPR013087--Znf_C2H2_type

PROSITE

PS50097--BTB
PS00028--ZINC_FINGER_C2H2_1
PS50157--ZINC_FINGER_C2H2_2

Pfam

PF00651--BTB

SMART

SM00225--BTB
SM00355--ZnF_C2H2

Gene Ontology

GO:0005622--C:intracellular
GO:0003677--F:DNA binding
GO:0046872--F:metal ion binding
GO:0003700--F:transcription factor activity, sequence-specific DNA binding
GO:0008630--P:intrinsic apoptotic signaling pathway in response to DNA damage
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter

KEGG

lcm:102359906

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001347	Ailuropoda melanoleuca	57.65	6.00e-106	378.00
IUUC-Aca-004680	Anolis carolinensis	81.21	3.00e-73	269.00
IUUC-Ame-010967	Astyanax mexicanus	53.64	0.00e+00	660.00
IUUC-Cja-019621	Callithrix jacchus	83.33	2.00e-39	154.00
IUUC-Cfa-020731	Canis familiaris	57.60	8.00e-110	391.00
IUUC-Cpo-021326	Cavia porcellus	52.93	4.00e-176	611.00
IUUC-Csa-023645	Chlorocebus sabaeus	55.64	5.00e-108	385.00
IUUC-Dre-028027	Danio rerio	50.40	1.00e-172	600.00
IUUC-Dno-029125	Dasypus novemcinctus	74.32	3.00e-80	293.00
IUUC-Eca-033737	Equus caballus	71.96	1.00e-79	290.00
IUUC-Fal-036980	Ficedula albicollis	66.77	0.00e+00	798.00
IUUC-Gmo-039209	Gadus morhua	46.59	2.00e-129	456.00
IUUC-Gga-040708	Gallus gallus	69.85	0.00e+00	881.00
IUUC-Gac-041742	Gasterosteus aculeatus	57.03	3.00e-164	571.00
IUUC-Ggo-045081	Gorilla gorilla	71.96	8.00e-80	291.00
IUUC-Hsa-046769	Homo sapiens	55.40	6.00e-107	381.00
IUUC-Itr-048738	Ictidomys tridecemlineatus	71.96	1.00e-79	290.00
IUUC-Laf-053358	Loxodonta africana	55.88	4.00e-107	382.00
IUUC-Mcc-054981	Macaca mulatta	55.64	7.00e-108	384.00
IUUC-Meu-056181	Macropus eugenii	49.16	2.00e-81	296.00
IUUC-Mga-059592	Meleagris gallopavo	80.00	3.00e-132	464.00
IUUC-Mmr-061560	Microcebus murinus	50.82	2.00e-170	592.00
IUUC-Mdo-062511	Monodelphis domestica	52.97	3.00e-156	545.00
IUUC-Mmu-064258	Mus musculus	56.97	6.00e-109	388.00
IUUC-Mpu-065911	Mustela putorius furo	57.60	1.00e-109	390.00
IUUC-Mlu-067531	Myotis lucifugus	71.96	1.00e-79	290.00
IUUC-Nle-069726	Nomascus leucogenys	73.62	6.00e-70	258.00
IUUC-Ont-072493	Oreochromis niloticus	53.63	0.00e+00	637.00
IUUC-Ocu-073887	Oryctolagus cuniculus	73.22	5.00e-79	288.00
IUUC-Ola-086584	Oryzias latipes	67.86	2.00e-109	389.00
IUUC-Oga-088774	Otolemur garnettii	53.44	3.00e-179	622.00
IUUC-Ptr-090786	Pan troglodytes	71.96	1.00e-79	290.00
IUUC-Pan-092901	Papio anubis	71.96	1.00e-79	290.00
IUUC-Pma-094179	Petromyzon marinus	71.79	2.00e-32	129.00
IUUC-Pfo-096282	Poecilia formosa	52.65	0.00e+00	654.00
IUUC-Pab-098162	Pongo abelii	71.96	1.00e-79	290.00
IUUC-Pva-102421	Pteropus vampyrus	56.86	3.00e-110	392.00
IUUC-Rno-105528	Rattus norvegicus	56.62	7.00e-106	378.00
IUUC-Sar-113478	Sorex araneus	67.80	1.00e-86	314.00
IUUC-Ssc-115420	Sus scrofa	55.75	1.00e-109	390.00
IUUC-Tgu-116642	Taeniopygia guttata	71.36	0.00e+00	871.00
IUUC-Tru-118583	Takifugu rubripes	53.54	2.00e-177	615.00
IUUC-Xtr-132210	Xenopus tropicalis	74.18	0.00e+00	983.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence