iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-037216

Ensembl Protein ID

ENSFALP00000010009.1

UniProt Accession

U3K4Q5; U3K4Q5_FICAL

Genbank Protein ID

ENSFALP00000010009

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01011325

Gene Name

USP18

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000009602.1	ENSFALT00000010049.1	ENSFALP00000010009.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.20e-59	201.0	59	374

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           +Gl Nlg tC +NS+LQ+ ++   +++ l +     +   +p  +  ++  ++  l+e+++ +k kav p++l  +l++  ++   + q
   Q: 59   VGLYNLGQTCCLNSLLQVFFMNIRFTRILRR-----ITVPSPARRRSSVPYQMLLLLEKMQCGKCKAVCPTDLAYCLAEHRVK--LFVQ 140
           6****************************99.....44445567889******************************977765..89** PP
   S: 90   qDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpg 178
            Da  ++  l + l++++                          k+ +  + +sdl+ +++++++ c++c  + ++++++l+l+lpv +
   Q: 141  YDAAQLFLTLWNLLKKQM--------------------------KNPELVEELSDLYTIRIQEHLACQKCSFEIKSNSTMLTLPLPVLD 203
           ******************..........................4566677799*********************************** PP
   S: 179  keetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfcts 267
            ++  +++l++cL+ f+ +e+l+g+n+++c++c +k+   ++++l +lP++L+lhLkRf+f+++ ++ +k++ ++ fp+eLd ++++t+
   Q: 204  ANSHRLKTLEHCLQYFFLPEKLTGQNMCFCQQCGRKTPFLQSMELVHLPQTLTLHLKRFCFERS-SRTHKLSHSLPFPQELDFREVLTE 291
           *************************************************************887.8999***************98888 PP
   S: 268  ....peekqke....kkkYeLiavvvHsGslssGHYvayvkn.ekgkWllfdDskVtevkeeevleetg.......staYvlfYkrr 338
                +    +    + +YeL+avv HsG +s+GHY+ay+++ ++ kW++f+Ds+V +v++++v+ + g       +taY+lfY+++
   Q: 292  nqcqAD----DrekaTWQYELFAVVAHSGYSSCGHYCAYIRSlTECKWYCFNDSQVCQVSWDDVKCTYGrsnlnwrETAYLLFYMKK 374
           333322....2455599*************************56666*******************888***************985 PP

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

MGQRSGRQER SKKPEVALSE TMEAEIEVQN NKEEIEEVKA KNQKLASVFG VADLKNEAVG 60
LYNLGQTCCL NSLLQVFFMN IRFTRILRRI TVPSPARRRS SVPYQMLLLL EKMQCGKCKA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCCCCCCCC CCCCCCCCCC CCCCCCCCCC CCCCCCCCCC CCCCCCCCCC CCCCCCCCCC 60
CCCCCCCCCC CCCCGTGCCA GCCCCGCCGT GCCAGCCCCG CCGTGCCATC CCCTCCGTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0019785--F:ISG15-specific protease activity
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0035634--P:response to stilbenoid
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

fab:101818763

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001615	Ailuropoda melanoleuca	54.66	8.00e-97	346.00
IUUC-Apl-004006	Anas platyrhynchos	76.25	4.00e-144	503.00
IUUC-Aca-005088	Anolis carolinensis	54.62	4.00e-106	377.00
IUUC-Ame-010606	Astyanax mexicanus	35.08	4.00e-46	177.00
IUUC-Bta-013036	Bos taurus	54.75	2.00e-98	351.00
IUUC-Cja-019052	Callithrix jacchus	53.61	2.00e-90	325.00
IUUC-Cfa-020554	Canis familiaris	54.30	5.00e-104	370.00
IUUC-Cpo-022421	Cavia porcellus	52.50	7.00e-105	373.00
IUUC-Csa-023737	Chlorocebus sabaeus	52.74	2.00e-60	224.00
IUUC-Cho-024807	Choloepus hoffmanni	47.67	1.00e-41	163.00
IUUC-Dre-027408	Danio rerio	35.85	6.00e-46	177.00
IUUC-Dno-029813	Dasypus novemcinctus	44.65	5.00e-75	273.00
IUUC-Dor-030532	Dipodomys ordii	52.44	2.00e-98	352.00
IUUC-Ete-032254	Echinops telfairi	50.00	4.00e-98	351.00
IUUC-Eca-033482	Equus caballus	56.01	2.00e-101	362.00
IUUC-Eeu-034451	Erinaceus europaeus	49.52	7.00e-57	213.00
IUUC-Fca-036313	Felis catus	57.41	2.00e-104	372.00
IUUC-Gmo-038649	Gadus morhua	33.54	6.00e-48	184.00
IUUC-Gga-041082	Gallus gallus	71.16	3.00e-144	504.00
IUUC-Gac-042439	Gasterosteus aculeatus	36.39	3.00e-50	191.00
IUUC-Ggo-044957	Gorilla gorilla	54.04	5.00e-82	296.00
IUUC-Hsa-046381	Homo sapiens	52.94	4.00e-106	377.00
IUUC-Itr-047918	Ictidomys tridecemlineatus	51.39	7.00e-102	363.00
IUUC-Loc-052688	Lepisosteus oculatus	36.99	3.00e-49	188.00
IUUC-Laf-054109	Loxodonta africana	52.13	4.00e-105	374.00
IUUC-Mcc-054814	Macaca mulatta	51.34	1.00e-106	379.00
IUUC-Meu-056253	Macropus eugenii	54.70	1.00e-79	289.00
IUUC-Mmr-061613	Microcebus murinus	54.90	2.00e-104	371.00
IUUC-Mdo-061890	Monodelphis domestica	50.87	4.00e-94	337.00
IUUC-Mmu-064329	Mus musculus	51.55	8.00e-95	340.00
IUUC-Mpu-066342	Mustela putorius furo	56.21	4.00e-104	370.00
IUUC-Mlu-067010	Myotis lucifugus	50.28	2.00e-99	355.00
IUUC-Nle-069148	Nomascus leucogenys	52.66	5.00e-105	374.00
IUUC-Opr-070988	Ochotona princeps	51.59	4.00e-46	178.00
IUUC-Ont-072039	Oreochromis niloticus	36.06	4.00e-50	191.00
IUUC-Oan-073740	Ornithorhynchus anatinus	47.84	1.00e-56	212.00
IUUC-Ocu-074498	Oryctolagus cuniculus	54.46	1.00e-92	332.00
IUUC-Ola-086753	Oryzias latipes	35.37	2.00e-48	186.00
IUUC-Oga-088497	Otolemur garnettii	52.74	3.00e-103	367.00
IUUC-Oar-089505	Ovis aries	56.60	5.00e-100	357.00
IUUC-Ptr-091656	Pan troglodytes	53.22	9.00e-108	383.00
IUUC-Pan-092498	Papio anubis	51.34	1.00e-106	379.00
IUUC-Psi-093409	Pelodiscus sinensis	61.75	3.00e-130	457.00
IUUC-Pfo-096507	Poecilia formosa	34.59	3.00e-47	181.00
IUUC-Pab-097828	Pongo abelii	56.43	7.00e-102	363.00
IUUC-Pca-100299	Procavia capensis	49.38	1.00e-57	216.00
IUUC-Pva-102972	Pteropus vampyrus	51.06	3.00e-94	338.00
IUUC-Rno-105738	Rattus norvegicus	48.13	2.00e-94	338.00
IUUC-Sha-107309	Sarcophilus harrisii	49.38	4.00e-85	307.00
IUUC-Sar-112983	Sorex araneus	52.98	7.00e-79	286.00
IUUC-Ssc-116049	Sus scrofa	54.89	3.00e-98	351.00
IUUC-Tgu-117115	Taeniopygia guttata	88.24	5.00e-171	592.00
IUUC-Tru-118022	Takifugu rubripes	35.06	2.00e-46	179.00
IUUC-Tsy-118986	Tarsius syrichta	56.45	3.00e-33	135.00
IUUC-Tni-120306	Tetraodon nigroviridis	36.81	1.00e-47	183.00
IUUC-Tbe-127768	Tupaia belangeri	44.83	5.00e-56	211.00
IUUC-Ttr-128686	Tursiops truncatus	54.80	5.00e-98	350.00
IUUC-Xtr-132032	Xenopus tropicalis	43.26	2.00e-70	258.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence