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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Mmu-063663
Ensembl Protein ID ENSMUSP00000004646.6
UniProt Accession Q9WUM4; Q8VCQ5; COR1C_MOUSE
Genbank Protein ID AAD32705.1; BAC37609.1; BAC38722.1; BAC40144.1; AAH19444.1; AAH85498.1
Protein Name Coronin-1C; Coronin-3
Genbank Nucleotide ID AF143957; AK079327; AK082986; AK088101; BC019444; BC085498
Gene Name Coro1c
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000004530.12 ENSMUST00000164980.7 ENSMUSP00000129314.1
ENSMUSG00000004530.12 ENSMUST00000004646.12 ENSMUSP00000004646.6
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitemicroRNATRANSFACRepTar
miRNAMapRAID2
Protein-protein Interaction
IIDiRefIndexMentha
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusdbPTM
PHOSIDAmUbiSiDa
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 1.50e-15 57.7 78 110
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWDl 30
           gHt++v ++++   +d  ++sGs D+t++vW +
   Q: 78   GHTGPVLDIDWcphNDQVIASGSEDCTVMVWQI 110
           8***********977799*************86 PP
   
Organism Mus musculus
Functional Description
(View)

Functional Description


     May be involved in cytokinesis, motility, and signal transduction.
 May be involved in cytokinesis, motility, and signal transduction.
Protein Sequence
(Fasta)
MRRVVRQSKF RHVFGQAVKN DQCYDDIRVS RVTWDSSFCA VNPRFVAIII EASGGGAFLV 60
LPLHKTGRID KSYPTVCGHT GPVLDIDWCP HNDQVIASGS EDCTVMVWQI PENGLTLSLT 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063663|E3,WD_repeat|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GGGGCCCGCG CGCGCGAAGG CCTGGGCAGC GGCGGCCGCG CCCCTCCCCC GCGCGGCGCT 60
CAGTGCCAGG CGGGAGGCGG CAGCGGTTGG AGGCTTCGCG GGGCTTTGCA GCAGGGACTT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063663|E3,WD_repeat|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0007--Acetylation
KW-0009--Actin-binding
KW-1003--Cell membrane
KW-0966--Cell projection
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0472--Membrane
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat
Interpro

IPR027333--CORO1C
IPR015505--Coronin
IPR015048--DUF1899
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF08953--DUF1899
PF00400--WD40
SMART

SM01166--DUF1899
SM00320--WD40
Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0005737--C:cytoplasm
GO:0005856--C:cytoskeleton
GO:0016600--C:flotillin complex
GO:0005925--C:focal adhesion
GO:0030027--C:lamellipodium
GO:0016328--C:lateral plasma membrane
GO:0031982--C:vesicle
GO:0051015--F:actin filament binding
GO:0048365--F:Rac GTPase binding
GO:0000147--P:actin cortical patch assembly
GO:0030036--P:actin cytoskeleton organization
GO:0090630--P:activation of GTPase activity
GO:0045184--P:establishment of protein localization
GO:0010633--P:negative regulation of epithelial cell migration
GO:0051895--P:negative regulation of focal adhesion assembly
GO:0044387--P:negative regulation of protein kinase activity by regulation of protein phosphorylation
GO:0001933--P:negative regulation of protein phosphorylation
GO:1900025--P:negative regulation of substrate adhesion-dependent cell spreading
GO:0001755--P:neural crest cell migration
GO:0006909--P:phagocytosis
GO:2000394--P:positive regulation of lamellipodium morphogenesis
GO:0010632--P:regulation of epithelial cell migration
GO:0010762--P:regulation of fibroblast migration
GO:0051893--P:regulation of focal adhesion assembly
GO:0001932--P:regulation of protein phosphorylation
GO:1900027--P:regulation of ruffle assembly
GO:1900024--P:regulation of substrate adhesion-dependent cell spreading
KEGG mmu:23790
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002236 Ailuropoda melanoleuca 96.84 0.00e+00 960.00
IUUC-Apl-003861 Anas platyrhynchos 93.66 0.00e+00 939.00
IUUC-Acl-008280 Aspergillus clavatus 44.06 1.00e-98 354.00
IUUC-Afl-008393 Aspergillus flavus 44.31 3.00e-98 352.00
IUUC-Afu-008865 Aspergillus fumigatus 42.31 2.00e-94 340.00
IUUC-Ani-009155 Aspergillus nidulans 44.55 2.00e-99 356.00
IUUC-Ang-009523 Aspergillus niger 41.86 5.00e-89 322.00
IUUC-Aor-010049 Aspergillus oryzae 43.83 5.00e-95 342.00
IUUC-Ate-010368 Aspergillus terreus 43.61 9.00e-95 341.00
IUUC-Ame-011256 Astyanax mexicanus 82.70 0.00e+00 787.00
IUUC-Bta-013225 Bos taurus 96.20 0.00e+00 951.00
IUUC-Bci-013935 Botrytis cinerea 43.53 2.00e-100 360.00
IUUC-Cja-019948 Callithrix jacchus 97.05 0.00e+00 961.00
IUUC-Cfa-020591 Canis familiaris 97.26 0.00e+00 962.00
IUUC-Cpo-021480 Cavia porcellus 97.89 0.00e+00 969.00
IUUC-Csa-024152 Chlorocebus sabaeus 97.47 0.00e+00 967.00
IUUC-Cho-024687 Choloepus hoffmanni 97.24 0.00e+00 890.00
IUUC-Cgl-026456 Colletotrichum gloeosporioides 42.93 5.00e-96 345.00
IUUC-Dre-028541 Danio rerio 83.97 0.00e+00 797.00
IUUC-Dno-029552 Dasypus novemcinctus 97.70 0.00e+00 892.00
IUUC-Dse-031378 Dothistroma septosporum 42.71 5.00e-92 332.00
IUUC-Dme-032091 Drosophila melanogaster 53.67 2.00e-153 535.00
IUUC-Ete-032839 Echinops telfairi 88.19 0.00e+00 862.00
IUUC-Eca-034118 Equus caballus 96.20 0.00e+00 958.00
IUUC-Fca-035549 Felis catus 97.05 0.00e+00 961.00
IUUC-Fal-037065 Ficedula albicollis 93.23 0.00e+00 940.00
IUUC-Fox-037737 Fusarium oxysporum 43.03 4.00e-93 335.00
IUUC-Fso-038184 Fusarium solani 43.17 2.00e-98 353.00
IUUC-Gmo-038678 Gadus morhua 77.17 0.00e+00 777.00
IUUC-Ggr-039956 Gaeumannomyces graminis 42.89 3.00e-97 349.00
IUUC-Gga-040842 Gallus gallus 93.66 0.00e+00 944.00
IUUC-Gac-041543 Gasterosteus aculeatus 78.62 0.00e+00 776.00
IUUC-Ggo-044477 Gorilla gorilla 97.26 0.00e+00 964.00
IUUC-Hsa-046610 Homo sapiens 97.47 0.00e+00 964.00
IUUC-Itr-048583 Ictidomys tridecemlineatus 96.84 0.00e+00 959.00
IUUC-Lch-050453 Latimeria chalumnae 84.63 0.00e+00 832.00
IUUC-Loc-052911 Lepisosteus oculatus 84.78 0.00e+00 840.00
IUUC-Lma-053160 Leptosphaeria maculans 43.52 6.00e-100 358.00
IUUC-Laf-053416 Loxodonta africana 96.62 0.00e+00 959.00
IUUC-Mcc-055113 Macaca mulatta 97.47 0.00e+00 965.00
IUUC-Meu-056732 Macropus eugenii 81.47 0.00e+00 751.00
IUUC-Mor-056978 Magnaporthe oryzae 39.50 7.00e-100 358.00
IUUC-Mpo-057410 Magnaporthe poae 43.14 2.00e-90 327.00
IUUC-Mla-058883 Melampsora laricipopulina 42.08 9.00e-87 314.00
IUUC-Mga-060143 Meleagris gallopavo 93.66 0.00e+00 941.00
IUUC-Mmr-061130 Microcebus murinus 97.05 0.00e+00 961.00
IUUC-Mdo-062851 Monodelphis domestica 85.86 0.00e+00 800.00
IUUC-Mpu-066179 Mustela putorius furo 96.62 0.00e+00 959.00
IUUC-Mlu-068175 Myotis lucifugus 96.84 0.00e+00 960.00
IUUC-Nfi-068476 Neosartorya fischeri 43.07 5.00e-97 348.00
IUUC-Opr-070617 Ochotona princeps 96.20 0.00e+00 922.00
IUUC-Ont-072629 Oreochromis niloticus 82.45 0.00e+00 837.00
IUUC-Oan-073547 Ornithorhynchus anatinus 95.76 0.00e+00 949.00
IUUC-Ocu-074569 Oryctolagus cuniculus 95.78 0.00e+00 954.00
IUUC-Ola-086558 Oryzias latipes 80.71 0.00e+00 830.00
IUUC-Oga-089145 Otolemur garnettii 97.05 0.00e+00 963.00
IUUC-Oar-089654 Ovis aries 95.78 0.00e+00 950.00
IUUC-Ptr-090763 Pan troglodytes 97.47 0.00e+00 965.00
IUUC-Pan-091885 Papio anubis 97.16 0.00e+00 925.00
IUUC-Psi-093011 Pelodiscus sinensis 93.02 0.00e+00 932.00
IUUC-Pno-094994 Phaeosphaeria nodorum 44.39 1.00e-98 353.00
IUUC-Pfo-097309 Poecilia formosa 82.91 0.00e+00 846.00
IUUC-Pab-097542 Pongo abelii 88.82 0.00e+00 860.00
IUUC-Pca-100630 Procavia capensis 80.97 0.00e+00 770.00
IUUC-Pte-104194 Pyrenophora teres 42.89 5.00e-99 355.00
IUUC-Pyt-104437 Pyrenophora triticirepentis 42.89 5.00e-99 355.00
IUUC-Rno-105330 Rattus norvegicus 98.73 0.00e+00 978.00
IUUC-Sha-106695 Sarcophilus harrisii 93.41 0.00e+00 766.00
IUUC-Ssc-115348 Sus scrofa 95.99 0.00e+00 952.00
IUUC-Tgu-116597 Taeniopygia guttata 94.08 0.00e+00 941.00
IUUC-Tru-118425 Takifugu rubripes 81.18 0.00e+00 825.00
IUUC-Tsy-119223 Tarsius syrichta 87.13 0.00e+00 755.00
IUUC-Tni-120610 Tetraodon nigroviridis 80.76 0.00e+00 822.00
IUUC-Tbe-127679 Tupaia belangeri 87.85 0.00e+00 642.00
IUUC-Ttr-129226 Tursiops truncatus 86.88 0.00e+00 825.00
IUUC-Vpa-130339 Vicugna pacos 99.10 0.00e+00 702.00
IUUC-Xtr-132873 Xenopus tropicalis 75.16 0.00e+00 749.00
IUUC-Xma-134047 Xiphophorus maculatus 82.91 0.00e+00 847.00
Created Date 25-Jun-2017

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