iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ptr-091622

Ensembl Protein ID

ENSPTRP00000002112.5

UniProt Accession

H2PZV9; H2PZV9_PANTR

Genbank Protein ID

ENSPTRP00000002112

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AACZ03007747

Gene Name

OTUD7B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000001245.5	ENSPTRT00000002309.5	ENSPTRP00000002112.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/OTU	1.40e-37	129.2	184	365

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/OTU

   S: 2    lilktkgDGnCLlrAvsqsllgvfddds.lsdalveaLreltseylqkesdffsefieek...........edekefcqklvepe.... 74
           l+l+t+gDGnCLl+A+s +++g++d+d+ l++al+  + + +++++ k+++++++++++k           ++e++++ kl+++e    
   Q: 184  LPLATTGDGNCLLHAASLGMWGFHDRDLmLRKALYALMEKGVEKEALKRRWRWQQTQQNKesglvytedewQKEWNELIKLASSEprmh 272
           6899********************************************************************************98887 PP
   S: 75   ...akg.................eeihifaLaqiLsrpiivvdvdsles.........kvggillpllfpeek.lkkpivLlYrsgHYd 133
                g                 ee+h+f+La++L+rpi+vv++++l++         ++ggi+lpl++p+++ +++p+vL+Y+++H++
   Q: 273  lgtN-GancggvesseepvyeslEEFHVFVLAHVLRRPIVVVADTMLRDsggeafapiPFGGIYLPLEVPASQcHRSPLVLAYDQAHFS 360
           7650.255579****************************************************************************** PP
   S: 134  aLval 138
           aLv++
   Q: 361  ALVSM 365
           **986 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MTLDMDAVLS DFVRSTGAEP GLARDLLEGK NWDVNAALSD FEQLRQVHAG NLPPSFSEGS 60
GGSRTPEKGF SDREPTRPPR PILQRQDDIV QEKRLSRGIS HASSSIVSLA RSHVSSNGGG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCAAAAAGC CACTGCGGGA GGCCAGTCCC GATCAGTCCT TTCTGGCTCC AGCTCCAGAT 60
CCCGTGCGGA GCAACAGCTG CGGTCGCAGT CTCCACCTCC ATCGCCGTCG GGGGAGGGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003323--OTU_dom

PROSITE

PS50802--OTU

Pfam

PF02338--OTU

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0070530--F:K63-linked polyubiquitin binding
GO:1990380--F:Lys48-specific deubiquitinase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0006955--P:immune response
GO:0002385--P:mucosal immune response
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0032717--P:negative regulation of interleukin-8 production
GO:1900181--P:negative regulation of protein localization to nucleus
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0071947--P:protein deubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0035871--P:protein K11-linked deubiquitination
GO:0071108--P:protein K48-linked deubiquitination
GO:0070536--P:protein K63-linked deubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002119	Ailuropoda melanoleuca	94.96	0.00e+00	1109.00
IUUC-Apl-003567	Anas platyrhynchos	75.16	0.00e+00	893.00
IUUC-Bta-013398	Bos taurus	94.80	0.00e+00	1071.00
IUUC-Cel-018468	Caenorhabditis elegans	50.67	2.00e-86	313.00
IUUC-Cja-019965	Callithrix jacchus	98.74	0.00e+00	1185.00
IUUC-Cfa-020191	Canis familiaris	94.96	0.00e+00	1087.00
IUUC-Cpo-022232	Cavia porcellus	91.15	0.00e+00	993.00
IUUC-Csa-023593	Chlorocebus sabaeus	98.74	0.00e+00	1181.00
IUUC-Csv-026177	Ciona savignyi	28.87	2.00e-03	35.80
IUUC-Dno-029900	Dasypus novemcinctus	94.49	0.00e+00	1070.00
IUUC-Dor-031121	Dipodomys ordii	85.38	0.00e+00	697.00
IUUC-Ete-032473	Echinops telfairi	89.13	0.00e+00	1023.00
IUUC-Eca-033946	Equus caballus	95.01	0.00e+00	1055.00
IUUC-Eeu-034670	Erinaceus europaeus	93.54	0.00e+00	1043.00
IUUC-Fca-035871	Felis catus	95.43	0.00e+00	1070.00
IUUC-Fso-038203	Fusarium solani	29.00	3.90e-02	33.90
IUUC-Gmo-039373	Gadus morhua	77.25	0.00e+00	688.00
IUUC-Gga-041105	Gallus gallus	76.24	0.00e+00	887.00
IUUC-Gac-041806	Gasterosteus aculeatus	77.78	0.00e+00	732.00
IUUC-Ggo-045472	Gorilla gorilla	99.53	0.00e+00	1142.00
IUUC-Hsa-046473	Homo sapiens	99.84	0.00e+00	1151.00
IUUC-Itr-048841	Ictidomys tridecemlineatus	95.43	0.00e+00	1077.00
IUUC-Lch-050432	Latimeria chalumnae	75.38	0.00e+00	883.00
IUUC-Mcc-055261	Macaca mulatta	98.43	0.00e+00	1181.00
IUUC-Meu-056477	Macropus eugenii	81.92	0.00e+00	835.00
IUUC-Mga-059533	Meleagris gallopavo	77.73	0.00e+00	885.00
IUUC-Mdo-062847	Monodelphis domestica	88.36	0.00e+00	968.00
IUUC-Mmu-064260	Mus musculus	89.94	0.00e+00	1003.00
IUUC-Mpu-066876	Mustela putorius furo	88.23	0.00e+00	996.00
IUUC-Mlu-068039	Myotis lucifugus	95.44	0.00e+00	1076.00
IUUC-Nle-069260	Nomascus leucogenys	98.90	0.00e+00	1138.00
IUUC-Opr-070564	Ochotona princeps	91.61	0.00e+00	792.00
IUUC-Ocu-073824	Oryctolagus cuniculus	95.19	0.00e+00	957.00
IUUC-Opu-083273	Oryza punctata	24.36	4.80e-02	32.70
IUUC-Oga-088124	Otolemur garnettii	94.81	0.00e+00	1070.00
IUUC-Oar-090086	Ovis aries	95.59	0.00e+00	1079.00
IUUC-Pan-092724	Papio anubis	98.11	0.00e+00	1173.00
IUUC-Psi-093333	Pelodiscus sinensis	73.29	0.00e+00	847.00
IUUC-Pfo-096563	Poecilia formosa	77.85	0.00e+00	724.00
IUUC-Pab-098667	Pongo abelii	99.06	0.00e+00	1138.00
IUUC-Pva-102136	Pteropus vampyrus	94.49	0.00e+00	1080.00
IUUC-Rno-105546	Rattus norvegicus	90.57	0.00e+00	1016.00
IUUC-Sha-106732	Sarcophilus harrisii	86.18	0.00e+00	839.00
IUUC-Sar-113562	Sorex araneus	82.86	0.00e+00	858.00
IUUC-Ssc-116191	Sus scrofa	95.12	0.00e+00	1066.00
IUUC-Tgu-116942	Taeniopygia guttata	76.96	0.00e+00	760.00
IUUC-Tsy-119343	Tarsius syrichta	90.08	0.00e+00	1023.00
IUUC-Tur-126860	Triticum urartu	24.39	3.60e-02	32.70
IUUC-Tbe-127283	Tupaia belangeri	94.55	0.00e+00	762.00
IUUC-Ttr-128692	Tursiops truncatus	90.24	0.00e+00	957.00
IUUC-Xtr-132888	Xenopus tropicalis	79.04	0.00e+00	758.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence